<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP06252

Description Ectonucleoside triphosphate diphosphohydrolase 1
SequenceMDEGRKNISARKAMLLKEYQVLLQRSVKSIRENFTEIIKMAKIGDDGQVSRLTEYEHELFEMQIRAANMTHAAEALIKMVTDLKQFLILNDFAYINESITTSAVHNQIAQREFRDKLIAVKEEMAYCLQEAEQEYYNTALKNSVSVLDLFEIEFLRIKMTLDEFGTELYVDPWQTFVSIKGKLRKRAFRSPNLVEVVKDYEALANRLLDENCTEYSALCRMNMAKCKNQLGNIDQEAVEYRTAGRLYIRAEKEKESVENRLSMECLYMAMHCYSEAIRLHLSQGQKLLAASLLIELGKELACMQHPEDAIQNFERAVHLLDTHPHAVGHALRWKLCVETSVGFLADARRTSNFYRQIVESWPNSGSRKLHLNELEIITVMLLLALKPIKSEMNDFEKRLLQRYSDETDEALFTNDGSLLPNDSYIISVEIYLQLKSFVLAINNNDPSAADIALTAMHHHNVKLVHSTGSDASVPLRVLIKSLFYNESSVSLEVDSDFKVKDVINAYAYRTGRNEKDEEFVLRFHDHSSLNSEDVLHVLGVYNDEELIISVRGEDSRRSRNSWWWLGSVALLISLVGLIAVSVLFALSGDLPDEFGIIIDAGSSHSGLYIYTWNGRKNKTGVIKQYAPSCSTEIGISSFTDNPADAGNSLMFCLNNASATVPSKRHSATAMYLAATAGMRILELRDPLSSCKILSAVSNTMHSYNFLYKNASIISGIDEGIYGWITSNFLSHRLMNSASRLNDIRPLTFGAMDLGGASTQIIFEINTSEFTERNYSLRLFGETYNLFVDSYLCCGLNEVQRIIQAQIVAEDMTNQRPLHPCMPLNYTMNVTSEQIFSMPCSLNQKPNNVLPNYVFRGSSDPHSCLMKIRHMLDTSACSVKKAKIPKPRGEFMAFSGLYWAAKFFNCTSGCSYNKFFENVQNYCEKSWSYIEAAAYPYKKTFLPTYCFIGLYSLTLIKDAYHFSDAQIQDIKFVNEIDSTEIGWTLGFMLNATNQLPEEQPIEHIGLIEFSLITTICCIIRLEQLE
Length1024
PositionHead
OrganismTrichinella zimbabwensis
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Nematoda> Enoplea> Dorylaimia> Trichinellida> Trichinellidae> Trichinella.
Aromaticity0.10
Grand average of hydropathy-0.161
Instability index37.87
Isoelectric point5.70
Molecular weight116337.70
Publications









Function






Annotated function


GO - Cellular Component
integral component of membrane	GO:0016021	IEA:UniProtKB-KW
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
ATP binding	GO:0005524	IEA:UniProtKB-KW
hydrolase activity	GO:0016787	IEA:UniProtKB-KW
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP06252
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      86.07|      24|      24|     516|     539|       1
---------------------------------------------------------------------------
  516-  539 (41.29/28.55)	DEEFVLRFHDHSSLNSEDVLHVLG
  543-  566 (44.78/31.61)	DEELIISVRGEDSRRSRNSWWWLG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      87.04|      19|      22|     205|     223|       2
---------------------------------------------------------------------------
  205-  223 (35.66/24.48)	NRL..LDE......NCTEYSALCRMNM
  228-  248 (26.28/15.98)	NQLgnIDQ......EAVEYRTAGRLYI
  259-  281 (25.09/14.89)	NRL..SMEclymamHC..YSEAIRLHL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      83.61|      24|      25|     792|     815|       3
---------------------------------------------------------------------------
  792-  815 (42.33/30.94)	CCGLNEVQRIIQAQIVAEDMT.NQR
  820-  844 (41.28/29.98)	CMPLNYTMNVTSEQIFSMPCSlNQK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      64.65|      13|      68|     846|     858|       4
---------------------------------------------------------------------------
  846-  858 (24.77/14.72)	NNVLPNYVFRGSS
  916-  927 (23.28/13.40)	ENV.QNYCEKSWS
  938-  948 (16.60/ 7.49)	KTFLPTYCFIG..
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      46.61|      14|      21|     692|     705|       7
---------------------------------------------------------------------------
  692-  705 (24.88/15.01)	ILSAVSNTMHSY...NF
  712-  728 (21.72/12.18)	IISGIDEGIYGWitsNF
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      48.46|      15|      23|     595|     612|       9
---------------------------------------------------------------------------
  595-  609 (26.18/24.40)	GIIID.AGSSHSGLYI
  620-  635 (22.28/ 8.21)	GVIKQyAPSCSTEIGI
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP06252 with Med22 domain of Kingdom Metazoa
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