<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP06388

Description Mediator of RNA polymerase II transcription subunit 24 (Fragment)
SequenceMAESSMNAVEQLLFDAWSECWPDIIFMKQLRQRIEITNQNIEQLSSLLLYYVTLSEMPNRLMLKYIRFCLDTQVVPCVAFLNVVNSYRCYEKVGCINEILVLVIYCLDKLNCDFCDADVCVRTSILVMNTVLWILAYVEYLLTSNNFPPSAHLWSLVFTLKENKFVQFCNYFVCWELSEFHDQIQVSIVNIKVKIEENRHSFPADLLDNMLTFLSFFDIENDNEARVFRNSYDNLFSANPNEILAKSVRASDSRIPSVVISLSGIFAHVQSMKGIAAMVEALKVAKDIQGESWLNILYDLIMGGILQQHDDSTTLPFSVSSSYLYLRIPRLLSQLVAEGIPKETLIGSLRRIATSEAVLNVSDTKARCNTLQAFLNVLSELGILEESEKDTLMAIRDEMRKELYVQEGQPTINLVLRAEFTLQSIVKAFDAHQALERWPQMLNTMMSGKSLLYICAAAISIDQLNLLAERLIKITETYKEVVPVGEDAQKSVPPSHDLFDMSFLLLHRLSQYYSTTTCLRPGDPFFKTWYFSSAIDLVRNMFDPEDLPQLLKNVPLDLELATDVLSRLRVGQPGWLNIRTWYCIIDLIPSIVQVVLNEVLLDTISIEELKHIFSGLLFLNIHGVSCMCSPLLCFAQYVALQKTDEATKLANSLFSFFESITPSDAERNRQTDRQTFMVNSAKKLFSTYRELPVTLMHVLRMNRAPAQLNHSPDDHFPVIGKPENIRSFFAASERAGYLTAALIARIIVLVESEQYDSWLSAFIEALQKVNTMQGMEKWCNLNLACCFIRPKECTLALIPLLSNYVLHDDRDLFCVAPRGNILAFFLVKLYLIALRYTTPTAVDKAETTEFSVGELFSCKFEVVRSGELCPTVAFVSNFLYCLSEYSTPEAELIKNEIPMHLIFSLLRADPDILSMRTVLRLFDLKVDMVLFANIAITVVVKLETEFTHYSRLCYSVWLLLFQFKISVTVTSRSRKKPCWPQS
Length982
PositionTail
OrganismTrichinella sp. T8
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Nematoda> Enoplea> Dorylaimia> Trichinellida> Trichinellidae> Trichinella> unclassified Trichinella.
Aromaticity0.10
Grand average of hydropathy0.183
Instability index45.60
Isoelectric point5.36
Molecular weight112177.18
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP06388
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      34.29|       9|      49|     528|     538|       1
---------------------------------------------------------------------------
  528-  538 (13.91/12.95)	TWYfsSAIDLV
  580-  588 (20.38/10.94)	TWY..CIIDLI
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      58.93|      22|     152|     544|     579|       2
---------------------------------------------------------------------------
  520-  557 (33.25/23.52)	RPGDPFF...KtwyfssaidlvrnmfdPEDLPQLLKNVPLD
  569-  602 (25.68/10.43)	RVGQPGWlniR.......twyciidliPSIVQVVLNEVLLD
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      55.19|      22|      52|     100|     124|       4
---------------------------------------------------------------------------
   68-  102 (19.37/12.32)	FCLDTqvVPCvAFlnvvnsyrCYEKVgCI.NEiLVL
  105-  128 (35.82/25.94)	YCLDK..LNC.DF........CDADV.CVrTSiLVM
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      53.97|      17|     281|     196|     214|       5
---------------------------------------------------------------------------
  196-  214 (26.58/26.87)	EENRHSFPA..DLLDnmLTFL
  486-  504 (27.39/18.74)	EDAQKSVPPshDLFD..MSFL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     106.32|      35|     281|     410|     459|       6
---------------------------------------------------------------------------
  370-  408 (50.29/42.98)	TLQAFLNVLSELGILEESEK..DTLMAirdeMRKELYVQEG
  421-  457 (56.03/38.13)	TLQSIVKAFDAHQALERWPQmlNTMMS....GKSLLYICAA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      61.21|      18|     479|     279|     296|      12
---------------------------------------------------------------------------
  279-  296 (31.42/22.07)	VEALKVAKDIQG.ESWLNI
  763-  781 (29.79/20.54)	IEALQKVNTMQGmEKWCNL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      43.30|      13|      19|     132|     147|      14
---------------------------------------------------------------------------
  132-  147 (19.17/19.21)	LWILAYVeylLTSNNF
  153-  165 (24.13/13.93)	LWSLVFT...LKENKF
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP06388 with Med24 domain of Kingdom Metazoa
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