<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP06407

Description RNA polymerase II-associated protein 3
SequenceMAKLMKENFPPDRERVVTKTSELQITLIPTHNKKSASLILCLSTELDCLRILQLTVVMQSFIFIEFHDKNSNEAPQRIEELIGELQQLRKDIRLCFRGVDCSPEEQVHRVRVLYKELLLKDRLVKHLKQISVQLVNVQVNDSKLLNEEVFKIPDLLDVGPSTEKASSSNNNNGKKLSLSCPKCSCIILRENHGEQVTVEKELPELSLKADGTVDMKTFTEFVRVDDIYDFENIGFSRDSNGVQYLLCAACEIGPLVMLVRKERKDISEKDAQKALFEKESGNSFYVKKDYEKAIMCYSRSISADPFRPVVYCNRAMAYLKLKNYAEAYADCSKALTFDSTYVKALYRRGMASKGLNNFDDAVEDFQHVLTLDPNNDIAKKELEEIISKVKPAENDPLLVYPVENPDEKEYQKPLKVIIVRDAVKKSHFNSQQPALSDESNVTKQSEQKISDYKLNASIKITRIPKCYAELRADWISIKEEPLALADYILNIPCDCFSNLLGEFLDGEFVANLLKAFMIKVNSEPQCSISYLKTVLDKAKHVCSKDQVQRWDDLFKKHIETAINKNDNEEEASVESFPKFYPTRPEQVPSGSKNISTMV
Length598
PositionMiddle
OrganismTrichinella sp. T8
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Nematoda> Enoplea> Dorylaimia> Trichinellida> Trichinellidae> Trichinella> unclassified Trichinella.
Aromaticity0.08
Grand average of hydropathy-0.408
Instability index41.44
Isoelectric point5.91
Molecular weight68264.57
Publications









Function






Annotated function


GO - Cellular Component
GO - Biological Function
guanyl-nucleotide exchange factor activity	GO:0005085	IEA:UniProtKB-KW

GO - Biological Process
protein transport	GO:0015031	IEA:UniProtKB-KW
small GTPase mediated signal transduction	GO:0007264	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP06407
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      99.24|      31|      32|     285|     316|       1
---------------------------------------------------------------------------
  285-  316 (52.70/44.75)	YVK.KDYEKAIMCYSRSISAD.PFRPVVYcNRAM
  318-  350 (46.54/32.80)	YLKlKNYAEAYADCSKALTFDsTYVKALY.RRGM
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     462.37|     154|     423|       6|     171|       2
---------------------------------------------------------------------------
    6-  171 (231.25/181.92)	KENFPPDR.....ERVVTKTSELQITLIPTHNK.KSASLILCLStEL..DCLRILQLTVVMQSFIFIEFHDKNSNEAPQRIE.ELIGELqqlrkdIRLCFRGVDCSPEEQVHRVR.VL..YKELLLKDRlVKHLKQISVQLVNVQVNDSKllNEE...VFKIPDLLDVGPstEKASSSNNN
  425-  593 (231.12/150.93)	KSHFNSQQpalsdESNVTKQSEQKISDYKLNASiKITRIPKCYA.ELraDWISIKEEPLALADYILNIPCDCFSNLLGEFLDgEFVANL......LKAFMIKVNSEPQCSISYLKtVLdkAKHVCSKDQ.VQRWDDLFKKHIETAINKND..NEEeasVESFPKFYPTRP..EQVPSGSKN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      97.58|      28|     171|     205|     232|       3
---------------------------------------------------------------------------
  205-  232 (47.05/37.54)	LSLKADGTVDMKTFTEFV.RVDD.......IYDFEN
  353-  367 (16.90/ 8.08)	...........KGLNNF...DDA.......VEDFQH
  369-  404 (33.64/24.44)	LTLDPNNDIAKKELEEIIsKVKPaendpllVYPVEN
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP06407 with Med9 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




NANANA









Molecular Recognition Features






MoRF SequenceStartStop




1) VESFPKFYPTRPE
573
585