<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP06301

Description Vacuolar protein sorting-associated protein 11-like protein (Fragment)
SequenceMSQQNQNSFIQTFPLPPRPLNSNGNNLDANYGYPQGIGPSSVSSPIQSLVNSFGSRREVPSPSPASVSESTNVAPGKTTQADESQQEHHAEREAWSAQGSKAFNVNPFFAFSMSQILQSNDNNGPLALCIIGRDFTREVINRTCDICGALKSLQLPTAPEAVKQHQDKLQRINESLKQVNIILERLEAIDRKIDNFRKELLPADAEDHLKDLVTYDGKNEWLRKLTEERKSREVFTQTKQQYDEVKKELETHAPSCSARSFNFCSLKLAQFDPREFGLRLKPYIANSDDIHIPFRRPFFSCTNSLIYPDYNSYFIPIIRNLSSKKSKNDSVSESLVKRRVSFNFSAVYSQVVNQCSSTEKSPTHYFERGKPNWDQLQHVIYRLSETVPTFFLRRLDYTFYSDDVLFLNRICGSEVKGLRNYWLHLATLSVLSRIPCPYIEMKILNCMPIVEEGSVHLRWRVLYLTVPEFLYVVVRERSADIETLRRNARWFDGFSYFYVGSDGLVYKHVADRVMRDPEEIAANSKRVGLLNRLLGSSARSPIWKQFNLDKEKKNLVDSYGLSIQLILATLAFASLIVKRLLEPKQTRRPWTIWFFDTSKQAVGSSVIHAMNIFLAGVFRGDPCTWYFVSFLLDSTLGLLIIYTGVKLVTAAASCRKDWSTLRFGEYGDPPQCRPWLHQCLAFVILSVIEKFFVTLLLLMRFWKSVREIALSPIRNPKVEVTLVILVFPFLINTIMFWVVDNFTMKRRAVSKKFNSNNSNSLIIANNGSSSSGIRRVHDESAVKLLDEYDNNSQQNDALALFPADNILQHRNSSTLAGIFVFFIHFNSDCESSTIIMASSLFQSWRRLVFFDRQLIADVENADESFTEFKDLNIACVAWKSNRVFIGEVDGGVHMYDKDFNDTYFKAYKVNLSLLYCPRSSDSLVSIGEDDNGVNPYLKVWLLDKLDKQGKPFAVRCSKTSPGNRPVKVTSVAVDSSGQLMVVGFEDSSILLYRGDVCKEKQPKSQLIRDGSTCASEGSIVGMELCDHSSQAVILYVVTTRFTFSFTISFKEKDITKTVLEMEGLHMRRCWALAGEELKNQFVVARNMGFYFYQPEEKAYEASFPDISEVFIAWNFIFILCMESGKLFRLKEMSIESQLDILFRKNLFDLAIRVSERNNVSKRELSNIYQFYGDYFYKKRDYSNALKQYMRTIGTLDTSYVIRKLLDAHRIENLAEYLEAVFHAKLGTVDHSNVLLSCYIKMNAIDKINSFIQNKETVAPLDVEAAVKLFRKFGLYRQAAFLTKRHGYPKRCLDLLVSDLKDFKQAINYISSLESDVIAEFFTRYSKLLLENVPEETMTLLGEILKRDGCSEKNWVQSVVLRLIAHPDRLEAFLEQSLMANKVDVKLYNLLLYAYLRRYSSTMENDVAKEQISRKIDQLLKNISSDSQSLLEALRFCYQWAYHPGILYLLERQKMYSHLLKHQMFLKDYDSVISACLKYGDRRSGDKTLWSFALQYFSEDPTISEEYVKKLLTSSELTGDVHPMLAVQTLAKSKTLTFACVKDFLSHWVDKESKSIEMDEQDSLRLCNEIKRTEAIIDDIQKNPQIFQMSKCTACDIILETPTVHFLCKHSYHQHCFENYAESEAECPVCLLDKKRFQNQCKTDSSTSSEALNHSFKEELMNTNNVIGTLTSYFGKTLFPDKDVDAENCEIHQQDTSKSVQSLNPFEVW
Length1708
PositionHead
OrganismTrichinella nativa
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Nematoda> Enoplea> Dorylaimia> Trichinellida> Trichinellidae> Trichinella.
Aromaticity0.11
Grand average of hydropathy-0.263
Instability index48.18
Isoelectric point7.84
Molecular weight196184.01
Publications

