<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP06369

Description Putative delta-1-pyrroline-5-carboxylate synthase
SequenceMNSGNAEDEEDQNLLVAVESLREWKVYDISFTGVERYLQPLHYNDHVAELAHNVRWSRLVGNSSRCLSNIGRTERVDDPSSGRAAWDNVARSLHSALTEMVVLMDLIKVTLTGRYMTFDEALHDISSDDGKPVFRSGEAYALFAKRKALSITSNVLLDFVGKQKQKVSGIGSIQQAMQPDEESTYLREMAEMRKFWRLKKSKNSIIGDLSYGHCLPKFPPQSTFEICRKENWSNAGKHPSIETSTLKILLPDDLKDDRRLRVHLMTGKHFLKLIPYMRLCVSSATSLELTSKPVVTWQDRLQVAQSSMFFRDLYLTICKETMVFDDNTSFMYRDFLILRLDNNHALVISLFSTAELEEARKNIPNDKRTKRLLAETKLQCVFALQQRMCGRYMHKVDTLCNFISNKPVTAPLIVQTHPAPFAGVEMKSQQQIEHLEKCQPSFLLLNILEDARHYILITEMKKALDQLSSAQKDPVMTVYWCYDCCRYNTIARLSLVIPFYEYCGRFTIMIEASLNRIVITSKDCSTVKMVGCVDELITYVKMKCRQYLISTIGVVIRPLDWQTINSSMCTLDSNGCMMPTITIVSPCATKLLRILYPLNSDQVQIFLLKIDGENPSWDNWYNCLPDAYVPIDLNNLAGTSMLHRIETLITLMGEKNNTQLQMCGTAENSEAKPQRKFAQNFKYSLKRFSNKIDKRWLTSAGCAMLMVQLVIALILAASLIIPHCYNVAQELKTVDFNNDENDALDDDDINALFVKKVCNWPLTCPEFSGQIFAATAVVASMIGNILLAFILIFKIDRFFQISSDRLGESSIFIPCSSLHTWNNVDEIIIYHGMAGLAYLIAGTIMSWYAYDEKHFHNAEDRFYTQWIVATNSAPRNQTGIFVIRRRRILISVLREKLGRIQGKSFKPTFKMLTRTMCSLGFFKIVRTIARRQYFSDANYTIKAPKFKSIILHRGDINKAKRVVIKLGSAIVARDNEDGLALGRLASIASELQLSGRQVLIVTSGAVAFGRQKMRHERLLSMSLRQTLLPNSFGSETTIDKRVCAASGMLGLMTVYEQLFAQYGISTAQVLLTKPDIESDERRRVLVSTIESLLSLKVVPILNGNDAVAPEQKDGLGDNDTLASKISAAIAADLLITLSNVDGLYTGPPGQEGSRLLTHFSPCSKSSLIFGDGSKLGTGGMESKISWARWALDQGVVSVICNGKSENVIRNVMSGRKIGTLITAVEPEEIPVEEQAIKAREALQILSTLSNDIRAEIVIKLAELLKAKEMDIIAANQVDIDKATRAGLENVKIARLKLTRDKLHSLYEGLLQISNSAKTTLGKSLRKIKIGEDLHLEQVTIPIGLLLVIFESRPDCLPQISSLAIASGNALLLKGGQEASNSNSYLLEIVQEALISVSPSLKDAVNKREDIEDLLQLNQYIDLVIPRGSSALVKKIQQQSQSIPVLGHSEGICHVYLDKDCDHEKAIKIVINSKCDYPAACNAAETILVHRSLLKNGQFFDNLCHQLTEHGVTIFSGPKLAESLQFSPPLAKSMKHEYGSLQCTLEVVEDVEGAEKHILKFGSSHTDCIVTENSETAEHFVQHVDSACVFVNASTRFADGYRFGLGAEVGISTGRIHARGPVGIDGLLTTKWILRGNGHTLDDFAAGGRYTYIHQVLS
Length1657
PositionHead
OrganismTrichinella papuae
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Nematoda> Enoplea> Dorylaimia> Trichinellida> Trichinellidae> Trichinella.
Aromaticity0.07
Grand average of hydropathy-0.078
Instability index36.84
Isoelectric point8.12
Molecular weight185235.81
Publications









Function






Annotated function


GO - Cellular Component
integral component of membrane	GO:0016021	IEA:UniProtKB-KW

GO - Biological Function
ATP binding	GO:0005524	IEA:UniProtKB-KW
glutamate 5-kinase activity	GO:0004349	IEA:UniProtKB-EC
glutamate-5-semialdehyde dehydrogenase activity	GO:0004350	IEA:UniProtKB-EC

GO - Biological Process
L-proline biosynthetic process	GO:0055129	IEA:UniProtKB-UniPathway









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP06369
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     236.70|      84|     276|     983|    1075|       1
---------------------------------------------------------------------------
  983- 1075 (129.28/118.47)	RLASI..ASELQ.LSGRQVLI...VTSG..AVAFGRQKMRHERLlsMSLRQTLLPNSFGSETTIDKRvcaasgmLGLMTVYEQL.FAQYGISTAQVLL...TKPD
 1259- 1354 (107.42/77.81)	KLAELlkAKEMDiIAANQVDIdkaTRAGleNVKIARLKLTRDKL..HSLYEGLLQISNSAKTTLGKS.......LRKIKIGEDLhLEQVTIPIGLLLVifeSRPD
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     228.18|      55|     340|     446|     502|       3
---------------------------------------------------------------------------
  446-  502 (88.72/56.10)	NILEDARHYILITEMKKALDQLSSAQ..................KDPVMTvYWCYDCCRYnTIARLSLVIPFYEY
  510-  556 (65.94/34.36)	..IEASLNRIVITSKDCSTVKMVGC...................VDELIT.YVKMKCRQY.LISTIGVVI.....
  784-  850 (73.52/39.07)	NIL...LAFILIFKIDRFF.QISSDRlgessifipcsslhtwnnVDEIII.YHGMAGLAY.LIA..GTIMSWYAY
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      91.51|      30|     342|     233|     265|       4
---------------------------------------------------------------------------
  233-  265 (43.43/37.96)	SNAGKHPSI......ETSTLKILLPddLKDDrRLRVHLM
  573-  608 (48.08/29.85)	SNGCMMPTItivspcATKLLRILYP..LNSD.QVQIFLL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     315.43|     101|     118|    1371|    1479|      14
---------------------------------------------------------------------------
 1371- 1479 (142.86/132.92)	LLKGGQEASNSNSYLLEivQEALISVSPSLKDAVNKREDIEDLLQlNQYIDLvipRGSSALVKKIQQQSQSIPVLGHSEGIChVYLDKDCDHEKAIKIViNSKCDYPAA
 1492- 1592 (172.57/126.61)	LLKNGQFFDNLCHQLTE..HGVTIFSGPKLAESLQFSPPLAKSMK.HEYGSL...QCTLEVVEDVEGAEKHILKFGSSHTDC.IVTENSETAEHFVQHV.DSACVFVNA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      72.80|      23|    1068|       7|      29|      15
---------------------------------------------------------------------------
    7-   29 (40.03/24.99)	EDEEDQNLLVA.VESLREWKVYDI
 1077- 1100 (32.77/19.19)	ESDERRRVLVStIESLLSLKVVPI
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP06369 with Med17 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




NANANA









Molecular Recognition Features






MoRF SequenceStartStop




NANANA