<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP06366

Description Endoplasmic reticulum-Golgi intermediate compartment protein 3
SequenceMLNNIESEEEQRIRFQVELEFVQCLANPNYLNYLAQRDFFKNPAFINYLKYLLYWKRQEYAKYLKFPQCLYILELLQTEEFRTAMMRVPNSKFLEDQMLLQWQFYIRKRDSVRLPSRCETCKYLALELEARFSETGQSPETTFNGRGGTKKYRDSELRFIETMENLCDRLLEYNLHKEHKNSLRFARGQSETMKTLHGLVNRGVQVELGLPYELWDSPSVEITRMKQDCETILENNEEAIERWYYAKQKEPLRHYLCENRSFLHIILHTVVINFRMLSQVIRQMRRLDAYSKPVEDFRIRTAFGGTVTLISSVVIGILFFNELMTYLSTEIVEELLVDTTVGDARLKINFDIVFPAMACSFLSVDAMDASGQFQNDVTENVWKEPIHWSENNVGTTTPTVQQSKARNCGSCYGAETSEIQCCNSCDDVMEAYKRKGWALNSMDSVEQCRDREWVQKLHHSLNQGCHVYGWLEVSKVTGNFHIAPGSSVKDVHVHVHNLHQLGPSAFNTSHTIKHFSFGQSFPGKKFPLDGETVIANKGERTV
Length542
PositionMiddle
OrganismTrichinella papuae
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Nematoda> Enoplea> Dorylaimia> Trichinellida> Trichinellidae> Trichinella.
Aromaticity0.11
Grand average of hydropathy-0.432
Instability index48.02
Isoelectric point6.31
Molecular weight63159.22
Publications









Function






Annotated function

Possible role in transport between endoplasmic reticulum and
Golgi. 


GO - Cellular Component
endoplasmic reticulum-Golgi intermediate compartment membrane	GO:0033116	IEA:UniProtKB-SubCell
integral component of membrane	GO:0016021	IEA:UniProtKB-KW
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription, DNA-templated	GO:0006355	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP06366
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      51.96|      14|      15|     423|     437|       1
---------------------------------------------------------------------------
  423-  437 (23.76/23.58)	NSCDDVMEAYKRKgW
  440-  453 (28.19/21.34)	NSMDSVEQCRDRE.W
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     302.69|      64|      69|      60|     124|       2
---------------------------------------------------------------------------
   19-   52 (48.91/24.74)	....LEFVQCL...................ANPNYL....N.......YLAQRDFFKNP.AFINYLKYL
   60-  124 (106.06/65.12)	YAKYLKFPQCLYIlELLQTEEFRTAMMR.VPNSKFLE..DQMLLQWQFYIRKRDSVRLP.SRCETCKYL
  132-  196 (85.27/48.02)	FSETGQSPETTFN.GRGGTKKYRDSELRfIETMENLC..DR.LLEYNLHKEHKNSLRFArGQSETMKTL
  213-  263 (62.45/33.15)	..............ELWDSPSVEITRMK.QDCETILEnnEEAIERW.YYAKQKEPLR.H.YLCENRSFL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      39.89|      13|      16|     479|     492|       3
---------------------------------------------------------------------------
  479-  492 (19.71/16.55)	NFH.IAPgSSVKDVH
  497-  510 (20.18/11.18)	NLHqLGP.SAFNTSH
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP06366 with Med31 domain of Kingdom Metazoa
Unable to open file!