<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP06251

Description Ectonucleoside triphosphate diphosphohydrolase 1
SequenceMDEGRKNISARKAMLLKEYQVLLQRSVKSIRENFTEIIKMAKIGDDGQVSRLTEYEHELFEMQIRAANMTHAAEALIKMVTDLKQFLILNDFAYINESITTSAVHNQIAQREFRDKLIAVKEEMAYCLQEAEQEYYNTALKNSVSVLIHIFEIEFLRIKMTLDEFGTELYVDPWQTFVSIKGKLRKRAFRSPNLVEVVKDYEALANRLLDENCTEYSALCRMNMAKCKNQLGNIDQEAVEYRTAGRLYIRAEKEKESVENRLSMECLYMAMHCYSEAIRLHLSQGQKLLAASLLIELGKELACMQHPEDAIQNFERAVHLLDTHPHAVGHALRWKLCVETSVGFLADARRTSNFYRQIVESWPNSGSRKLHLNELEIITVMLLLALKPIKSEMNDFEKRLLQRYSDETDEALFTNDGSLLPNDSYIISVEIYLQLKSFVLAINNNDPSAADIALTAMHHHNVKLVHSTGSDASVPLRVLIKSLFYNESSVSLEVDSDFKVKDVINAYAYRTGRNEKDEEFVLRFHDHSSLNSEDVLHVLGVYNDEELIISVRGEDSRRSRNSWWWLGSVALLISLVGLIAVSVLFALSGDLPDEFGIIIDAGSSHSGLYIYTWNGRKNKTGVIKQYAPSCSTEIGISSFTDNPADAGNSLMFCLNNASATVPSKRHSATAMYLAATAGMRILELRDPLSSCKILSAVSNTMHSYNFLYKNASIISGIDEGIYGWITSNFLSHRLMNSASRLNDIRPLTFGAMDLGGASTQIIFEINTSEFTERNYSLRLFGETYNLFVDSYLCCGLNEVQRIIQAQIVAEDMTNQRPLHPCMPLNYTMNVTSEQIFSMPCSLNQKPNNVLPNYVFRGSSDPHSCLMKIRHMLDTSACSVKKAKIPKPRGEFMAFSGLYWAAKFFNCTSGCSYNKFFENVQNYCEKSWSYIEAAAYPYKKTFLPTYCFIGLYSLTLIKDAYHFSDAQIQDIKFVNEIDSTEIGWTLGFMLNATNQLPEEQPIEHIGLIEFSLITTICCIIRLEQLE
Length1025
PositionHead
OrganismTrichinella zimbabwensis
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Nematoda> Enoplea> Dorylaimia> Trichinellida> Trichinellidae> Trichinella.
Aromaticity0.10
Grand average of hydropathy-0.156
Instability index38.39
Isoelectric point5.76
Molecular weight116472.91
Publications









Function






Annotated function


GO - Cellular Component
integral component of membrane	GO:0016021	IEA:UniProtKB-KW
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
ATP binding	GO:0005524	IEA:UniProtKB-KW
hydrolase activity	GO:0016787	IEA:UniProtKB-KW
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP06251
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      74.43|      23|      26|     802|     826|       1
---------------------------------------------------------------------------
  802-  826 (35.98/36.65)	IIQAQIVAEDMT.NQRPlHPCMPlNY
  830-  853 (38.45/27.72)	VTSEQIFSMPCSlNQKP.NNVLP.NY
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      86.07|      24|      25|     517|     540|       2
---------------------------------------------------------------------------
  517-  540 (41.29/27.06)	DEEFVLRFHDHSSLNSEDVLHVLG
  544-  567 (44.78/29.99)	DEELIISVRGEDSRRSRNSWWWLG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      81.00|      24|      51|     362|     387|       3
---------------------------------------------------------------------------
  362-  387 (38.10/35.68)	WPNSGSrkLHLNELEIITVMLLLALK
  413-  436 (42.90/32.40)	FTNDGS..LLPNDSYIISVEIYLQLK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      38.28|      10|      25|     912|     923|       4
---------------------------------------------------------------------------
  912-  923 (16.97/16.96)	YNKFFenVQNYC
  937-  946 (21.31/13.13)	YKKTF..LPTYC
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     100.24|      19|      25|     204|     222|       5
---------------------------------------------------------------------------
  204-  222 (35.37/25.13)	LANRLLDE......NCTEYSALCRM
  231-  247 (26.14/16.51)	LGN..IDQ......EAVEYRTAGRL
  258-  280 (22.75/13.33)	VENRLSMEclymamHC..YSEAIRL
  289-  303 (15.99/ 7.01)	LAASLLIE......LGKELA..C..
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      46.61|      14|      22|     693|     706|       6
---------------------------------------------------------------------------
  693-  706 (24.88/14.76)	ILSAVSNTMHSY...NF
  713-  729 (21.72/11.99)	IISGIDEGIYGWitsNF
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      83.04|      25|     609|     150|     174|       7
---------------------------------------------------------------------------
  150-  174 (47.95/30.20)	IFEI...EFLRIKMTLDEFGT..ELYVDPW
  762-  791 (35.09/20.26)	IFEIntsEFTERNYSLRLFGEtyNLFVDSY
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      48.46|      15|      24|     596|     613|       8
---------------------------------------------------------------------------
  596-  610 (26.18/19.27)	GIIID.AGSSHSGLYI
  621-  636 (22.28/ 6.57)	GVIKQyAPSCSTEIGI
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP06251 with Med22 domain of Kingdom Metazoa
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