<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP06276

Description Coiled-coil domain-containing protein 47
SequenceMMELRDVLYATPYRPKSSAAHVFESIKPRPILNITPECSEDEDCNSGTSGKDSDKMLKREIAYSSPNSCSRGKQLNKPFLNTCEALIEKIKRVKKIDPSTLAKEQIRRNEHYYQKIAMKKILLVLYLDKKMQEIDKNFINSVGSIVQNIKSIQSSISEVLAKLQMVEQPSLLNSFRVISSQFNSVLQLLRSDRASHFKNYVFLPIRLSVEVDADLEAATENRLHAWTHAVVPDYLRTKPDPQVEQKDQQISNQVQQRICNPESLLKQVTAFNRCLNCILDSLNASIRDSEMDGRKTSKTSDSEDTALLVAAILKGQNVKPAYSATPTSSRGSSGDSGHSKSSKAPKCSIEINQFTIKRQEKVRRKVCIWMFFLSCLFELVELSVKQVSQIDDNEFAEFEEFDVELDASVDADFMENNVNERETPPVDTASIGAKRSPANAEQKRNDAPNNNFNDDDYGIVEDESVDDFSHLLDENEFENFPDERKPGKQNAGPSKPVTQLKITDTKNHSLAVAWFDSNRPFLEENFSIVGDDGISPEVTKNVLIKESDNHYIVWCSGRQGCIGMEIHLKLIKRQDLLSLIFYIIRPKFDIIEIKIILNPEEMDPFVFALGTKRSAIKNAKEIMDLNLYCSEKKNVEKLGLPSSYVLHSEIGEVTTGLLDSKMVSALCKYKDVVDYIHISDQFVGIKPIEMENMAKPPETAKVVMICLNIPGQLRATEEDVCTLQPLMIFIFHVLEKVRRFRLTREGKQKADKNRQYVEESFLKTTHAQRQEAAQQRREERARERKERLMAEEDPERQRKLEKQELKRELKKKQPRVKQIKIKAM
Length824
PositionHead
OrganismTrichinella zimbabwensis
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Nematoda> Enoplea> Dorylaimia> Trichinellida> Trichinellidae> Trichinella.
Aromaticity0.06
Grand average of hydropathy-0.564
Instability index48.97
Isoelectric point6.94
Molecular weight94225.58
Publications









Function






Annotated function


GO - Cellular Component
integral component of membrane	GO:0016021	IEA:UniProtKB-KW
mediator complex	GO:0016592	IEA:InterPro
rough endoplasmic reticulum membrane	GO:0030867	IEA:UniProtKB-SubCell

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP06276
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      55.74|      18|      25|     530|     548|       1
---------------------------------------------------------------------------
  530-  548 (27.32/19.83)	GDDG.ISPEVTKNvLIKESD
  557-  575 (28.42/16.06)	GRQGcIGMEIHLK.LIKRQD
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      53.03|      17|      25|     144|     160|       2
---------------------------------------------------------------------------
  144-  160 (26.01/17.71)	SIVQNIKSIQSSISEVL
  170-  186 (27.02/18.69)	SLLNSFRVISSQFNSVL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      76.58|      24|      25|     747|     770|       3
---------------------------------------------------------------------------
  747-  770 (38.18/22.56)	KQKADKNRQYVEESFLKTTHAQRQ
  774-  797 (38.40/22.73)	QQRREERARERKERLMAEEDPERQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     138.25|      43|     254|      62|     108|       4
---------------------------------------------------------------------------
   62-  108 (68.97/48.42)	AYSSPNSCSRGKQLNKPFLNTCEALIEKIkrvkKIDPSTLAK.EQIRR
  321-  364 (69.28/40.35)	AYSATPTSSRGSSGDSGHSKSSKAPKCSI....EINQFTIKRqEKVRR
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP06276 with Med8 domain of Kingdom Metazoa
Unable to open file!