<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP06258

Description Mediator of RNA polymerase II transcription subunit 26 (Fragment)
SequenceLKHGNSVQANASVAGGAFKGSPVKLLGQREEALNGPILDTVDLREQQSNIMLLFFFSFQVNNVAKACEAMDAIESVSMTKESLESSRLGLLINEVRRSNQLLHPDLAKRCRLLIKKWRKLISTTTTTTTATTTTTQPITDNGVDTSATVTDGVATVAADDRAIRIRIKLGTSVNEATILGGQEKKHHHHHHHHHNHNQQQQQQQKVDNFGIEQAENRRKRKHSSHNAVNNNTKLNGITKTHLSAIGGGSGGGSTVSKQSKQCKSRSSASCSRPSQPVPFTRPRPRPAPLPSAKTSPPPPPTPPQPPPLPPPSSAPTPPPPPPPPPPPPSSPPPLPPSSPPPPPSSPPPPPPPPPPPPPPSTSPSLITTTTPSSSRPPKLKTTAELVADLTKCYPEELLVNISTSIGVDSTNALQQATSNSGDDAPSPALSFSAVEHQPSGTGAEVNKLELLEKYLAEDTDQQRQHHDHVVAGSSSGACTTSSSSSVDSDTTSSRSSTPSRDKIVRSSDDGDDAPRPGPAPSPGDGAKPALGAACGLPTMRLLPPVDRSMLHRLDEIVPPTKSRVSSLKYLDDYSNEPPEQTRTLAPFEQSLRMVPSELRQLHSRVLVKTTDGRRVLALPYLDIGLPDFLEYDNLPATTDQLLSWETMRW
Length649
PositionUnknown
OrganismTrichinella zimbabwensis
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Nematoda> Enoplea> Dorylaimia> Trichinellida> Trichinellidae> Trichinella.
Aromaticity0.03
Grand average of hydropathy-0.674
Instability index72.52
Isoelectric point8.82
Molecular weight69501.13
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP06258
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     159.80|      28|      30|     296|     325|       1
---------------------------------------------------------------------------
  273-  301 (48.22/ 8.66)	PSQPVPFTRPR....PRPAPLPSAktsPPPPPT
  302-  329 (57.21/15.14)	PPQPPPLPPPSSaPtPPPPPPPPP.....PPPS
  330-  353 (54.37/10.56)	..SPPPLPP.SS.P..PPPPSSPP...PPPPPP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     100.10|      31|      50|     539|     571|       2
---------------------------------------------------------------------------
  539-  571 (50.88/35.24)	MRLLPPVDRSMLHRLdeIVPPTKS.RVSSLKYLD
  591-  622 (49.22/28.02)	LRMVPSELRQLHSRV..LVKTTDGrRVLALPYLD
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      52.91|      15|      19|     356|     370|       3
---------------------------------------------------------------------------
  356-  370 (28.05/10.88)	PPPPSTSPSLITTTT
  376-  390 (24.85/ 8.84)	PPKLKTTAELVADLT
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      46.37|      14|      34|     182|     195|       4
---------------------------------------------------------------------------
  182-  195 (30.87/17.97)	QEK...............KHHHHHHHHHN
  203-  231 (15.50/ 6.17)	QQKvdnfgieqaenrrkrKHSSHNAVNNN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     120.03|      26|      86|     418|     443|       6
---------------------------------------------------------------------------
  418-  443 (45.16/17.65)	SNSGDDAPSPALSFSAVEHQPSGTGA
  471-  493 (28.51/ 8.51)	AGSSSGACTTS.SSSSVDSDTTSS..
  507-  532 (46.35/18.30)	SDDGDDAPRPGPAPSPGDGAKPALGA
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP06258 with Med26 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) NEATILGGQEKKHHHHHHHHHNHNQQQQQQQKVDNFGIEQAENRRKRKHSSHNAVNNNTKLNGITKTHLSAIGGGSGGGSTVSKQSKQCKSRSSASCSRPSQPVPFTRPRPRPAPLPSAKTSPPPPPTPPQPPPLPPPSSAPTPPPPPPPPPPPPSSPPPLPPSSPPPPPSSPPPPPPPPPPPPPPSTSPSLITTTTPSSSRPPKLKTTAELVADLTKCYPEELLVNISTSIGVDSTNALQQATSNSGDDAPSPALSFSAVEHQPSGTGAEVNKLELLEKYLAEDTDQQRQHHDHVVAGSSSGACTTSSSSSVDSDTTSSRSSTPSRDKIVRSSDDGDDAPRPGPAPSPGDGAKPALGAACGLPT
174
538










Molecular Recognition Features






MoRF SequenceStartStop




1) KLELLEKYLA
2) LKYLDDY
447
567
456
573