Description | Mediator of RNA polymerase II transcription subunit 11 |
Sequence | MDPPPDSVPRPQAEPSPGEIDPIWTTSRTARQIYSLGEVEKDIGRLLYLAASSISLLTLPQTDGPNDNLPQGEERSEQFVLEVSEYFERLDAIQLAIRSSLAHIRHSRIAPSAINAPPPGFLPPSLGVQLPGSSSEGARSNRGLQESRVERDAWKGILDALTRMKEAIEKEGSEQTQAQTQTRNEAASSMDMQGVEQS |
Length | 198 |
Position | Head |
Organism | Moniliophthora roreri |
Kingdom | Fungi |
Lineage | Eukaryota> Fungi> Dikarya> Basidiomycota> Agaricomycotina> Agaricomycetes> Agaricomycetidae> Agaricales> Marasmiaceae> Moniliophthora. |
Aromaticity | 0.04 |
Grand average of hydropathy | -0.624 |
Instability index | 63.92 |
Isoelectric point | 4.75 |
Molecular weight | 21643.80 |
Publications |
Annotated function |
Component of the Mediator complex, a coactivator involved in
the regulated transcription of nearly all RNA polymerase II-dependent
genes. Mediator functions as a bridge to convey information from gene-
specific regulatory proteins to the basal RNA polymerase II
transcription machinery. Mediator is recruited to promoters by direct
interactions with regulatory proteins and serves as a scaffold for the
assembly of a functional preinitiation complex with RNA polymerase II
and the general transcription factors.
ECO:0000256 RuleBase:RU364147 |
GO - Cellular Component | mediator complex GO:0016592 IEA:InterPro |
GO - Biological Function | transcription coregulator activity GO:0003712 IEA:InterPro |
GO - Biological Process | regulation of transcription by RNA polymerase II GO:0006357 IEA:InterPro |
Binary Interactions |
Repeats | >MDP06436 --------------------------------------------------------------------------- No. of Repeats|Total Score|Length |Diagonal| BW-From| BW-To| Level 2| 65.33| 22| 107| 15| 42| 1 --------------------------------------------------------------------------- 15- 42 (34.86/33.18) PS.....PGeidpiwTTSRTARQIYSLGE..VEKD 124- 152 (30.48/15.71) PSlgvqlPG......SSSEGARSNRGLQEsrVERD --------------------------------------------------------------------------- |
MoRF Sequence | Start | Stop |
1) GEIDPIWTTSRTA 2) LTRMKEAIEKE | 18 161 | 30 171 |
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