<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP06507

Description "Protein kinase, ATP binding site-containing protein"
SequenceMEEEEPQKKMSNRGNNTGGGNNSNINSSNRPEWLQQYDLIGKIGEGTYGLVFLAKIKSNRSKSIAIKKFKQSKDGDGVSPTAIREIMLLREISHENVVKLVNVHINHMDMSLYLAFDYAEHDLYEIIRHHRDKVNQAINQYTVKSILWQLLNGLNYLHSNWIMHRDLKPSNILVMGDGEEQGVVKIADFGLARIYQAPLKALSDNGVVVTIWYRAPELLLGAKHYTSAVDMWAVGCIFAELLTLKPLFQGQEVKATPNPFQLDQLDKIFKVLGHPTVDKWPTLAHLPHWQSDQQHIQGHKYDSPGLYSVVHLSPKNPAYDLLSKMLEYDPRKRITAAQALEHDALVPSQPGEKIVNYPTRPVDTNTDFEGTTSLQPAQHASGNVSGAMGGPHVMPNRSVPRPMHMVGMQRMQQQSMAAYNIANQAGMGGAMNPGNIPMQRGVAAQPHQQQQQEGRNGDARISTTEIKAFLSLQQCIA
Length477
PositionKinase
OrganismCynara cardunculus var. scolymus (Globe artichoke) (Cynara scolymus)
KingdomViridiplantae
LineageEukaryota> Viridiplantae> Streptophyta> Embryophyta> Tracheophyta> Spermatophyta> Magnoliopsida> eudicotyledons> Gunneridae> Pentapetalae> asterids> campanulids> Asterales> Asteraceae> Carduoideae> Cardueae> Carduinae> Cynara.
Aromaticity0.07
Grand average of hydropathy-0.465
Instability index44.30
Isoelectric point8.28
Molecular weight53312.16
Publications
PubMed=26786968

Function

Annotated function 
GO - Cellular Component
GO - Biological Function
ATP binding	GO:0005524	IEA:UniProtKB-UniRule
protein serine/threonine kinase activity	GO:0004674	IEA:UniProtKB-KW

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP06507
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     129.71|      34|      35|     380|     414|       1
---------------------------------------------------------------------------
  351-  377 (27.84/12.37)	................GEKIVnyP.TRPVDTNTDFEGTTSLQPA
  380-  414 (61.11/40.91)	ASGNVS......GAMgGPHVM..P.NRSVPRPMHMVGMQRMQQQ
  417-  451 (40.76/21.80)	AAYNIAnqagmgGAM.NPGNI..PmQRGVAAQPH......QQQQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     166.18|      54|     129|      21|      81|       2
---------------------------------------------------------------------------
   21-   81 (80.17/63.17)	NNSNINSSNrpeWLQQYDL....IGKIGEG.TYGLVFLAKIKSNRsksIAIKKFKQSKDgDGVSPT
  152-  210 (86.01/48.97)	NGLNYLHSN...WIMHRDLkpsnILVMGDGeEQGVVKIADFGLAR...IYQAPLKALSD.NGVVVT
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP06507 with CDK8 domain of Kingdom Viridiplantae


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) AQALEHDALVPSQPGEKIVNYPTRPVDTNTDFEGTTSLQPAQHASGNVSGAMGGPHVMPNRSVPRPMHMVGMQRMQQQSMAAYNIANQAGMGGAMNPGNIPMQRGVAAQPHQQQQQEGRNGDARISTT
337
464










Molecular Recognition Features






MoRF SequenceStartStop




1) KSIAIKKFK
62
70