<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP06253

Description Ectonucleoside triphosphate diphosphohydrolase 2
SequenceMDEGRKNISARKAMLLKEYQVLLQRSVKSIRENFTEIIKMAKIGDDGQVSRLTEYEHELFEMQIRAANMTHAAEALIKMVTDLKQFLILNDFAYINESITTSAVHNQIAQREFRDKLIAVKEEMAYCLQEAEQEYYNTALKNSVSVLDLFEIEFLRIKMTLDEFGTELYVDPWQTFVSIKGKLRKRAFRSPNLVEVVKDYEALANRLLDENCTEYSALCRMNMAKCKNQLGNIDQEAVEYRTAGRLYIRAEKEKESVENRLSMECLYMAMHCYSEAIRLHLSQGQKLLAASLLIELGKELACMQHPEDAIQNFERAVHLLDTHPHAVGHALRWKLCVETSVGFLADARRTSNFYRQIVESWPNSGSRKLHLNELEIITVMLLLALKPIKSEMNDFEKRLLQRYSDETDEALFTNDGSLLPNDSYIISVEIYLQLKSFVLAINNNDPSAADIALTAMHHHNVKLVHSTGSDASVPLRVLIKSLFYNESSVSLEVDSDFKVKDVINAYAYRTGRNEKDEEFVLRFHDHSSLNSEDVLHVLGVYNDEELIISVRGEDSRRSRNSWWWLGSVALLISLVGLIAVSVLFALSGDLPDEFGIIIDAGSSHSGLYIYTWNGRKNKTGVIKQYAPSCSTEIGISSFTDNPADAGNSLMFCLNNASATVPSKRHSATAMYLAATAGMRILELRDPLSSCKILSAVSNTMHSYNFLYKNASIISGIDEGIYGWITSNFLSHRLMNSASRLNDIRPLTFGAMDLGGASTQIIFEINTSEFTERGHDKSTAATSLYATQLYHERDK
Length794
PositionHead
OrganismTrichinella zimbabwensis
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Nematoda> Enoplea> Dorylaimia> Trichinellida> Trichinellidae> Trichinella.
Aromaticity0.08
Grand average of hydropathy-0.209
Instability index37.75
Isoelectric point5.74
Molecular weight89833.27
Publications









Function






Annotated function


GO - Cellular Component
integral component of membrane	GO:0016021	IEA:UniProtKB-KW
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
ATP binding	GO:0005524	IEA:UniProtKB-KW
hydrolase activity	GO:0016787	IEA:UniProtKB-KW
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP06253
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      81.00|      24|      51|     361|     386|       1
---------------------------------------------------------------------------
  361-  386 (38.10/30.53)	WPNSGSrkLHLNELEIITVMLLLALK
  412-  435 (42.90/27.75)	FTNDGS..LLPNDSYIISVEIYLQLK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     148.57|      51|      77|      77|     135|       3
---------------------------------------------------------------------------
   77-  135 (81.53/74.47)	IKMVtdlkqfliLNDFA...YINESITTSAVHNQIAQREFRD.KLIAV.K..EEMAY.CLQEAEQEY
  157-  215 (67.04/45.90)	IKMT........LDEFGtelYVDPWQTFVSIKGKLRKRAFRSpNLVEVvKdyEALANrLLDENCTEY
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      86.07|      24|      24|     516|     539|       4
---------------------------------------------------------------------------
  516-  539 (41.29/27.34)	DEEFVLRFHDHSSLNSEDVLHVLG
  543-  566 (44.78/30.28)	DEELIISVRGEDSRRSRNSWWWLG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      60.06|      18|     130|     632|     649|       5
---------------------------------------------------------------------------
  632-  649 (32.87/19.92)	EIGISSFTDNPAD...AGNSL
  763-  783 (27.19/15.32)	EINTSEFTERGHDkstAATSL
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP06253 with Med22 domain of Kingdom Metazoa
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