<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP06405

Description RNA polymerase II-associated protein 3
SequenceMAKLMKENFPPDRERVVTKTSELQITLIPTHNKKSASLILCLSTELDCLRILQLTVVMQSFIFIEFHDKNSNEAPQRIEELIGELQQLRKDIRLCFRGVDCSPEEQVHRVRVLYKELLLKDRLVKHLKQISVQLVNVQVNDSKLLNEEVFKIPDLLDVGPSTEKASSSNNNNGKKLSLSCPKCSCIILRENHGEQVTVEKELPELSLKADGTVDMKTFTEFVRVDDIYDFENIGFSRDSNGVQYLLCAACEIGPLVMLVRKERKDISEKDAQKALFEKESGNSFYVKKDYEKAIMCYSRSISADPFRPVVYCNRAMAYLKLKNYAEAYADCSKALTFDSTYVKALYRRGMASKGLNNFDDAVEDFQHVLTLDPNNDIAKKELEEIISKVKPAENDPLLVYPVENPDEKEYQKPLKVIIVRDAVKKSHFNSQQPALSDESNVTKQSEQKISDYKLNASIKITRIPKCYAELRADWISIKEEPLALADYILNIPCDCFSNLLGEFLDGEFVANLLKAFMIKVNSEPQCSISCMERLELIGKAKRFDIVVLFLSHLKTVLDKAKHVCSKDQVQRWDDLFKKHIETAINKNDNEEEASVESFPKFYPTRPEQVPSGSKNISTMV
Length620
PositionMiddle
OrganismTrichinella sp. T8
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Nematoda> Enoplea> Dorylaimia> Trichinellida> Trichinellidae> Trichinella> unclassified Trichinella.
Aromaticity0.07
Grand average of hydropathy-0.370
Instability index41.83
Isoelectric point6.07
Molecular weight70801.66
Publications









Function






Annotated function


GO - Cellular Component
GO - Biological Function
guanyl-nucleotide exchange factor activity	GO:0005085	IEA:UniProtKB-KW

GO - Biological Process
protein transport	GO:0015031	IEA:UniProtKB-KW
small GTPase mediated signal transduction	GO:0007264	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP06405
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      99.24|      31|      32|     285|     316|       1
---------------------------------------------------------------------------
  285-  316 (52.70/49.62)	YVK.KDYEKAIMCYSRSISAD.PFRPVVYcNRAM
  318-  350 (46.54/36.43)	YLKlKNYAEAYADCSKALTFDsTYVKALY.RRGM
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     480.53|     160|     423|       6|     182|       2
---------------------------------------------------------------------------
    6-  182 (237.25/228.55)	KENFPPDR.....ERVVTKTSELQITLIPTHNK.KSASLILCLStEL..DCLRILQLTVVMQSFIFIEFHDKNSNEAPQRIE.ELIGELqqlrkdIRLCFRGVDCSPEEQVHRVRVLykELLLK....DRLV...KHLKQIsvqLVNVQVNDSKllnEEVFKIPDLLDvgPSTEKASSSNNNNGKKLSLSCPK
  425-  600 (243.29/184.82)	KSHFNSQQpalsdESNVTKQSEQKISDYKLNASiKITRIPKCYA.ELraDWISIKEEPLALADYILNIPCDCFSNLLGEFLDgEFVANL......LKAFMIKVNSEPQCSISCMERL..ELIGKakrfDIVVlflSHLKTV...LDKAKHVCSK...DQVQRWDDLFK..KHIETAINKNDNEEEASVESFPK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      58.55|      19|      31|     372|     390|       5
---------------------------------------------------------------------------
  372-  390 (30.97/16.03)	DPNNDIAKKELEEIISK..VK
  404-  424 (27.58/13.62)	NPDEKEYQKPLKVIIVRdaVK
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP06405 with Med9 domain of Kingdom Metazoa
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