<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP06421

Description Coiled-coil domain-containing protein 47
SequenceMMESRDVLYATPYRPKSSAAHVFESIKPTPLLNITPECSEDDDSNSGTSEKSSDKTLKREIADSSLHSCYHGKQLNRPFLNTCEAIIEKIKRVKKIDPSTLAKEQIRRNEHYYQKIAMKKENARSIVQNIKSIQSSISEVLAKLQMVDQPSLLNSFRVISSQFNSMLQLLRSDRASHFKNYVFLPIKLSVEVDADLEAATENRLHAWTHAVVPDYLRTKPDPQVEQKDQQISNQVQQRICNPESLQKQITAFNRCLNCILDSLNASIRDSEMDGRKTSKTSDGEDTALLVAAILKGQNVKPAYSATPASSRGSSGDSGHSKASKAQQVQCCFILKKQCMAKNKCSININQFTTERRKTCIWMFFLSCLFEFVELSVKQVSQIDDNEFAEFEEFDVELDASVDADFTANNVNERETPPVDTASIGAKRSPAYAEQKRNDAPNNNFNDDDYGIVEDESVDDFSHLLDENEFENFPDERRPGKQNAGPSKTVTQLKITDTKNHSLAVAWFDSNRPFLEENFSIVGDDGISPEVTKNVLIKESDNHYIVWCSGRQGCIGMEIHLKLIKRQDLLSLIFYIIRPKFDVIEIKIILNPEEMDPFVFALGTKRSAIKNSKEIMDLNLYCSEKKNVEKLGLPSSYILHSEIGEVTTGLIDTKIVSALCKYKDVVDYIHISDQFVGIKPIEMENMTKPPETAKVVMICLNIPGQLRATEEDVSSLQPLMIFIFHVLEKVRRFRLTREGKQKADKNRQYVEESFLKTTHAQRQEAAQQRREERARERKERLMAEEDPERQRKLEKQELKRELKKKQPRVKQIKIKAMLRFLIKAKQIHC
Length828
PositionHead
OrganismTrichinella sp. T8
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Nematoda> Enoplea> Dorylaimia> Trichinellida> Trichinellidae> Trichinella> unclassified Trichinella.
Aromaticity0.07
Grand average of hydropathy-0.584
Instability index48.76
Isoelectric point7.49
Molecular weight94665.79
Publications









Function






Annotated function


GO - Cellular Component
integral component of membrane	GO:0016021	IEA:UniProtKB-KW
mediator complex	GO:0016592	IEA:InterPro
rough endoplasmic reticulum membrane	GO:0030867	IEA:UniProtKB-SubCell

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP06421
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      65.98|      21|      38|      86|     106|       1
---------------------------------------------------------------------------
   86-  106 (33.18/21.74)	IIEKIKRVKKIDPSTLAKEQI
  126-  146 (32.80/21.41)	IVQNIKSIQSSISEVLAKLQM
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     120.45|      37|      38|     455|     491|       2
---------------------------------------------------------------------------
  455-  491 (65.10/44.46)	ESVDDFSHLLDENEFE.NFP..DERRPGKQNAGPSKTVTQ
  493-  532 (55.34/36.64)	KITDTKNHSLAVAWFDsNRPflEENFSIVGDDGISPEVTK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     176.91|      55|     206|     178|     234|       3
---------------------------------------------------------------------------
  178-  234 (88.77/66.86)	FKNYVFLPIKLSVEVDADLEAATENRLHawTHAVVPDYLRTKPDPQ.VEQKDQQISNQ
  387-  442 (88.14/58.82)	FAEFEEFDVELDASVDADFTANNVNERE..TPPVDTASIGAKRSPAyAEQKRNDAPNN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     138.20|      36|      36|     624|     659|       5
---------------------------------------------------------------------------
  601-  621 (26.59/13.47)	......LGTKRSAIKNSK...EI....MDLNL...YC
  624-  659 (57.34/36.82)	KKNVEKLGLPSSYILHSEI.GEVTTGLIDTKIVSALC
  662-  698 (54.27/34.48)	KDVVDYIHISDQFVGIKPIeMENMTKPPETAKVVMIC
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      89.75|      27|     270|      24|      52|       7
---------------------------------------------------------------------------
   24-   52 (42.65/35.22)	ESIKPTplLNITPECSEDDDSNSGTSEKS
  297-  323 (47.10/31.48)	QNVKPA..YSATPASSRGSSGDSGHSKAS
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP06421 with Med8 domain of Kingdom Metazoa
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