<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP06508

Description "Coactivator CBP, KIX domain-containing protein"
SequenceMVVDIYVAGDLPTAMDTSNWRPNQGGTGGGDSSMESVDWRTQLPADTRHKIVNKILDNLKKHLAFSGQEKLHEIKNIALRFEEKIYHGATSHSDYMRKISIKLLAMENRAANPIANSLQSNSAGNSANPSDPEKENIPLISGSLEGANQTAKEMRLPEVTSIRKFYEIFVISPLSNMDIIVSHSSQGMQQVNNQGQSLNHPQAGQQILPPSIHNNIASSGGQGSAGISSALQPGSSLSQSTMPIISGQNSGLQNIQNISRVQPNSVGNTQPVMQHHQQTVLRQQRQQQQASIVHQQQVLSTQQQQQQPNTMGQQTSAINLQHNQLIGQQSSYSEMQQQQQSRLLGQQSNISNVQKLQHHSIGQHNNFSAVHQQQLGPQSSSTGQQQQQHQLFGTQSGSTTMVNNQHSAHLLQSKVSIPQQNQPTQGQRSQPELQQQVMPQLQTQSGQLQHQLNTKLQPNLSQWDMQQRLPTSGAFQQQNVIDQQKQLFQQQRAMPEASSTSSDSTAQTGNPNGGDWQEEVYQKINTFTVSSSGICNEEMGTGVLEKAFLPGKLKAMKDKYMPELNDMYQKIIGKLQQHDSLPQQPKGEQVEKLKMIKHVLERCMAFVQVPKSNITPNYKEKLGIYEKQIVNIISTHKRKPGVPPQQAQPLPPPHIHLTQENQMNPQMQSMNLQNNMGSLQHNSVLPSNAQQNMMSATQPTSNLDPGQNSTMNSLNINPLSSQGGMGMLQPNSSILQHQQLKQLPYRQMQQQYLHKQQLIQQQHQFQRQTKQQQQNGQLHMNQLPQLQPINDGNELKLRQQIGVKPEPLQQQQVASQRPAYHQQLKSGAPFSPQLLSASSPLTPQHSSPQIDQQNLLNSLTKSGTPLQSANSPFIVSSPSTTSTSHMPGESEKVNSGVSSLSNAGNIGHQPTGAVLPTQSLAIGTPGISASPLLAEFTSPDGNHGNGASVVSTKSSAIEQPIEHLLKVVKSISPKSLSASVSDIGSVVSMIDRIAGSAPGNGSRAAVGEDLVAMTKLHLQARTSGTPNGTRKMKRFTSAIPLNGVSSANSRRHPLLEEIRDINLGLIDTVVDISKEDADSAEGGKGTIVKCSFIASPIQPLRLLVPANYPNCSPILLDNKEYEDLSVKAQWRFGSCVRQLSEPMSLEEMVRTWDVCARTVISEYAQQSDGGTFSTKYGAWEDCLTLTGTAA
Length1190
PositionTail
OrganismCynara cardunculus var. scolymus (Globe artichoke) (Cynara scolymus)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> asterids> campanulids> Asterales> Asteraceae> Carduoideae> Cardueae> Carduinae> Cynara.
Aromaticity0.04
Grand average of hydropathy-0.668
Instability index60.74
Isoelectric point8.88
Molecular weight130371.63
Publications
PubMed=26786968

Function

Annotated function 
GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
chromatin DNA binding	GO:0031490	IEA:InterPro
transcription coactivator activity	GO:0003713	IEA:InterPro

