<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP06408

Description Ectonucleoside triphosphate diphosphohydrolase 1
SequenceMDEGRKNINARKAMLLKEYQVLLQRSVKSIRENFTEIIRMAKVGEEGQVSRLTEYEHELFEMQIRAANMTHAAEALIKMVTDLKQFLILNDFAYINESITTTAVHSQIAQREFRDKLIAVKEEMTFYLQEAEQEYYNTAINMTLDEFGTELYVDPWQTFVSIKGKLRKRAFRSPNLAEVVKDYDALASRLLDENCTEYSALCRMNMAKCKNQLGNTDQEAVEYRTAGRLYIRAEKEKESVENRLSMECLYMAMHCYNEAIRLHLSQGQKLLAASLLIELGKELACMQHPEDAIQNFEKAIHLLDTHPHAVGHALRWKLCVETSVGFLADARRTSNFYRQIVESWPNSGFRKLHLNELEIITVMLLLALKPIKSEMNDFEKRVLQRYSDETDEALLSSYEGSLLPNDSYIISVEIYLHLKSFVLAINNNDPSAADIALTAIHHRNVKLVHSAGADASLPLRVFIKSLFYNESSVSLEVDSDFKVRDVINAYAYRTGHSEKDEEFVLRFHDHSSLNSEDVLHVLGIYNDEELIISVRGEDSRRSRNSWWWLGSVALLISLVGLTAVSVLFALSGDLPDEFGIIIDAGSSHSGLYIYTWNGRKNKTGVIKQYAPSCSTEDGISSFTDNPTDAGNSLIFCLNNASATVPSKRHSSTAMYLAATAGMRILEIRDPLSSCKIINAVSNTMHSYNFLFKNASIISGIDEGIYGWITLNFLSHRLMNSASKLNDIRPLTIGAMDLGGASTQIIFEINSSEFTERNYSLKLFGETYNLFVDSYLCCGANEVQRIIQAQIVAEDTTNQQPLHPCLPLNYTMNVTSEQIFLMPCSLNQKPNNVLPNYVFRGSSDPHSCLKKIRYMLDTSACSVKKAKIPKPRGEFMAFSGMYWTAKFFNCTSGCSYNKFFENVQNYCEKSWSSIEAAAYPYKKTFLSTYCFTGLYSLTLFKDAYHFSDAQIQKIEFVNEIDSTEIGWTLGFMLNATNQLPEEQPIEHIGLIEAGKGDG
Length997
PositionHead
OrganismTrichinella sp. T8
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Nematoda> Enoplea> Dorylaimia> Trichinellida> Trichinellidae> Trichinella> unclassified Trichinella.
Aromaticity0.10
Grand average of hydropathy-0.213
Instability index35.71
Isoelectric point5.69
Molecular weight112925.26
Publications









Function






Annotated function


GO - Cellular Component
integral component of membrane	GO:0016021	IEA:UniProtKB-KW
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
ATP binding	GO:0005524	IEA:UniProtKB-KW
hydrolase activity	GO:0016787	IEA:UniProtKB-KW
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP06408
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     169.63|      53|     253|     681|     738|       1
---------------------------------------------------------------------------
  681-  738 (85.88/79.20)	SNTMHSYNFLFKNASI.....ISGIDEGIYGWiTLNFlshrLMNSASKLNDIRPLT.IGAMDLG
  935-  993 (83.75/61.45)	SLTLFKDAYHFSDAQIqkiefVNEIDSTEIGW.TLGF....MLNATNQLPEEQPIEhIGLIEAG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     123.44|      43|     253|     117|     171|       2
---------------------------------------------------------------------------
   94-  150 (55.15/57.95)	YINESITTTAVHSQIAQREFrdkLIAvkeemtfylqEAEQEYYNTAINMtLDEFGTE
  152-  197 (68.29/39.42)	YVDPWQTFVSIKGKLRKRAFrspNLA..........EVVKDYDALASRL.LDENCTE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     129.59|      40|     253|     300|     344|       3
---------------------------------------------------------------------------
  300-  344 (65.91/47.06)	IHLLDTHPHAVGHALRWKLCVEtsVGFLADARRT.SNFYrqiVESW
  556-  596 (63.69/33.95)	ISLVGLTAVSVLFALSGDLPDE..FGIIIDAGSShSGLY...IYTW
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      86.07|      24|      24|     500|     523|       4
---------------------------------------------------------------------------
  500-  523 (41.29/24.16)	DEEFVLRFHDHSSLNSEDVLHVLG
  527-  550 (44.78/26.77)	DEELIISVRGEDSRRSRNSWWWLG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      62.49|      19|      22|     450|     468|       7
---------------------------------------------------------------------------
  450-  468 (31.20/26.31)	SAGADASLPLRVFIKSLFY
  474-  492 (31.28/26.40)	SLEVDSDFKVRDVINAYAY
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP06408 with Med22 domain of Kingdom Metazoa
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