<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP06266

Description Endoplasmic reticulum-Golgi intermediate compartment protein 3
SequenceMLNNIESEEEQRIRFQVELEFVQCLANPNYLNYLAQRDFFKNPAFINYLKYLLYWKRQEYAKYLKFPQCLYILELLQTEEFRTAMMRVPNSKFLEDQMLLQWQFYIRKRDSVRLPSRCETCKYLALELEARFSETGQSPETTFNGRGGTKKYRDSELRFIETMENLCDRLLEYNLHKEHKNSLRFARGQSETMKTLHGLVNRGVQVELGLPYELWDSPSVEVTRMKQDCETILENNEEAIERCLFQSFLHIILHTVVINFRMLSQVIRQMRRLDAYSKPVEDFRIRTAFGGTVTLISSVVIGILFFNELMTYLSTEIVEELLVDTTVGDARLKINFDIVFPAMACSFLSVDAMDASGQFQNDVTENVWKEPIHWSENNVGTTTPTVQQSKARNCGSCYGAETSEIQCCNSCDDVMEAYKRKGWALNSMDSVEQCRDREWVQKLHHSLNQGCHVYGWLEVSKVTGNFHIAPGSSVKDVHVHVHNLHQLGPSAFNTSHTIKHFSFGQSFPGKKFPLDGETVIANKGERTV
Length528
PositionMiddle
OrganismTrichinella zimbabwensis
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Nematoda> Enoplea> Dorylaimia> Trichinellida> Trichinellidae> Trichinella.
Aromaticity0.11
Grand average of hydropathy-0.379
Instability index44.72
Isoelectric point6.10
Molecular weight61257.10
Publications









Function






Annotated function

Possible role in transport between endoplasmic reticulum and
Golgi. 


GO - Cellular Component
endoplasmic reticulum-Golgi intermediate compartment membrane	GO:0033116	IEA:UniProtKB-SubCell
integral component of membrane	GO:0016021	IEA:UniProtKB-KW
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription, DNA-templated	GO:0006355	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP06266
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      51.96|      14|      15|     409|     423|       1
---------------------------------------------------------------------------
  409-  423 (23.76/19.13)	NSCDDVMEAYKRKgW
  426-  439 (28.19/17.29)	NSMDSVEQCRDRE.W
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      52.21|      15|      16|      20|      34|       2
---------------------------------------------------------------------------
   25-   42 (22.49/12.41)	LANPNYLNYLaqrDFFKN
   55-   69 (29.72/18.49)	WKRQEYAKYL...KFPQC
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     148.29|      46|      71|      78|     124|       3
---------------------------------------------------------------------------
   78-  124 (78.53/70.59)	TEEFRTAMMR.VPNSKFLEDQmLLQWQFYIRKRDSVRLP.SRCETCKYL
  149-  196 (69.76/56.25)	TKKYRDSELRfIETMENLCDR.LLEYNLHKEHKNSLRFArGQSETMKTL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      39.89|      13|      16|     465|     478|       4
---------------------------------------------------------------------------
  465-  478 (19.71/15.76)	NFH.IAPgSSVKDVH
  483-  496 (20.18/10.69)	NLHqLGP.SAFNTSH
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP06266 with Med31 domain of Kingdom Metazoa
Unable to open file!