<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP06482
Description |
Mediator of RNA polymerase II transcription subunit 16 |
Sequence | MPLMMDDSINVDDLFGEPTSLELGLPPSASSARGLAQRLDEMRLLGCCQKIAWSKLGCIAYISQDSLRVKVRHLQCRPSDGKWVLSDETPLMPITEAHGGHALTHLSWNEAGSDLAVVDVTGRVSVYHIPFALNSVNGLRQPAFSPDDGSQIVGMMWLNTQRSVHAFYQAAKVQGRWAYSPFRRRPIGPFHPANKAALLCITRSGSMKLLYQNPDGRWDDISVDLKSTSYSDRLLSHAALVATQNGILIATYSICQKIRFYRVQINWNPPQWDPAQQPKQTPPQFPVPSFRFTHSKVETSCTVPGMPRNDGEEPDMMQQSVSNPLYSLSRLDIILPASDNAAGTTANPWIVAVFSTPPQATPDHPGPQGPASVIVRWQLDTAAFTLHPKFDEMATKRNSTQMKPRPVLRRLEDIYSDRYVISVDQIEYGNVVAITYDDSSVSFYDPKTMALFNGVDDANTVTGLAQAGFHYAPDASGQGQHVSFSPSACAAVMLDNDGQTHLRVMEHSYGAENGLYDENKFSAAIASLTLAFCRGCGSEVNTDDILLILIQQLSQDAQITFINEVYRALPINCNFTVEQEKLMNHPYIPKCLSIQAALGFANKYKPRSFASSVSWSILQLRHAAILYPFFFQYNKGIQAEPHDPDVLRMMLGNTRWALDFSLYILNELFDLADEFESVSADQEAFSQKLKTTNSLALIILLSSMSRAFLRFICRGLRGIHAGYTNASLAGDSRLQYAEICQALDATPARIDVYEKFLSAVDSAVRHAYHGAGFGDTERPGPEKELLVNARIPPVLVAAVSTILRQTVPGLKSDVDRMAIYMHDYSWLGFGSDRRSELYRRTREVDIIKKTPIRMTIAQGSNGPQLGKQNSQGVLRRRCVRCCDVSEGTYPPRSVLAFRMIFKLGHLRSCICGGMWTLESGLNEVGK |
Length | 926 |
Position | Tail |
Organism | Aspergillus niger |
Kingdom | Fungi |
Lineage | Eukaryota> Fungi> Dikarya> Ascomycota> Pezizomycotina> Eurotiomycetes>
Eurotiomycetidae> Eurotiales> Aspergillaceae> Aspergillus>
Aspergillus subgen. Circumdati.
|
Aromaticity | 0.09 |
Grand average of hydropathy | -0.206 |
Instability index | 44.97 |
Isoelectric point | 6.90 |
Molecular weight | 102844.04 |
Publications | PubMed=26893421
|
Function
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery. Mediator is recruited to promoters by direct
interactions with regulatory proteins and serves as a scaffold for the
assembly of a functional preinitiation complex with RNA polymerase II
and the general transcription factors.
ECO:0000256 RuleBase:RU364149
|
GO - Cellular Component | mediator complex GO:0016592 IEA:InterPro
|
GO - Biological Function | |
GO - Biological Process | |
Interaction
Repeat regions
Repeats |
>MDP06482
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No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level
2| 132.17| 37| 40| 139| 177| 1
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139- 177 (63.68/51.46) LRQPAFSPDDGSQIVGMMWLNTQRSVHAFYQAAkvQGRW
182- 218 (68.49/48.88) FRRRPIGPFHPANKAALLCITRSGSMKLLYQNP..DGRW
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