<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP06396

Description Mediator of RNA polymerase II transcription subunit 17
SequenceMARRQFPNSKSDWLVMTPSHASANKIKEASILIMRNLFVTKIHSFLQFSTFIFLFSALRLIFAMNSGDAEDEEEQKLLVAVEPLREWKVFDISFSGVERYLQPLHYNDHVAELAHNVRWSKLVGKSSRNLSTISSTTKADDPTSSRAAWENVARSLHSALTEMVVLMDLIKVTMTGRYMAFDAAMHEMSDDSKPMFKSGDAYALFAKRKALSITSNVLLDFVGKQKVKLSGIGSIQQAMQPDEESTYLREMAEMRKYWRLRKSKNSILGDLSLGHCTFVCLCMVSCLHLLLYVCMLESGCRRFERKSTVEDTFNNWQAFPQVGSVYTSGRFEFNSVGIDIQADRHLEGQVGSGSVIDAVSRFVFIGIRQFYANQAQAISKEAIVYHNNTSFIYKDFIMIRLDSSNAVLVSLFSREELEEARKNMPKDKSAKRLIAETKLQCIFALKQRVCSRYMYLIDMVGNFVSTKPITAPLIIQTHPAPLAGVEMKSQEQIEHLEECQPSFILHNILDDARHYILITEMKKALDQLSSAQKDPVMTVYWCYDCCRYNTIARLSLVIPFYEYCGSLLRILYPLDSDQVQVFLLKIDGENPSWDNWQNCTPDAYVPIDLNSMAVDGVSPRTTMHFTFRLFVNNIHILFAQFCVVAKVQIKSWCL
Length654
PositionHead
OrganismTrichinella sp. T8
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Nematoda> Enoplea> Dorylaimia> Trichinellida> Trichinellidae> Trichinella> unclassified Trichinella.
Aromaticity0.10
Grand average of hydropathy-0.066
Instability index45.00
Isoelectric point7.83
Molecular weight74680.49
Publications









Function






Annotated function


GO - Cellular Component
integral component of membrane	GO:0016021	IEA:UniProtKB-KW
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP06396
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      87.98|      25|      27|     298|     324|       1
---------------------------------------------------------------------------
  298-  324 (42.67/37.86)	SGcrRFERKSTVEDTFNNWQAFPQVGS
  328-  352 (45.31/31.68)	SG..RFEFNSVGIDIQADRHLEGQVGS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     180.73|      55|     282|     232|     292|       3
---------------------------------------------------------------------------
  232-  292 (80.31/59.81)	IGSIQQAMqpDEESTYLREMAeMRKYWRLRKSKNSILGDLSLGhCTFVCLCmvSCLHLLLY
  518-  572 (100.41/53.52)	ITEMKKAL..DQLSSAQKDPV.MTVYWCYDCCRYNTIARLSLV.IPFYEYC..GSLLRILY
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      42.53|      12|     590|      37|      48|       6
---------------------------------------------------------------------------
   37-   48 (23.26/14.00)	LFVTKIH.SFLQF
  629-  641 (19.27/10.49)	LFVNNIHiLFAQF
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP06396 with Med17 domain of Kingdom Metazoa
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