Function

Annotated function
GO - Cellular Component
integral component of membrane	GO:0016021	IEA:UniProtKB-KW
nucleus	GO:0005634	IEA:UniProtKB-SubCell
GO - Biological Function
metal ion binding	GO:0046872	IEA:UniProtKB-KW
GO - Biological Process
intracellular protein transport	GO:0006886	IEA:UniProtKB-UniRule
vesicle-mediated transport	GO:0016192	IEA:InterPro

Interaction

Binary Interactions

Repeat regions

Repeats
>MDP06301
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     223.34|      72|      83|     516|     590|       1
---------------------------------------------------------------------------
  516-  590 (112.72/83.57)	DPEEIAANSKRVGLLNRLLGSSARS.P.IWK..QFNLDKEKKNLVDSYGlsIQLILATLA....FASLIVKRLLEPKQTrRPW
  596-  675 (110.62/71.81)	DTSKQAVGSSVIHAMNIFLAGVFRGdPcTWYfvSFLLDSTLGLLIIYTG..VKLVTAAAScrkdWSTLRFGEYGDPPQC.RPW
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     107.52|      23|      83|    1076|    1099|       2
---------------------------------------------------------------------------
 1076- 1099 (37.72/31.48)	ELKNQFvVARNMGFYFYQPEE.....KAY
 1105- 1127 (37.90/26.18)	DISEVF.IAWNFIFILCMESG.....KLF
 1163- 1188 (31.90/20.64)	ELSN...IYQFYGDYFYKKRDysnalKQY
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     215.82|      76|     120|    1192|    1283|       3
---------------------------------------------------------------------------
 1192- 1283 (97.50/108.36)	IGTLDTSYviRKLLdahrIENLAE....YLEAVFhaKLGTVDHSNVLLSCYIKMNA.IDKINSFIQNKETVAPLDVeaavKLFrKFGLYrqaAFLTK
 1317- 1397 (118.33/80.20)	IAEFFTRY..SKLL....LENVPEetmtLLGEIL..KRDGCSEKNWVQSVVLRLIAhPDRLEAFLEQSLMANKVDV....KLY.NLLLY...AYLRR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     113.19|      34|     667|     853|     898|       4
---------------------------------------------------------------------------
  864-  897 (64.65/53.86)	SF..TEFK..DLNIA...CVAWKSNRVFIGEVDGGVHMYDK
  898-  938 (48.55/21.95)	DFndTYFKayKVNLSllyCPRSSDSLVSIGEDDNGVNPYLK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      78.90|      25|    1240|     187|     212|       7
---------------------------------------------------------------------------
  187-  212 (38.63/27.55)	EAIDRKIDNFRKElLPADAEDHLKDL
 1409- 1433 (40.27/24.22)	EQISRKIDQLLKN.ISSDSQSLLEAL
---------------------------------------------------------------------------




Explaination for Stockholm format The "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space.

#=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00)

#=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column. It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column. This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.

#=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.

Alignment of MDP06301 with Med30 domain of Kingdom Metazoa

Intrinsically Disordered Regions

IDR SequenceStartStop
1) MSQQNQNSFIQTFPLPPRPLNSNGNNLDANYGYPQGIG
2) SPIQSLVNSFGSRREVPSPSPASVSESTNVAPGKTTQADESQQEHHAEREAWSA
1
44
38
97

Molecular Recognition Features

MoRF SequenceStartStop
1) FIQTFP
9
14