<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP06349

Description Mediator of RNA polymerase II transcription subunit 24
SequenceMIEALGISLSPMDRLLIDAWRECWPDVVFMRQLRLRIEITDENIEQLSSVLLHYSTLSEMPNRLMLKYLKFCLDTQVVPSVTFLNVVNSYRSYEKVECINEILPLVIYCFEKLNCDFCDANVCVRTSILVMNTVLWILAYVDYLLTANNFPPLSHFLSLVFTLKENKFVQFCNYFVCWELSEFHDQIKASIRNIKDKIEANRQLIQPDLSDNMLTFLSFLDIEKNSYNNLFSANRNEILAQSVRASNSRIPSVVISLSGIFAHVQSMKGIAAMVEALKVAKDIQGESWLNVIHDLIMGGILQQHDDSTTLPFSVSSSYLYLRIPRLLSQLVAEDVPKETLLGSLRRIATSEAVLNISDTKARCNTLQAFLNVLSELGILQESEKDTLMAIRDEMRKELYVQEGQPTINLVLRAEFTLQSIVKAFDAHQALERWPQMLNTMMSGKSLLYICAAAISIDQLNLLAERLIKITETYKEVVPVVEDAQKSVPPSHDLFDMSFLLLHRLSQYYSTTTCLRPGDPFFKTWYFSSAIDLVRNMFDPADLPQLLNNVPLDLELASDVLSRLRVGQPGWLNIRTWYCIIDLIPSIVQLVLNEVLLDTISIEELKHIFSGLLFLNIHGVSCMCSPLLCFAQYVALQKTDEATKLANSLFSFFESITPSDAERNRQTDRQTFMVNSAKKLFSAYRELPVTLMHVLRMNRAPPQLTHSSDDHFPVIGKPENIRSFFAASERAGYLTAALIARIIVLVESEQYDSWLSAFIEALQKVNTMQGMEKWCNLNLACCFIKPKECTLALIPLLSNYVLHDDRDLFCVAPRGNILAFFLVKLYLIALRHTNATDVDKAETAGCSMDEYSLQNNTNSTADRTAVIASLRELFNSKFEVVRSGELCPTVAFVSNFLYCLSEYSTPEAELIKNEIPMHLIFSLLRADPDILSMRTVLRLFDLKDEIQRRKALQTAFLLKRKQYI
Length963
PositionTail
OrganismTrichinella papuae
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Nematoda> Enoplea> Dorylaimia> Trichinellida> Trichinellidae> Trichinella.
Aromaticity0.09
Grand average of hydropathy0.113
Instability index46.30
Isoelectric point5.56
Molecular weight109830.26
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP06349
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      34.29|       9|      49|     523|     533|       1
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  523-  533 (13.91/13.24)	TWYfsSAIDLV
  575-  583 (20.38/11.18)	TWY..CIIDLI
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     109.89|      30|      51|       9|      59|       2
---------------------------------------------------------------------------
   11-   41 (53.80/41.26)	PMDRLLIDAWRECW.....PDVVFMRQ.LRLrIEITD
   62-   84 (11.81/32.21)	..NRLMLKYLKFCLdtqvvPSVTFL............
  915-  943 (44.28/21.80)	PM.HLIFSLLRAD......PDILSMRTvLRL.FDLKD
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     136.87|      38|      51|      90|     127|       3
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   90-  127 (70.62/44.46)	YRSY....EKVECINEILPLVIYCFEKLNCDFCDANVCVRTS
  140-  181 (66.25/41.26)	YVDYlltaNNFPPLSHFLSLVFTLKENKFVQFCNYFVCWELS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     203.66|      74|     151|     208|     289|       5
---------------------------------------------------------------------------
  208-  289 (102.63/95.63)	DLSDN.........MLTFLSFLDIEKNSYNNLFSANRNEiLAQSVRASNSRiPSVVISLSGIFAhVQSM.KGIAA.........MVEALkvakdIQGESWL
  355-  447 (101.03/68.89)	NISDTkarcntlqaFLNVLSELGILQESEKDTLMAIRDE.MRKELYVQEGQ.PTINLVLRAEFT.LQSIvKAFDAhqalerwpqMLNTM.....MSGKSLL
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP06349 with Med24 domain of Kingdom Metazoa
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