<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP06492
Description |
Mediator of RNA polymerase II transcription subunit 16 |
Sequence | MTATQAGILLSTYSACQKMCLYRVHISWNPAQWEPAQGKPPGQFPIPTFRLIHCKVDMPSNILNINRGPDHSDQSLPFLNSVYSLTRLEIMPGQFDSPAGSTANPWILAVLSKPLHAIHDYPDQQGPPSVIVRWHLESAPQILHPKFDEVTSKKNNAQAKPKMELRRLEDVYCDKYIVSVDLIEHGTVLAVSHDDSSITCYDTRTMTVLNGLDDSTTVTCLAQAGFQYPLETSGMPGTDRSCFQRRG |
Length | 247 |
Position | Tail |
Organism | Penicillium freii |
Kingdom | Fungi |
Lineage | Eukaryota> Fungi> Dikarya> Ascomycota> Pezizomycotina> Eurotiomycetes>
Eurotiomycetidae> Eurotiales> Aspergillaceae> Penicillium.
|
Aromaticity | 0.08 |
Grand average of hydropathy | -0.326 |
Instability index | 56.22 |
Isoelectric point | 6.29 |
Molecular weight | 27524.04 |
Publications | |
Function
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery. Mediator is recruited to promoters by direct
interactions with regulatory proteins and serves as a scaffold for the
assembly of a functional preinitiation complex with RNA polymerase II
and the general transcription factors.
ECO:0000256 RuleBase:RU364149
|
GO - Cellular Component | mediator complex GO:0016592 IEA:InterPro
|
GO - Biological Function | |
GO - Biological Process | |
Interaction
Repeat regions
Repeats |
>MDP06492
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 137.53| 41| 50| 41| 90| 1
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41- 89 (62.87/45.93) PGQFPIPTFRLIHckvdmPsNILNINRGP.....DHSDQSLPflNSVYSLTRLE
92- 137 (74.66/32.28) PGQFDSPAGSTAN.....P.WILAVLSKPlhaihDYPDQQGP..PSVIVRWHLE
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 50.09| 14| 18| 187| 200| 2
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187- 200 (24.99/16.15) TVLAVSHDDSSITC
207- 220 (25.10/16.24) TVLNGLDDSTTVTC
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