<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP06391

Description Mediator of RNA polymerase II transcription subunit 24 (Fragment)
SequenceMAESSMNAVEQLLFDAWSECWPDIIFMKQLRQRIEITNQNIEQLSSLLLYYVTLSEMPNRLMLKYIRFCLDTQVVPCVAFLNVVNSYRCYEKVGCINEILVLVIYCLDKLNCDFCDADVCVRTSILVMNTVLWILAYVEYLLTSNNFPPSAHLWSLVFTLKENKFVQFCNYFVCWELSEFHDQIQVSIVNIKVKIEENRHSFPADLLDNMLTFLSFFDIENDNEARVFRNSYDNLFSANPNEILAKSVRASDSRIPSVVISLSGIFAHVQSMKGIAAMVEALKVAKDIQGESWLNILYDLIMGGILQQHDDSTTLPFSVSSSYLYLRIPRLLSQLVAEGIPKETLIGSLRRIATSEAVLNVSDTKARCNTLQAFLNVLSELGILEESEKDTLMAIRDEMRKELYVQEGQPTINLVLRAEFTLQSIVKAFDAHQALERWPQMLNTMMSGKSLLYICAAAISIDQLNLLAERLIKITETYKEVVPVGEDAQKSVPPSHDLFDMSFLLLHRLSQYYSTTTCLRPGDPFFKTWYFSSAIDLVRNMFDPEDLPQLLKNVPLDLELATDVLSRLRVGQPGWLNIRTWYCIIDLIPSIVQVVLNEVLLDTISIEELKHIFSGLLFLNIHGVSCMCSPLLCFAQYVALQKTDEATKLANSLFSFFESITPSDAERNRQTDRQTFMVNSAKKLFSTYRELPVTLMHVLRMNRAPAQLNHSPDDHFPVIGKPENIRSFFAASERAGYLTAALIARIIVLVESEQYDSWLSAFIEALQKVNTMQGMEKWCNLNLACCFIRPKECTLALIPLLSNYVLHDDRDLFCVAPRGNILAFFLVKLYLIALRYTTPTAVDKAETTEFSVDECSVQNNTNSSTADRSAVITSLRELFSCKFEVVRSGELCPTVAFVSNFLYCLSEYSTPEAELIKNEIPMHLIFSLLRADPDILSMRTVLRLFDLKVDMVLFANIAITVVVKLETEFTHYSRLCYSVWLLLFQFKISVTVTSRSRKKPCWPQS
Length1005
PositionTail
OrganismTrichinella sp. T8
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Nematoda> Enoplea> Dorylaimia> Trichinellida> Trichinellidae> Trichinella> unclassified Trichinella.
Aromaticity0.10
Grand average of hydropathy0.162
Instability index45.66
Isoelectric point5.33
Molecular weight114670.80
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP06391
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      34.29|       9|      49|     528|     538|       1
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  528-  538 (13.91/12.77)	TWYfsSAIDLV
  580-  588 (20.38/10.75)	TWY..CIIDLI
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      86.77|      33|     152|     544|     579|       2
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  483-  509 (19.46/ 6.71)	...........................PvgED.AQ..KSVPpsHDLfDMSFLLLHRL
  520-  568 (50.03/31.79)	RPGDPFF...KtwyfssaidlvrnmfdP..EDLPQLLKNVP..LDL.ELATDVLSRL
  569-  602 (17.28/14.05)	RVGQPGWlniR.......twyciidliP..SIVQVVLNEVL..LD............
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     211.14|      68|     281|      15|      89|       3
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   15-   89 (111.63/83.60)	DAWSECWPDIIFMKQLRQRIEITNQNIEQLSSLLlyYVT....LSEM.....PNRLMLKYIRfcldtQVVPCVAFLNVVNS.YRC
  291-  368 (99.51/58.60)	ESWLNILYDLIMGGILQQHDDSTTLPFSVSSSYL..YLRiprlLSQLvaegiPKETLIGSLR.....RIATSEAVLNVSDTkARC
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     106.32|      35|     281|     410|     459|       4
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  370-  408 (50.29/50.52)	TLQAFLNVLSELGILEESEK..DTLMAirdeMRKELYVQEG
  421-  457 (56.03/44.84)	TLQSIVKAFDAHQALERWPQmlNTMMS....GKSLLYICAA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      68.37|      24|      53|     100|     124|       5
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  100-  124 (41.48/29.51)	LVL...........................VIYCLdKLN..CDFCDADVCVRTS
  126-  178 (26.90/13.37)	LVMntvlwilayveylltsnnfppsahlwsLVFTL.KENkfVQFCNYFVCWELS
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     286.00|      95|     479|     185|     290|       9
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  185-  290 (137.41/121.13)	QVSIVNIKVKIEENRHSFPADLLdNMLTFlsffdieNDNEARvFRNSYDNLFS..ANPNEIlaKSVRASDSRIPSVVISL.SGIFAHVQSMK...GIAAMVEALKVAKDIQG
  674-  774 (148.59/100.13)	QTFMVNSAKKLFSTYRELPVTLM.HVLRM.......NRAPAQ.LNHSPDDHFPviGKPENI..RSFFAASERAGYLTAALiARIIVLVESEQydsWLSAFIEALQKVNTMQG
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP06391 with Med24 domain of Kingdom Metazoa
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