<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP06458

Description Uncharacterized protein
SequenceMNQVPVAATHNERTNIIPDGNWRSTLTASEQHAIIFHLVSALRAVSSNVSLEHLVAIVNAFEKHAYEKANSKMEYINICNTKLMHIKGTAIAKHSSLQTQNQQPIVHFFPQVHHQQVVSSQPKTFERSQGSGLISQAAFARSASQSSQQAIDSHSQFQQAATLLNPQMVFHQKQALMRQASTNSHLSTQNLMQSLNCSVNQQSLNVNSASDNLKFPSHSVSQQKALQIQQILNQLRAQNNQQQYSQYMTRQTHAFQSSDKHQPSLNQQSLNQQQIHMLSQADLYQQCSDGSLLNPSNINLQKLMALNQTIQTQNQNKKPQSSQSQAKQLLSGQTLQGFSSQMQGSVQQMVNPQVQKRVTQTTGPSTSHQEFKKYLDPHLNPCNYLIPQRILAQLPELPSNVSTWTQVAELFRSQRLSPEQMTRVHDLFYQHALYLQLHYQQIQQMNNQSANQFQSQSMSQLHSTKPASQIQQQQMRQSLPQMQQASNVIPSEFMQSEWFSEAPNFSSYSHVFVPNINTSLNNQVSQSQFQSIDQLLTTTKNDNAFGAKKRPKTPVKIKKKEDIKSVNDQHYVLQASNLVLSSPVPTQQITQFKQDSTPQDQSDNSIVQKILMCGGKEVNIQMVARLKRIQNEVERNGIKITPLNDLTSIQKQQVCELVTEMNQMYHRIDMLLPLFMALSSNESAVKQLLQMRLLCKNQFDVLPQGIYLCYPSQFIKIKKIILEYFKFVKSSVHAIQKQIENEKPLSDKTPTNLPEINSSISDFQHALVDTVSVQIPSDASSSKLFKTNLKNNTKTDNMEMISRDNFNIDNNFSETNTISGENILSSEKINLDVFDLSKESHESQIKDKVINDSLDYTLLNVASVLEADDVNEIFFMDKSFLNEKESIDILSNELDSEIISSLEVKSPQSFVTNGLPDQSLGKDQNDFVGISGIDDKLSSSLTVSPVSNEKRSFSSSEAVFSSIVSNVLEDEKLLNDINFDQCFDLTFNDKTYGNNILNFDKLQENNLSSVFDINEIKLENTPEGLEWDFRSISNIGPFKIKDFYASNNENIWNEEVKTRDLSTLGLGIVTNVY
Length1073
PositionTail
OrganismPneumocystis jirovecii (strain RU7) (Human pneumocystis pneumonia agent)
KingdomFungi
LineageEukaryota> Fungi> Dikarya> Ascomycota> Taphrinomycotina> Pneumocystidomycetes> Pneumocystidaceae> Pneumocystis.
Aromaticity0.07
Grand average of hydropathy-0.551
Instability index50.40
Isoelectric point6.25
Molecular weight121450.89
Publications
PubMed=26899007

Function

Annotated function 
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP06458
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             6|     688.46|     104|     105|     148|     251|       1
---------------------------------------------------------------------------
   34-  121 (84.62/38.95)	................................IIFHLVSA.L.RAV..SSN..VSLEHL.VAI.VNAFEKH...AYEK...ANSKMEYINICNTKLMHIKGT.......AIAK.HSSLQTQNQQPivhffpqvHHQQ.VVSSQ
  148-  251 (172.44/87.88)	Q..QAI.DSH..SQFQQ.......AATLLNPQMVFHQKQA.LMRQA..STNSHLSTQNL.MQS.LNCSVNQ...QSLN...VNSASDNLKFPSHSVSQQKAL.......QIQQILNQLRAQNNQQ........QYSQ.YMTRQ
  253-  353 (119.50/58.39)	HafQSS.DKHqpSLNQQ.......S...LNQQQIHMLSQAdLYQQC..SDGSLLNPSNInLQK.L.MALNQ......T...IQTQNQNKK.PQSSQSQAKQL.......LSGQTLQGFSSQ.MQG........SVQQ.MVNPQ
  363-  466 (111.67/54.02)	G..PS..TSH..QEFKKyldphlnPCNYLIPQRILAQLPE.L........PSNVSTWTQ.VAE.LFRS......QRL........SPEQMTRVHDLFYQHALylqlhyqQIQQMNNQSANQFQSQ........SMSQlHSTKP
  472-  571 (104.38/49.97)	Q..QQMrQSL..PQMQQ.......ASNVI.PSE.FMQSEW.FSEAPnfSSYSHVFVPNI.NTS.LNNQVSQsqfQSIDqllTTTKNDN.AFGAKK.RPKTPV.......KIKK.KEDIKSVND.Q........HY........
  573-  659 (95.84/45.21)	...............LQ.......ASNLVLSSPVPTQQIT.QFKQD..STPQDQSDNSI.VQKiLMCG..G...KEVN...IQMVA.RLKRIQNEV.ERNGI.......KITP.LNDL.TSIQKQ........QVCE.LVT..
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             5|     185.53|      37|      37|     875|     911|       2
---------------------------------------------------------------------------
  808-  845 (33.70/15.01)	.IDNNF.SETNTI.....sgeNILS.SEKINLDVFDLSKESHESQI
  875-  911 (59.50/32.14)	FMDKSFLNEKESI........DILS.NELDSEIISSLEVKSPQSFV
  915-  946 (38.34/18.09)	LPDQSLGKDQN..........DFVGiSGIDDKLSSSLTV.SP...V
  947-  984 (32.87/14.45)	S......NEKRSFssseavfsSIVS.NVLEDEKLLN.DINFDQCFD
  987- 1009 (21.11/ 6.64)	FNDKTYGN.............NILNfDKLQENNLSS..........
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     107.38|      35|      38|     716|     753|       3
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  716-  753 (51.21/39.45)	KIKKIILEyfkFVKSSVHAIQKQIENEKPLSDKTPTNL
  755-  789 (56.17/34.41)	EINSSISD...FQHALVDTVSVQIPSDASSSKLFKTNL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      72.01|      24|      28|    1011|    1036|       5
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 1011- 1036 (34.14/30.94)	FDINEIKLENTpEGLeWD....FRSISNIG
 1038- 1065 (37.88/23.43)	FKIKDFYASNN.ENI.WNeevkTRDLSTLG
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP06458 with Med15 domain of Kingdom Fungi
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