<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP06407

Description RNA polymerase II-associated protein 3
SequenceMAKLMKENFPPDRERVVTKTSELQITLIPTHNKKSASLILCLSTELDCLRILQLTVVMQSFIFIEFHDKNSNEAPQRIEELIGELQQLRKDIRLCFRGVDCSPEEQVHRVRVLYKELLLKDRLVKHLKQISVQLVNVQVNDSKLLNEEVFKIPDLLDVGPSTEKASSSNNNNGKKLSLSCPKCSCIILRENHGEQVTVEKELPELSLKADGTVDMKTFTEFVRVDDIYDFENIGFSRDSNGVQYLLCAACEIGPLVMLVRKERKDISEKDAQKALFEKESGNSFYVKKDYEKAIMCYSRSISADPFRPVVYCNRAMAYLKLKNYAEAYADCSKALTFDSTYVKALYRRGMASKGLNNFDDAVEDFQHVLTLDPNNDIAKKELEEIISKVKPAENDPLLVYPVENPDEKEYQKPLKVIIVRDAVKKSHFNSQQPALSDESNVTKQSEQKISDYKLNASIKITRIPKCYAELRADWISIKEEPLALADYILNIPCDCFSNLLGEFLDGEFVANLLKAFMIKVNSEPQCSISYLKTVLDKAKHVCSKDQVQRWDDLFKKHIETAINKNDNEEEASVESFPKFYPTRPEQVPSGSKNISTMV
Length598
PositionMiddle
OrganismTrichinella sp. T8
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Nematoda> Enoplea> Dorylaimia> Trichinellida> Trichinellidae> Trichinella> unclassified Trichinella.
Aromaticity0.08
Grand average of hydropathy-0.408
Instability index41.44
Isoelectric point5.91
Molecular weight68264.57
Publications









Function






Annotated function


GO - Cellular Component
GO - Biological Function
guanyl-nucleotide exchange factor activity	GO:0005085	IEA:UniProtKB-KW

GO - Biological Process
protein transport	GO:0015031	IEA:UniProtKB-KW
small GTPase mediated signal transduction	GO:0007264	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP06407
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      99.24|      31|      32|     285|     316|       1
---------------------------------------------------------------------------
  285-  316 (52.70/44.75)	YVK.KDYEKAIMCYSRSISAD.PFRPVVYcNRAM
  318-  350 (46.54/32.80)	YLKlKNYAEAYADCSKALTFDsTYVKALY.RRGM
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     462.37|     154|     423|       6|     171|       2
---------------------------------------------------------------------------
    6-  171 (231.25/181.92)	KENFPPDR.....ERVVTKTSELQITLIPTHNK.KSASLILCLStEL..DCLRILQLTVVMQSFIFIEFHDKNSNEAPQRIE.ELIGELqqlrkdIRLCFRGVDCSPEEQVHRVR.VL..YKELLLKDRlVKHLKQISVQLVNVQVNDSKllNEE...VFKIPDLLDVGPstEKASSSNNN
  425-  593 (231.12/150.93)	KSHFNSQQpalsdESNVTKQSEQKISDYKLNASiKITRIPKCYA.ELraDWISIKEEPLALADYILNIPCDCFSNLLGEFLDgEFVANL......LKAFMIKVNSEPQCSISYLKtVLdkAKHVCSKDQ.VQRWDDLFKKHIETAINKND..NEEeasVESFPKFYPTRP..EQVPSGSKN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      97.58|      28|     171|     205|     232|       3
---------------------------------------------------------------------------
  205-  232 (47.05/37.54)	LSLKADGTVDMKTFTEFV.RVDD.......IYDFEN
  353-  367 (16.90/ 8.08)	...........KGLNNF...DDA.......VEDFQH
  369-  404 (33.64/24.44)	LTLDPNNDIAKKELEEIIsKVKPaendpllVYPVEN
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP06407 with Med9 domain of Kingdom Metazoa
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