<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP06355

Description Mediator of RNA polymerase II transcription subunit 26 (Fragment)
SequenceMYNCVFENTEILFKRMQALPVERLKVRLLSCLDREKKVNNVAKACEAMDAIESVSMTKESLESSRLGLLINEVRRSNQLLHPDLAKRCRLLIKKWRKLISTTTTTTTTTTTTTTTTQPITDNGVDTSATVTDGVATVAADDRAIRIRIKLGTSVNEATILGGQEKKHHHHHHHHHNQQQQKVDNFGIEQAENRRKRKHSSHNAVNNNTKLNGITKTHLSAIGSGSGGGSTVSKQCKSRSSASSCSRPSQPVPFPRPRPRPAPLPSAKTSPPPPPPTPPQPPPPLPPPPPSAPTPPPPPPPPPPPPSSPPPLPPSSPPPPPPPPPPPPPSTSPSLITTITTTTPSSSRPPKLKTTAELVADLTKCYPEELLVNISTSIGVDSTNALQQHTSNSGDDAPSPALSFSAVEHQPSGTGTEVNKLELLEKYLAEDTDQQRQHHDNVVAGSSSGACTTSSSSSVDSDTTSSRSSTPSRDKIVRSSDDGDDAPAVPGPAPSPGDGAKPALDAACGRPTMRLLPPVDRSMLHRLDEIVPPTKSRVSSLKYLDDYSNEPPEQTRTLAPFEQSLRMVPSELRQLHSRVLVKTTDGRRVLALPYLDIGLPDFLEYNNLPATTDQLLSWETMR
Length621
PositionUnknown
OrganismTrichinella papuae
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Nematoda> Enoplea> Dorylaimia> Trichinellida> Trichinellidae> Trichinella.
Aromaticity0.03
Grand average of hydropathy-0.685
Instability index70.23
Isoelectric point8.92
Molecular weight66954.61
Publications









Function






Annotated function


GO - Cellular Component
nucleus	GO:0005634	IEA:InterPro

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP06355
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     152.22|      22|      22|     285|     306|       1
---------------------------------------------------------------------------
  263-  287 (41.79/ 9.34)	LPSAKTsPPPPPPtPPQPPPPlPPP
  288-  310 (55.60/14.67)	PPSAPT.PPPPPP.PPPPPPSsPPP
  312-  332 (54.83/14.37)	PPSSP..PPPPPP.PPPPPPS.TSP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      37.88|      12|      19|     173|     184|       2
---------------------------------------------------------------------------
  173-  184 (20.61/12.05)	HHHNQQQQKVDN
  189-  200 (17.26/ 9.13)	QAENRRKRKHSS
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     139.61|      41|     225|     222|     262|       3
---------------------------------------------------------------------------
  222-  262 (81.00/31.47)	GSGSGGGST......VSKQCKSRSSASS......CS.....RPSQPVPFPRPRPRPAP
  444-  501 (58.61/20.82)	GSSSGACTTsssssvDSDTTSSRSSTPSrdkivrSSddgddAPAVPGPAPSPGDGAKP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      67.33|      22|      48|     523|     544|       4
---------------------------------------------------------------------------
  523-  544 (38.48/21.08)	LHRLDE..IV.PPTKSRVSSLKYLD
  571-  595 (28.84/14.11)	LRQLHSrvLVkTTDGRRVLALPYLD
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     143.77|      47|     224|     106|     155|       5
---------------------------------------------------------------------------
  106-  155 (70.43/41.53)	TTTTTTTTTTTQPitdNGVDTSATVTDGVATVAADDRAIRIRIKLGT.SVN
  336-  383 (73.34/36.96)	TTITTTTPSSSRP...PKLKTTAELVADLTKCYPEELLVNISTSIGVdSTN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      66.15|      19|      39|     504|     522|       6
---------------------------------------------------------------------------
  504-  522 (35.91/19.50)	DAACGRP.TMRLLPPVDRSM
  545-  564 (30.25/15.17)	DYSNEPPeQTRTLAPFEQSL
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP06355 with Med26 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) NEATILGGQEKKHHHHHHHHHNQQQQKVDNFGIEQAENRRKRKHSSHNAVNNNTKLNGITKTHLSAIGSGSGGGSTVSKQCKSRSSASSCSRPSQPVPFPRPRPRPAPLPSAKTSPPPPPPTPPQPPPPLPPPPPSAPTPPPPPPPPPPPPSSPPPLPPSSPPPPPPPPPPPPPSTSPSLITTITTTTPSSSRPPKLKTTAELVADLTKCYPEELLVNISTSIGVDSTNALQQHTSNSGDDAPSPALSFSAVEHQPSGTGTEVNKLELLEKYLAEDTDQQRQHHDNVVAGSSSGACTTSSSSSVDSDTTSSRSSTPSRDKIVRSSDDGDDAPAVPGPAPSPGDGAKPALDAACGRPTMRLLPPVDRSMLHRLDEIV
2) VSSLKYLDDYSNEPPEQTRTLAPFEQSLRM
155
537
530
566










Molecular Recognition Features






MoRF SequenceStartStop




1) KLELLEKYLA
2) SLKYLDDY
419
539
428
546