<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP06382

Description "Serine--tRNA ligase, cytoplasmic"
SequenceMSVSLSDFEAKVKNLFKEHAKSGIAHFFFRPYLITSSEECEKEIVISTANELMEIFTSLPQNLQESAFSIVISHRVLSNSANKIVDFFVRNVIQRQMLSIKCICEKLLTCAELNINSCGWNDTFAFFMENISLLDYKDLLNPQMRLLTHVFMHYTYRDAIAVLLGTAKPEKSRIPYFEEVITEIILELMFTAECDHSQLNPQAWRIISTQIIYLTLQQSICFTRLVKILHTKLTHYPYRYARNQLMWCLFNFLSGGMQKYSGKSAWPSPALVETYCRMLTYPDLEILGLKQFTSHIVLTAARHQCCEMMYICCEILNYRLFNIPSTYRVHAIVTLQQTLAFAKFQTNASLYWMYRYYYYYYYYYFAPFARLLNSFVAVAADGTKQSIAENEELMRIIILTLARSTVISSKVLGPRKVLVHLKSLADFLVYETNSADVNRCVDVLNRLIFKYAVVPLERFMLTMLLRDYEGNDAFYALLIVMLLVQRSEELRSAVADCVAMLPSDYWHCQDWNDKYQAYQIKHAERTWSQVYVELSRASLTPNDCPLPVYFGTRCLQMLPVVDLLLQKLVESPAACLKFLDSTLSILGPLYRFHPYPVSFLYSTFRFYEKRLVESPAIKQKLALAVHGACVPSRDDHWLLSAEFVGWVGQATDRGPWVPDLNYYGALVRRLIDTFSEPRQQWSRKTDLRFVEFNNFQTHALYSICIELMSLPVGVVDVGNALVTLVTHWHSLVDKNTVMYWVNAIGLIFSALPISYMEPFYQTILTTLCSDNMNSINTDVSNKLDFEKRSKLMEDCYPARILALCHAVWLHSTSGYLQLLPQALRSTWIPHVRSEGQFLYVCHLVAPFLQRFYQERTKFTMDITTDLYQMLYNVDCEVGNWKYEDLICDFFYHVKYMYVGDSVRQDTDRIIPMLRPSLQQKLRYISFAQGEQSAGTPFSEMINPIKLLGIQMVVWLQRLPIFGETAQHFWLAVTKLGDPLCFHFLAPLRWIWILLDDRPYWWVHTAGVSGQLSHPLKQFQWTCETGPGSPSGHAMVSASVWFNLLYNLQSDLVLGDLCGICWLLYVVFLIAVSISRTYISAHFPDQVILGIVVGICIALVTRSLVGHRRRRWSNLIAFMIALLLIALSVHEVHRFFGVDTHRSIELAAKYCHRAEWIHQSTTPLASFFRDVGVLISVAILLANKSMFTNNNKIASKFFSTKFAQALLGVGLNQLVAFIPIGRLPTALFYAVLLPALIVLLLTMVLDLDNFRVEKGGNVQAVRVSQQKRFQSVDLVDQVVETDQEWRRSRYLSDEWNRLKNLCSKEIGEKIKRKEPVDGNSTLPDSLTDKLQKLTVDQIRALSVGQIKQLRLLIDHEMEKSYKLVENLEAVRFKALSQIGNLVHNSVPVSENEDDNEIVRTWGELEVRKKYSQVDLGIMVDGYDSERGCSVAGSRGYFLKGPLVFLEQALIQLAMHMLFKKKYTPLYTPFFMRKEVMQEVAQLSDFDDQLYKVIGKSSEVKEEIAEEEKYLIATSEQPIAAYHRDEWISKESLPLRYVGFSTCFRQEVGSHGRDTSGIFRVHQFEKVEQFCITSPHDDASWEMLEEMISNAEMFYQTLNIPYRVVSIVSGELNNAAAKKYDLEAWFPGSGAFRELVSCSNCTDYQSRRLRIRYGQTKKMMAKAEFVHMLNGTMCATTRTICAILENFQEENGIAVPEALRQYMPDDYKDFIPFVKPAPKVEQAAKRGNKSATAEKSTQ
Length1736
PositionTail
OrganismTrichinella sp. T8
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Nematoda> Enoplea> Dorylaimia> Trichinellida> Trichinellidae> Trichinella> unclassified Trichinella.
Aromaticity0.12
Grand average of hydropathy0.002
Instability index40.44
Isoelectric point7.36
Molecular weight199931.36
Publications









