<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP06389

Description Mediator of RNA polymerase II transcription subunit 24
SequenceMAESSMNAVEQLLFDAWSECWPDIIFMKQLRQRIEITNQNIEQLSSLLLYYVTLSEMPNRLMLKYIRFCLDTQVVPCVAFLNVVNSYRCYEKVGCINEILVLVIYCLDKLNCDFCDADVCVRTSILVMNTVLWILAYVEYLLTSNNFPPSAHLWSLVFTLKENKFVQFCNYFVCWELSEFHDQIQVSIVNIKVKIEENRHSFPADLLDNMLTFLSFFDIENDNEARVFRNSYDNLFSANPNEILAKSVRASDSRIPSVVISLSGIFAHVQSMKGIAAMVEALKVAKDIQGESWLNILYDLIMGGILQQHDDSTTLPFSVSSSYLYLRIPRLLSQLVAEGIPKETLIGSLRRIATSEAVLNVSDTKARCNTLQAFLNVLSELGILEESEKDTLMAIRDEMRKELYVQEGQPTINLVLRAEFTLQSIVKAFDAHQALERWPQMLNTMMSGKSLLYICAAAISIDQLNLLAERLIKITETYKEVVPVGEDAQKSVPPSHDLFDMSFLLLHRLSQYYSTTTCLRPGDPFFKTWYFSSAIDLVRNMFDPEDLPQLLKNVPLDLELATDVLSRLRVGQPGWLNIRTWYCIIDLIPSIVQVVLNEVLLDTISIEELKHIFSGLLFLNIHGVSCMCSPLLCFAQYVALQKTDEATKLANSLFSFFESITPSDAERNRQTDRQTFMVNSAKKLFSTYRELPVTLMHVLRMNRAPAQLNHSPDDHFPVIGKPENIRSFFAASERAGYLTAALIARIIVLVESEQYDSWLSAFIEALQKVNTMQGMEKWCNLNLACCFIRPKECTLALIPLLSNYVLHDDRDLFCVAPRGNILAFFLVKLYLIALRYTTPTAVDKAETTEFSVGNGQLEI
Length859
PositionTail
OrganismTrichinella sp. T8
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Nematoda> Enoplea> Dorylaimia> Trichinellida> Trichinellidae> Trichinella> unclassified Trichinella.
Aromaticity0.10
Grand average of hydropathy0.149
Instability index45.67
Isoelectric point5.17
Molecular weight97886.40
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP06389
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      34.29|       9|      49|     528|     538|       1
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  528-  538 (13.91/13.49)	TWYfsSAIDLV
  580-  588 (20.38/11.41)	TWY..CIIDLI
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      86.77|      33|     152|     544|     579|       2
---------------------------------------------------------------------------
  483-  509 (19.46/ 7.78)	...........................PvgED.AQ..KSVPpsHDLfDMSFLLLHRL
  520-  568 (50.03/36.07)	RPGDPFF...KtwyfssaidlvrnmfdP..EDLPQLLKNVP..LDL.ELATDVLSRL
  569-  602 (17.28/16.06)	RVGQPGWlniR.......twyciidliP..SIVQVVLNEVL..LD............
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     210.90|      68|     281|      15|      89|       3
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   15-   89 (110.77/84.00)	DAWSECWPDIIFMKQLRQRIEITNQNIEQLSSLLlyYVT....LSEM.....PNRLMLKYIRfcldtQVVPCVAFLNVVNS.YRC
  291-  368 (100.14/60.16)	ESWLNILYDLIMGGILQQHDDSTTLPFSVSSSYL..YLRiprlLSQLvaegiPKETLIGSLR.....RIATSEAVLNVSDTkARC
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     106.32|      35|     281|     410|     459|       4
---------------------------------------------------------------------------
  370-  408 (50.29/46.11)	TLQAFLNVLSELGILEESEK..DTLMAirdeMRKELYVQEG
  421-  457 (56.03/40.93)	TLQSIVKAFDAHQALERWPQmlNTMMS....GKSLLYICAA
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     268.74|      96|     479|     185|     290|       7
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  193-  290 (155.88/122.38)	VKIEENRHSFPADLL..........DNMLTFLSFFDIENDNEARVFRNSYDNLFS..ANPNEIlaKSVRASDSRIPSVVISL.SGIFAHVQSMK...GIAAMVEALKVAKDIQG
  604-  657 (40.74/16.26)	ISIEELKHIFSGLLFlnihgvscmcSPLLCFAQYVALQKTDEATKLANSLFSFF............................................................
  708-  774 (72.12/42.89)	.............................................LNHSPDDHFPviGKPENI..RSFFAASERAGYLTAALiARIIVLVESEQydsWLSAFIEALQKVNTMQG
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP06389 with Med24 domain of Kingdom Metazoa
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