<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP06365

Description U5 small nuclear ribonucleoprotein 40 kDa protein
SequenceMTRHQKNATASTVYSYHERKKDQKASGYGTLEERLEKAALKDFDCCSLTLQRCKDPVVNQDGYLFEYEAILKYILHQKKEIARKSKLYANYLEKKQQEEVEMQNAEYNKKVRKFVASEATPARRMNVEDDSSLATTSTGLGNQKSRSFWVPGSEMAKESAVEKPDTKVLCPVTGKELKMKNLTHIKFTLANGIQESEVFTKKDVYVCALTGDILTNSVPCAVLKTSGNVITVSALEKVVKKDMIDPFNGRKLTDKDIILLQRGGTGFAATNEKLNAKLSRPIFSAIMNHPGNAVAIVHPSKPHEVVSHSEEQKRSSHLMAPIMSLIGHEGEIYAAAFSYDGTMLASGVLWNVYGECENFALLSGHNGAIMELHFSADNNVLFTCSTDKTVRLWDMETGVCIRNFKGHTSFVNSCHPARRGPQLVCSGSDDGTIKVWDKRQKKCIYSFENVYQVTAVTFNDTAEQIVSGGIENDLKIWDIRKESPMFTLRGHGDTVTGLSLSPDGSHVLSNAMDCTVRIWDIRPFAPVNRCVAVLQGAQHNFEKNLLRCAWSPDGMKASSGSADRFVYIWDLNSRRVQYKLPGHFGSVNVTAFHPCEPIVWLSKSTCIFENLAFEHWLLLNGDFSNGDGLLIWRNRPAVVIGRHQNPWLEANLEWAKEADVDVARRHSGGGTVYHDMQNMNVSFLTTNKRYNRLRNLSLVRQTVERITGLQLAINDKHDLLLCGHKISGTAAKLTSNAAYHHLTVMLDVNLKRLSRALNSNIHGVLTNATESRRSSVTSLRQFQPELNYDQLVEAVVEDFARNYESCQVENVFHIDDAHFVNISDNVEQLKSWNWRFGQSPKFVLDRVLRPRSQFECRLRVTVVHGLIERIELIKKNQISAAFSEAALFTGIPFHTDALEQIIISAIHSLMDEGRKNISARKAMLLKEYQVLLQRSVKSIRENFTEIIKMAKIGDDGQVSRLTEYEHELFEMQIRAANMTHAAEALIKMVTDLKQFLILNDFAYINESITTSAVHNQIAQREFRDKLIAVKEEMTYCLQEAEQEYYNTALKNSVSYLKLNF
Length1060
PositionHead
OrganismTrichinella papuae
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Nematoda> Enoplea> Dorylaimia> Trichinellida> Trichinellidae> Trichinella.
Aromaticity0.08
Grand average of hydropathy-0.335
Instability index34.84
Isoelectric point8.28
Molecular weight119807.27
Publications

Function

Annotated function
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro
GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro
GO - Biological Process
cellular protein modification process	GO:0006464	IEA:InterPro
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro

Interaction

Binary Interactions

Repeat regions

Repeats

>MDP06365
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
            10|     402.05|      40|      40|     362|     401|       1
---------------------------------------------------------------------------
  289-  322 (27.86/12.12)	.......HP..GnAVAIVHPSKPHEVV........SH..SEEQKRSS.....HLMA....P.....I
  323-  359 (33.71/16.12)	MSliG..HE..G.EIYAAAFSYDGTML...............ASGVL.....WNV.....YGECenF
  362-  401 (63.32/36.35)	LS..G..HN..G.AIMELHFSADNNVLF.......TC..STDKTVRL.....WDME....TGVC..I
  404-  444 (46.98/25.18)	FK..G..HT..S.FVNSCH.PARRGPQL.......VCsgSDDGTIKV.....WDKR....QKKC..I
  445-  485 (39.58/20.13)	YS..F..EN.vY.QVTAVTFNDTAEQIV.......SG..GIENDLKI.....WDIR....KESP..M
  488-  531 (50.05/27.28)	LR..G..HG..D.TVTGLSLSPDGSHVL.......SN..AMDCTVRI.....WDIRpfapVNRC..V
  534-  577 (42.91/22.41)	LQ..GaqHNfeK.NLLRCAWSPDGMKAS.......SG..SADRFVYI.....WDLN....SRRV..Q
  580-  607 (38.56/19.43)	LP..G..HF..G.S...........VNV.......TA..FHPCEPIV.....W.LS....KSTC..I
  611-  662 (30.50/13.92)	LA..F..EH..W.LLLNGDFSNGDGLLIwrnrpavVI..GRHQNPWLeanleWAKE....ADVD..V
  663-  696 (28.58/12.61)	AR..R..HS..G.GGTVYHDMQNMNVSF.......LT..TNKRYNRL.....RNL............
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      98.12|      30|      36|     108|     142|       3
---------------------------------------------------------------------------
  110-  139 (49.01/41.76)	KVRKFVASEATPARRMNVE.DDSSLATTSTG
  144-  174 (49.11/25.54)	KSRSFWVPGSEMAKESAVEkPDTKVLCPVTG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      86.41|      28|      36|     188|     223|       4
---------------------------------------------------------------------------
  188-  216 (42.98/45.88)	TLANGIQES..EVFTKKDVyVCALTGDILTN
  225-  254 (43.43/23.34)	TSGNVITVSalEKVVKKDM.IDPFNGRKLTD
---------------------------------------------------------------------------




Explaination for Stockholm format The "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space.

#=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00)

#=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column. It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column. This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.

#=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.

Alignment of MDP06365 with Med22 domain of Kingdom Metazoa

Intrinsically Disordered Regions

IDR SequenceStartStop
NANANA

Molecular Recognition Features

MoRF SequenceStartStop
1) TVYSYHER
12
19