<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP06372

Description Coiled-coil domain-containing protein 47
SequenceMMELRDVLYATPYRPKSSAAHVFESIKPRPILNITPECSEDEDCNSGTSGKDSDKMLKREIADSSPNSCSRGKQLNKPFLNTCEALIEKIKRVKKIDPSTLAKEQIRRNEHYYQKIAMKKILLVLYLDKKMQEIDKNFINSVGSIVQNIKSIQSSISEVLAKLQMVDQPSLLNSFRVISSQFNSVLQLLRSDRASHFKNYVFLPIRLSVEVDADLEAATENRLHAWTHAVVPDYLRTKPDPQVEQKDQQISNQVQQRLCNPESLLKQVTAFNRCLNCILDSLNASIRDSEMDGRKTSKTSDSEDTALLVAAILKGQNVKPAYSATPTSSRGSSGDSGRKVCIWMFFLSCLFELVELSVKQVSQIDDNEFAEFEEFDVELDASVDADFMANNVNERETPPVDTASIGAKRSPANAEQKRNDAPNNNFNDDDYGIVEDESVDDFSHLLDENEFENFPDERKPGKQNAGPSKPVTQLKITDVPGHLRNNWNNFVVELFLIFGLIVYVMNYIYGKTKNHSLAVAWFDSNRPFLEENFSIVGDDGISPEVTKNVLIKESDNHYIVWCSGRQGCIGMEIHLKLIKRQDLLSLIFYIIRPKFDIIEIKIILNPEEMDPFVFALGTKRSAIKNAKEIMDLNLYCSEKKNVEKLGLPSSYVLHSEIGEVTTGLLDSKMVSALCKYKDVVDYIHISDQFVGIKPIEMENMAKPPETAKVVMICLNIPGQLRATEEDVCTLQPLMIFIFHVLEKVRRFRLTREGKQKADKNRQYVEESFLKTTHAQRQEAAQQRREERARERKERLMAEEDPERQRKLEKQELKRELKKKQPRVKQIKIKAM
Length831
PositionHead
OrganismTrichinella papuae
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Nematoda> Enoplea> Dorylaimia> Trichinellida> Trichinellidae> Trichinella.
Aromaticity0.07
Grand average of hydropathy-0.496
Instability index46.36
Isoelectric point6.36
Molecular weight95005.54
Publications









Function






Annotated function


GO - Cellular Component
integral component of membrane	GO:0016021	IEA:UniProtKB-KW
mediator complex	GO:0016592	IEA:InterPro
rough endoplasmic reticulum membrane	GO:0030867	IEA:UniProtKB-SubCell

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP06372
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      66.60|      24|      25|     144|     168|       1
---------------------------------------------------------------------------
  130-  160 (31.64/22.26)	KMQEIDKnfinsvgSIVQNIKSIQSSISEVL
  162-  186 (34.96/19.93)	KLQMVDQ......pSLLNSFRVISSQFNSVL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      59.12|      17|      30|      29|      45|       3
---------------------------------------------------------------------------
   29-   45 (32.75/18.06)	RPILNITPE.CSEDEDCN
   59-   76 (26.37/13.32)	REIADSSPNsCSRGKQLN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      76.58|      24|      25|     754|     777|       5
---------------------------------------------------------------------------
  754-  777 (38.18/25.93)	KQKADKNRQYVEESFLKTTHAQRQ
  781-  804 (38.40/26.12)	QQRREERARERKERLMAEEDPERQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     112.02|      36|     235|     469|     506|       7
---------------------------------------------------------------------------
  469-  506 (59.73/51.21)	KPVTQLKIT....DVPGHLRNNWNNF.VVELFLIFglIVYVMN
  702-  742 (52.28/37.44)	KPPETAKVVmiclNIPGQLRATEEDVcTLQPLMIF..IFHVLE
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP06372 with Med8 domain of Kingdom Metazoa
Unable to open file!