<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP06230

Description Mediator of RNA polymerase II transcription subunit 26 (Fragment)
SequenceLFKQMQALPVERLKVRLLSCLDREKKVNNVAKACEAMDAIESVVMTKESLESSRLGLLINEVRRSNQLLHPDLAKRCRLLIKKWRKLISTTPTPTPTPTTTTQPAITDNGVDTAGVAPVAADDRAIRIRIKLGSSVNEATILGGQEKKKQQQQQQLDNCGIEQAENRRKRKHTSQNAPNNSKMNGISKTHLSAIGGNGGGSGETFSLASTVSKPCKPPRSSSSCSRPVPLPTAPASQPRHPPPPQPPLPPPSAPTPPPPPPPPPPPQSSPPPLPPSPPPPTPPPPPPPSTSPSLTTTSSRPPKLKTTAQLVADLTKCYPEELLVNINTSIGVDSTNALQQATASNSGDDAPSPALLFSAVEHQQPSGGGGGEVNKLELLEKYLAEDADQQQQNQDHVVAGSSSGACTSSSSVDSDTSSRSSTPSRDKIVRASDDDDDDAPPRSGPGTVSSPSDGGGKPGLVDDGRRPIRRLPPVDRSMLDRLDEIPSPSKSRVSSLKYLDDYSNEPPERTRALAPFEQSLRMLPSEMRQLHSRVLVKTTDGRQVLALPYVDIGLPDFLEYDNSPATTEQLISWEAIRW
Length578
PositionUnknown
OrganismTrichinella britovi (Parasitic roundworm)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Nematoda> Enoplea> Dorylaimia> Trichinellida> Trichinellidae> Trichinella.
Aromaticity0.02
Grand average of hydropathy-0.696
Instability index73.01
Isoelectric point8.51
Molecular weight61943.94
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP06230
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     129.50|      20|      20|     246|     265|       1
---------------------------------------------------------------------------
  233-  252 (42.09/10.18)	APASQPRHPPPPQP.PLPPPS
  253-  273 (41.95/10.12)	APTPPPPPPPPPPPqSSPPPL
  274-  293 (45.46/11.57)	PPSPPPPTPPPPPP.PSTSPS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      99.00|      30|      85|     343|     374|       2
---------------------------------------------------------------------------
  343-  374 (48.94/29.58)	ASNSGDDAPSPALLFSAVehQQPSGGGG..GEVN
  431-  462 (50.06/24.76)	ASDDDDDDAPPRSGPGTV..SSPSDGGGkpGLVD
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     128.50|      32|      75|     463|     494|       5
---------------------------------------------------------------------------
  463-  494 (56.56/30.56)	DGRRPIRRLPPVDRSMLDRL..DEIPSPSKSRVS
  515-  534 (24.20/ 8.78)	PFEQSLRMLPSEMRQLHSRV..............
  540-  572 (47.73/24.62)	DGRQ.VLALPYVDIGLPDFLeyDNSPATTEQLIS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      48.37|      15|      17|     141|     155|       6
---------------------------------------------------------------------------
  141-  155 (24.34/17.11)	ILGGQEKKKQQQQQQ
  161-  175 (24.02/16.79)	IEQAENRRKRKHTSQ
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP06230 with Med26 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) NEATILGGQEKKKQQQQQQLDNCGIEQAENRRKRKHTSQNAPNNSKMNGISKTHLSAIGGNGGGSGETFSLASTVSKPCKPPRSSSSCSRPVPLPTAPASQPRHPPPPQPPLPPPSAPTPPPPPPPPPPPQSSPPPLPPSPPPPTPPPPPPPSTSPSLTTTSSRPPKLKTTAQLVADLTKCYPEELLVNINTSIGVDSTNALQQATASNSGDDAPSPALLFSAVEHQQPSGGGGGEVNKLELLEKYLAEDADQQQQNQDHVVAGSSSGACTSSSSVDSDTSSRSSTPSRDKIVRASDDDDDDAPPRSGPGTVSSPSDGGGKPGLVDDGRRPIRRLPPVDRSMLDRLDEIPS
2) SKSRVSSLKYLDDYSNEPPERTRALAPFEQSLRM
137
489
487
522










Molecular Recognition Features






MoRF SequenceStartStop




1) LLFSA
2) RLLIKKWRKLIS
3) VNKLELLEKYLAEDA
4) VSSLKYLDDYS
355
78
373
493
359
89
387
503