<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP06392

Description Mediator of RNA polymerase II transcription subunit 24 (Fragment)
SequenceMAESSMNAVEQLLFDAWSECWPDIIFMKQLRQRIEITNQNIEQLSSLLLYYVTLSEMPNRLMLKYIRFCLDTQVVPCVAFLNVVNSYRCYEKVGCINEILVLVIYCLDKLNCDFCDADVCVRTSILVMNTVLWILAYVEYLLTSNNFPPSAHLWSLSEFCTLKSDNEARVFRNSYDNLFSANPNEILAKSVRASDSRIPSVVISLSGIFAHVQSMKGIAAMVEALKVAKDIQGESWLNILYDLIMGGILQQHDDSTTLPFSVSSSYLYLRIPRLLSQLVAEGIPKETLIGSLRRIATSEAVLNVSDTKARCNTLQAFLNVLSELGILEESEKDTLMAIRDEMRKELYVQEGQPTINLVLRAEFTLQSIVKAFDAHQALERWPQMLNTMMSGKSLLYICAAAISIDQLNLLAERLIKITETYKEVVPVGEDAQKSVPPSHDLFDMSFLLLHRLSQYYSTTTCLRPGDPFFKTWYFSSAIDLVRNMFDPEDLPQLLKNVPLDLELATDVLSRLRVGQPGWLNIRTWYCIIDLIPSIVQVVLNEVLLDTISIEELKHIFSGLLFLNIHGVSCMCSPLLCFAQYVALQKTDEATKLANSLFSFFESITPSDAERNRQTDRQTFMVNSAKKLFSTYRELPVTLMHVLRMNRAPAQLNHSPDDHFPVIGKPENIRSFFAASERAGYLTAALIARIIVLVESEQYDSWLSAFIEKVNTMQGMEKWCNLNLACCFIRPKECTLALIPLLSNYVLHDDRDLFCVAPRGNILAFFLVKLYLIALRYTTPTAVDKAETTEFSVDECSVQNNTNSSTADRSAVITSLLVRSGELCPTVAFVSNFLYCLSEYSTPEAELIKNEIPMHLIFSLLRADPDILSMRTVLRLFDLKVDMVLFANIAITVVVKLETEFTHYSRLCYSVWLLLFQFKISVTVTSRSRKKPCWPQS
Length936
PositionTail
OrganismTrichinella sp. T8
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Nematoda> Enoplea> Dorylaimia> Trichinellida> Trichinellidae> Trichinella> unclassified Trichinella.
Aromaticity0.09
Grand average of hydropathy0.172
Instability index45.23
Isoelectric point5.43
Molecular weight106311.32
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP06392
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     697.16|     232|     281|     148|     402|       1
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  148-  402 (331.40/307.94)	PPSAHLWSLSeFCTLKSdnearvFRNSYDNLFSANPNEILAKSVRASdSRIpSVVislSGIFAH...VQSMKGIAAmveALKVAKDIQ.....GE.SWLNI..LY...DLImGGILQQHDDSTTLPfSVSSSYLYLRIPRLLSqLVAEGIPkeTLIGSLRRIATSEAVLNVSDTKARCNTLQAFLNVL..SELGILEESEKDTLMAirDEMRK..ELYvQEGQPTINLVLRAEFTLQSIVKAFDAHQALERWPQMLNTMM.SGKSLLYICAAAI
  436-  686 (365.76/260.49)	PPSHDLFDMS.FLLLHR......LSQYYSTTTCLRPGDPFFKTWYFS.SAI.DLV...RNMFDPedlPQLLKNVPL...DLELATDVLsrlrvGQpGWLNIrtWYciiDLI.PSIVQVVLNEVLLD.TISIEELKHIFSGLLF.LNIHGVS..CMCSPLLCFAQYVALQKTDEATKLANSLFSFFESItpSDAERNRQTDRQTFMV..NSAKKlfSTY.RELPVTLMHVLRMNRAPAQLNHSPDDHFPVIGKPENIRSFFaASERAGYLTAALI
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      68.03|      21|      23|      81|     102|       2
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   81-  102 (33.28/26.19)	LNVVNSYRCYEKVgCI.NEILVL
  107-  128 (34.75/21.87)	LDKLNCDFCDADV.CVrTSILVM
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP06392 with Med24 domain of Kingdom Metazoa
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