<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP06369

Description Putative delta-1-pyrroline-5-carboxylate synthase
SequenceMNSGNAEDEEDQNLLVAVESLREWKVYDISFTGVERYLQPLHYNDHVAELAHNVRWSRLVGNSSRCLSNIGRTERVDDPSSGRAAWDNVARSLHSALTEMVVLMDLIKVTLTGRYMTFDEALHDISSDDGKPVFRSGEAYALFAKRKALSITSNVLLDFVGKQKQKVSGIGSIQQAMQPDEESTYLREMAEMRKFWRLKKSKNSIIGDLSYGHCLPKFPPQSTFEICRKENWSNAGKHPSIETSTLKILLPDDLKDDRRLRVHLMTGKHFLKLIPYMRLCVSSATSLELTSKPVVTWQDRLQVAQSSMFFRDLYLTICKETMVFDDNTSFMYRDFLILRLDNNHALVISLFSTAELEEARKNIPNDKRTKRLLAETKLQCVFALQQRMCGRYMHKVDTLCNFISNKPVTAPLIVQTHPAPFAGVEMKSQQQIEHLEKCQPSFLLLNILEDARHYILITEMKKALDQLSSAQKDPVMTVYWCYDCCRYNTIARLSLVIPFYEYCGRFTIMIEASLNRIVITSKDCSTVKMVGCVDELITYVKMKCRQYLISTIGVVIRPLDWQTINSSMCTLDSNGCMMPTITIVSPCATKLLRILYPLNSDQVQIFLLKIDGENPSWDNWYNCLPDAYVPIDLNNLAGTSMLHRIETLITLMGEKNNTQLQMCGTAENSEAKPQRKFAQNFKYSLKRFSNKIDKRWLTSAGCAMLMVQLVIALILAASLIIPHCYNVAQELKTVDFNNDENDALDDDDINALFVKKVCNWPLTCPEFSGQIFAATAVVASMIGNILLAFILIFKIDRFFQISSDRLGESSIFIPCSSLHTWNNVDEIIIYHGMAGLAYLIAGTIMSWYAYDEKHFHNAEDRFYTQWIVATNSAPRNQTGIFVIRRRRILISVLREKLGRIQGKSFKPTFKMLTRTMCSLGFFKIVRTIARRQYFSDANYTIKAPKFKSIILHRGDINKAKRVVIKLGSAIVARDNEDGLALGRLASIASELQLSGRQVLIVTSGAVAFGRQKMRHERLLSMSLRQTLLPNSFGSETTIDKRVCAASGMLGLMTVYEQLFAQYGISTAQVLLTKPDIESDERRRVLVSTIESLLSLKVVPILNGNDAVAPEQKDGLGDNDTLASKISAAIAADLLITLSNVDGLYTGPPGQEGSRLLTHFSPCSKSSLIFGDGSKLGTGGMESKISWARWALDQGVVSVICNGKSENVIRNVMSGRKIGTLITAVEPEEIPVEEQAIKAREALQILSTLSNDIRAEIVIKLAELLKAKEMDIIAANQVDIDKATRAGLENVKIARLKLTRDKLHSLYEGLLQISNSAKTTLGKSLRKIKIGEDLHLEQVTIPIGLLLVIFESRPDCLPQISSLAIASGNALLLKGGQEASNSNSYLLEIVQEALISVSPSLKDAVNKREDIEDLLQLNQYIDLVIPRGSSALVKKIQQQSQSIPVLGHSEGICHVYLDKDCDHEKAIKIVINSKCDYPAACNAAETILVHRSLLKNGQFFDNLCHQLTEHGVTIFSGPKLAESLQFSPPLAKSMKHEYGSLQCTLEVVEDVEGAEKHILKFGSSHTDCIVTENSETAEHFVQHVDSACVFVNASTRFADGYRFGLGAEVGISTGRIHARGPVGIDGLLTTKWILRGNGHTLDDFAAGGRYTYIHQVLS
Length1657
PositionHead
OrganismTrichinella papuae
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Nematoda> Enoplea> Dorylaimia> Trichinellida> Trichinellidae> Trichinella.
Aromaticity0.07
Grand average of hydropathy-0.078
Instability index36.84
Isoelectric point8.12
Molecular weight185235.81
Publications









Function






Annotated function


GO - Cellular Component
integral component of membrane	GO:0016021	IEA:UniProtKB-KW

GO - Biological Function
ATP binding	GO:0005524	IEA:UniProtKB-KW
glutamate 5-kinase activity	GO:0004349	IEA:UniProtKB-EC
glutamate-5-semialdehyde dehydrogenase activity	GO:0004350	IEA:UniProtKB-EC

GO - Biological Process
L-proline biosynthetic process	GO:0055129	IEA:UniProtKB-UniPathway









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP06369
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     236.70|      84|     276|     983|    1075|       1
---------------------------------------------------------------------------
  983- 1075 (129.28/118.47)	RLASI..ASELQ.LSGRQVLI...VTSG..AVAFGRQKMRHERLlsMSLRQTLLPNSFGSETTIDKRvcaasgmLGLMTVYEQL.FAQYGISTAQVLL...TKPD
 1259- 1354 (107.42/77.81)	KLAELlkAKEMDiIAANQVDIdkaTRAGleNVKIARLKLTRDKL..HSLYEGLLQISNSAKTTLGKS.......LRKIKIGEDLhLEQVTIPIGLLLVifeSRPD
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     228.18|      55|     340|     446|     502|       3
---------------------------------------------------------------------------
  446-  502 (88.72/56.10)	NILEDARHYILITEMKKALDQLSSAQ..................KDPVMTvYWCYDCCRYnTIARLSLVIPFYEY
  510-  556 (65.94/34.36)	..IEASLNRIVITSKDCSTVKMVGC...................VDELIT.YVKMKCRQY.LISTIGVVI.....
  784-  850 (73.52/39.07)	NIL...LAFILIFKIDRFF.QISSDRlgessifipcsslhtwnnVDEIII.YHGMAGLAY.LIA..GTIMSWYAY
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      91.51|      30|     342|     233|     265|       4
---------------------------------------------------------------------------
  233-  265 (43.43/37.96)	SNAGKHPSI......ETSTLKILLPddLKDDrRLRVHLM
  573-  608 (48.08/29.85)	SNGCMMPTItivspcATKLLRILYP..LNSD.QVQIFLL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     315.43|     101|     118|    1371|    1479|      14
---------------------------------------------------------------------------
 1371- 1479 (142.86/132.92)	LLKGGQEASNSNSYLLEivQEALISVSPSLKDAVNKREDIEDLLQlNQYIDLvipRGSSALVKKIQQQSQSIPVLGHSEGIChVYLDKDCDHEKAIKIViNSKCDYPAA
 1492- 1592 (172.57/126.61)	LLKNGQFFDNLCHQLTE..HGVTIFSGPKLAESLQFSPPLAKSMK.HEYGSL...QCTLEVVEDVEGAEKHILKFGSSHTDC.IVTENSETAEHFVQHV.DSACVFVNA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      72.80|      23|    1068|       7|      29|      15
---------------------------------------------------------------------------
    7-   29 (40.03/24.99)	EDEEDQNLLVA.VESLREWKVYDI
 1077- 1100 (32.77/19.19)	ESDERRRVLVStIESLLSLKVVPI
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP06369 with Med17 domain of Kingdom Metazoa
Unable to open file!