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP06508
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             7|     552.50|      79|      80|     244|     322|       1
---------------------------------------------------------------------------
  139-  228 (78.40/21.86)	.............LIS.GSLEGanqtakemrlpevtsIRKFYEIFVI..SP....LSNMDIIVSHS........SQ.....G..........M..QQ.......VN..NQGQSLNHPqagQ.........QI....LP.PSIHNNIASSGGQG...SAGIS
  231-  319 (132.24/41.84)	LQPgsslsqstmpIIS.GQNSG...............LQNIQNISRV..QP..NSVGNTQPVMQHH........QQ.....T..........VLRQQ.......RQ..QQQASIVHQ...Q.........QV....LS.TQQQQQQPNTMGQQ...TSAIN
  320-  403 (93.08/27.31)	LQH........nqLI..GQQSS............yseMQQ.QQQSRLlgQQ..SNISNVQK.LQHH...............S..........I...........GQ..HNNFSAVHQ...Q.........QLgpqsSS.TGQQQQQHQLFGTQsgsTTMVN
  404-  444 (47.64/10.44)	NQH.......sahL.......................LQS..KVSIP..QQ..N.....QP....................T............QGQ.......RS..QPEL....Q...Q.........QV....M...PQLQTQ...............
  445-  512 (54.98/13.16)	...............S.GQ..................LQHQLN.TKL..QP..NL...SQWDMQQRlptsgafqQQ.....N..........VIDQQ.......KQlfQQQRAMPEA...S.........ST....SSdSTAQTGNPN.............
  679-  771 (80.45/22.62)	LQH.......nsvLPSnAQQNM...............MSATQPTSNL..DPgqNSTMNSLNINPLS........SQ.....GgmgmlqpnssILQHQqlkqlpyRQ..MQQQYL.HK...Q.........Q..........LIQQQHQ.FQRQ...TKQ..
  772-  846 (65.70/17.14)	.Q................QQNG...............QLHMNQLPQL..QP..INDGNELK.L..R........QQigvkpE..........PLQQQ.......QV..ASQRPAYHQ...QlksgapfspQL....LSaSSPLTPQHS.............
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      59.02|      16|      18|     613|     628|       2
---------------------------------------------------------------------------
  613-  628 (28.91/17.36)	NITPNYKEKLGIYEKQ
  631-  646 (30.11/18.39)	NIISTHKRKPGVPPQQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      50.38|      13|      17|       9|      21|       3
---------------------------------------------------------------------------
    9-   21 (25.37/13.95)	GDLPTAMDTSNWR
   28-   40 (25.01/13.66)	GGGDSSMESVDWR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      55.95|      18|      19|     862|     879|       5
---------------------------------------------------------------------------
  860-  877 (31.81/15.10)	TK....SGTPLQSANSPFIVSS
  878-  899 (24.15/ 9.60)	PSttstSHMPGESEKVNSGVSS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     125.93|      30|      75|     976|    1008|       8
---------------------------------------------------------------------------
  976- 1005 (48.12/30.39)	LSASVSDIGSVVSMIDRI.......AGSAPGNGSRAA
 1018- 1047 (45.24/30.68)	LQARTSGTPNGTRKMKRF.......TSAIPLNGVSSA
 1054- 1087 (32.58/16.14)	LLEEIRDIN..LGLIDTVvdiskedADSAEG.GKGTI
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP06508 with Med15 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) ISTHKRKPGVPPQQAQPLPPPHIHLTQENQMNPQMQSMNLQNNMGSLQHNSVLPSNAQQNMMSATQPTSNLDPGQNSTMNSLNINPLSSQGGMGMLQPNSSILQHQQLKQLPYRQMQQQYLHKQQLIQQQHQFQRQTKQQQQNGQLHMNQLPQLQPINDGNELKLRQQIGVKPEPLQQQQVASQRPAYHQQLKSGAPFSPQLLSASSPLTPQHSSPQIDQQNLLNSLTKSGT
2) LQSANSPFIVSSPSTTSTSHMPGESEKVNSGVSSLSNAGNIGHQPTGAVLPTQSL
3) NPIANSLQSNSAGNSANPSDPEKENIPLISGSL
4) QNSGLQNIQNISRVQPNSVGNTQPVMQHHQQTVLRQQRQQ
5) SHSSQGMQQVNNQGQSLNHPQAGQQILPPSIHNNIASSGGQGSAGISSALQPGSSLSQSTMPIIS
6) SIVHQQQVLSTQQQQQQPNTMGQQTSAINLQHNQLIGQQSSYSEMQQQQQSRLLGQQSNISNVQKLQHHSIGQHNNFSAVHQQQLGPQSSSTGQQQQQHQLFGTQSGSTTMVNNQHSAHLLQSKVSIPQQNQPTQGQRSQPELQQQVMPQLQTQSGQLQHQLNTKLQPNLSQWDMQQRLPTSGAFQQQNVIDQQKQLFQQQRAMPEASSTSSDSTAQTGNPNGGDWQEEVY
633
866
112
248
182
291
864
920
144
287
246
521










Molecular Recognition Features






MoRF SequenceStartStop




NANANA