Function






Annotated function


GO - Cellular Component
integral component of membrane	GO:0016021	IEA:UniProtKB-KW
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
ATP binding	GO:0005524	IEA:UniProtKB-KW
serine-tRNA ligase activity	GO:0004828	IEA:UniProtKB-EC

GO - Biological Process
seryl-tRNA aminoacylation	GO:0006434	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP06382
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     155.41|      47|      81|     454|     503|       1
---------------------------------------------------------------------------
  454-  503 (77.00/55.15)	VPLERFMLT...MLLRDYEGNDAFYALLIVMLLVQRseeLRSAVADCVAMLPS
  532-  581 (78.41/48.91)	VELSRASLTpndCPLPVYFGTRCLQMLPVVDLLLQK...LVESPAACLKFLDS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      68.58|      20|      20|    1092|    1111|       2
---------------------------------------------------------------------------
 1092- 1111 (35.84/24.46)	VGICIALVTRSLVGHRRRRW
 1115- 1134 (32.74/21.69)	IAFMIALLLIALSVHEVHRF
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     175.55|      53|      81|     103|     159|       3
---------------------------------------------------------------------------
  103-  159 (91.14/58.02)	ICEKLLT..CAELNINSCGWNdtfaFFMENISLLDYKDL..LNPQMRLLTHVFMHYTYRDA
  185-  241 (84.41/45.66)	ILELMFTaeCDHSQLNPQAWR....IISTQIIYLTLQQSicFTRLVKILHTKLTHYPYRYA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     113.79|      31|      82|     828|     858|       5
---------------------------------------------------------------------------
  801-  834 (30.94/14.68)	...LA...LCHAVwlhstSGYL...QLLPQAlRSTWIPHVR.SE
  835-  865 (52.32/29.88)	GQFLY...VCHLV.....APFL...QRFYQE.RTKFTMDIT.TD
  878-  917 (30.54/14.40)	GNWKYedlICDFF...yhVKYMyvgDSVRQD.TDRIIPMLRpSL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     112.07|      25|      82|     656|     680|       6
---------------------------------------------------------------------------
  626-  638 (17.95/ 7.00)	.....HG.......ACV.......PSRDDHWL
  639-  657 (30.88/18.24)	LSAEFVG.......WVGQ......ATDRGPWV
  658-  682 (43.93/29.59)	PDLNYYG.......ALVRRLIDTFSEPRQQWS
  685-  711 (19.31/ 8.18)	TDLRFVEfnnfqthALYSICIELMSLP.....
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     115.86|      34|     258|     714|     794|       7
---------------------------------------------------------------------------
  753-  786 (61.86/91.76)	ISYMEPFYQT..ILTTLCSDNMNSINTDVSNKLDFE
 1586- 1621 (54.00/10.82)	ISNAEMFYQTlnIPYRVVSIVSGELNNAAAKKYDLE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     101.63|      28|      29|     961|     989|       9
---------------------------------------------------------------------------
  961-  989 (47.99/34.03)	FGETAQHFWLAVTKLGDPLCfHFLAPLRW
  993- 1020 (53.65/33.19)	LLDDRPYWWVHTAGVSGQLS.HPLKQFQW
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     118.23|      35|      83|     307|     347|      10
---------------------------------------------------------------------------
  276-  310 (63.90/46.82)	CRMLTYPDLEILGLKQFTSHIVLTA....ARHQCCEMMY
  313-  351 (54.32/41.61)	CEILNYRLFNIPSTYRVHAIVTLQQtlafAKFQTNASLY
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      57.56|      17|      26|    1464|    1480|      15
---------------------------------------------------------------------------
 1464- 1480 (30.62/26.91)	LYTPFFMRKEVMQEVAQ
 1488- 1504 (26.93/22.51)	LYKVIGKSSEVKEEIAE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      61.50|      20|      29|      49|      70|      16
---------------------------------------------------------------------------
   49-   70 (28.11/25.74)	ANELMEIFTSlpQNLQESAFSI
   81-  100 (33.39/22.40)	ANKIVDFFVR..NVIQRQMLSI
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP06382 with Med23 domain of Kingdom Metazoa
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