<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP06270

Description Mediator of RNA polymerase II transcription subunit 24
SequenceMIEALGPSLSPMDRLLIDAWRECWPDVVFMRQLRLRIDITDENVEQLSSVLLHYSTLSEMPNRLMLKYLKFCLDTQVVPCVTFLNVVNSYRSYEKVECINEILPLVIYCFEKLNCDFCDANVCVRTSILVMNTVLWILAYVDYLLTANNFPPLSHFLSLVFTLKENKFVQFCNYFVCWELSEFHDQIKASIRNIKDKIEANRQFIQPDLSDNMLTFLSFLDIEKNSYNNLFSANRNEILAQSVRASNSRIPSVVISLSGIFAHVQSMKGIAAMVEALKVAKDIQGESWLNVIHDLIMGGILQQHDDSTTLPFSVSSSYLYLRIPRLLSQLVAEDVPKETLLGSLRRIATSEAVLNISDTKARCNTLQAFLNVLSELGILQESEKDTLMAIRDEMRKELYVQEGQPTINLVLRAEFTLQSIVKAFDAHQALERWPQMLNTMMSGKSLLYICAAAISIDQLNLLAERLIKITETYKEVVPVVEDAQKSVPPSHDLFDMSFLLLHRLSQYYSTTTCLRPGDPFFKTWYFSSAIDLVRNMFDPADLPQLLNNVPLDLELASDVLSRLRVGQPGWLNIRTWYCIIDLIPSIVQLVLNEVLLDTISIEELKHIFSGLLFLNIHGVSCMCSPLLCFAQYVALQKTDEATKLANSLFSFFESITPSDAERNRQTDRQTFMVNSAKKLFSAYRELPVTLMHVLRMNRAPPQLTHSSDDHFPVIGKPENIRSFFAASERAGYLTAALIARIIVLVESEQYDSWLSAFIEALQKVNTMQGMEKWCNLNLACCFIKPKECTLALIPLLSNYVLHDDRDLFCVAPRGNILAFFLVKLYLIALRHTNATAVDKAETAGCSMDEYSLQNNTNSTADRSAVIASLRELFNSKFEVVRSGELCPTVAFVSNFLYCLSEYSTPEAELIKNEIPMHLIFSLLRADPDILSMRTVLRLFDLKDEIQRRKALQTAFLLKRKQYI
Length963
PositionTail
OrganismTrichinella zimbabwensis
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Nematoda> Enoplea> Dorylaimia> Trichinellida> Trichinellidae> Trichinella.
Aromaticity0.09
Grand average of hydropathy0.114
Instability index45.04
Isoelectric point5.61
Molecular weight109778.21
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP06270
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      34.29|       9|      49|     523|     533|       1
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  523-  533 (13.91/15.76)	TWYfsSAIDLV
  575-  583 (20.38/13.33)	TWY..CIIDLI
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     189.93|      51|     151|      23|      74|       2
---------------------------------------------------------------------------
    9-   38 (37.86/15.62)	..................LSPM.DRLLIDAWR.......eCWPDVVFMRQLRLRID
   39-   74 (45.73/24.21)	ITDENVEQLSSVLLHYSTLSEMpNRLMLKYLKFCLD....................
  145-  192 (71.37/34.93)	LTANNFPPLSHFLSLVFTLKE..N....KFVQFC..nyfvCWELSEFHDQIKASIR
  193-  221 (34.96/13.95)	NIKDKIEA.NRQFIQ.PDLS...DN.MLTFLSF.LD....................
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     168.65|      47|      50|     365|     414|       3
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  327-  372 (57.67/40.00)	LSQL.VAEDVPK..ETLLG...SLRR...IATSEAVLN.ISdtkARCN.TLQAFLNV
  373-  423 (63.19/53.50)	LSELGILQESEK..DTLMAirdEMRKELYVQEGQPTIN.LV...LRAEfTLQSIVKA
  424-  466 (47.79/31.79)	FDAHQALERWPQmlNTMMS....GKSLLYICAAAISIDqLN...LLAE.RL......
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      55.20|      16|     331|     301|     316|       4
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  301-  316 (28.77/20.04)	LQQHDDSTTLPFSVSS
  635-  650 (26.44/17.80)	LQKTDEATKLANSLFS
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     204.60|      66|     462|     225|     290|       5
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  225-  290 (111.27/66.33)	NSYNNLFSANRN.EILAQSVRASNSRIPSVVISLSGIFAHVQSMKGI..................................AAMVEALKVAKDIQG.ESWLN
  674-  775 (93.32/54.58)	NSAKKLFSAYRElPVTLMHVLRMNRAPPQLTHSSDDHFPVIGKPENIrsffaaseragyltaaliariivlveseqydswlSAFIEALQKVNTMQGmEKWCN
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     131.85|      40|     688|      97|     139|       6
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   97-  139 (69.80/48.01)	ECINEILPLVI.YCFEKLNCDFCdanVCVRTSILVMNTV.LWILA
  787-  828 (62.05/35.42)	ECTLALIPLLSnYVLHDDRDLFC...VAPRGNILAFFLVkLYLIA
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP06270 with Med24 domain of Kingdom Metazoa
Unable to open file!