<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP06224

Description Ectonucleoside triphosphate diphosphohydrolase 1
SequenceMDEGRKNINARKAMLLKEYQVLLQRSVKSIRENFTEIIRMAKVGEEGQVSRLTEYEHELFEMQIRAANMTHAAEALIKMVTDLKQFLILNDFAYINESITTTAVHSQIAQREFRDKLIAVKEEMTFYLQEAEQEYYNTAINMTLDEFGTELYVDPWQTFVSIKGKLRKRAFRSPNLAEVVKDYDALASRLLDENCTEYSALCRMNMAKCKNQLGNTDQEAVEYRTAGRLYIRAEKEKESVENRLSMECLYMAMHCYNEAIRLHLSQGQKLLAASLLIELGKELACMQHPEDAIQNFEKAIHLLDTHPHAVGHALRWKLCVETSVGFLADARRTSNFYRQIVESWPNSGFRKLHLNELEIITVMLLLALKPIKSEMNDFEKRVLQRYSDETDEALLSSYEGSLLPNDSYIISVEIYLHLKSFVLAINNNDPSAADIALTAIHHRNVKLVHSAGADASLPLRVFIKSLLYNESSVSLEVDSDFKVRDVINAYAYRTGHSEKDEEFVLRFHDHSSLNSEDVLHVLGIYNDEELIISVRGEDSRRSRNSWWWLGSVALLISLVGLTAVSVLFALSGDLPDEFGIIIDAGSSHSGLYIYTWNGRKNKTGVIKQYAPSCSTEDGISSFTDNPTDAGNSLIFCLNNASATVPSKRHSSTAMYLAATAGMRILEIRDPLSSCKITNAVSNTMHSYNFLFKNASIISGIDEGIYGWITLNFLSHRLMNSASKLNDIRPLTIGAMDLGGASTQIIFEINSSEFTERNYSLKLFGETYNLFVDSYLCCGANEVQRIIQAQIVAEDTTNQQPLHPCLPLNYTMNVTSEQIFLMPCSLNQKPNNVLPNYVFRGSSDPHSCLKKIRYMLDTSACSVKKAKIPKPRGEFMAFSGMYWTAKFFNCTSGCSYNKFFENVQNYCEKSWSSIEAAAYPYKKTFLSTYCFTGLYSLTLFKDAYRFSDAQIQKIEFVNEIDSTEIGWTLGFMLNATNQLPEEQPIEHIGLIEFSLITTICCISGEGG
Length1006
PositionHead
OrganismTrichinella britovi (Parasitic roundworm)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Nematoda> Enoplea> Dorylaimia> Trichinellida> Trichinellidae> Trichinella.
Aromaticity0.10
Grand average of hydropathy-0.192
Instability index35.04
Isoelectric point5.66
Molecular weight113895.46
Publications









Function






Annotated function


GO - Cellular Component
integral component of membrane	GO:0016021	IEA:UniProtKB-KW
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
ATP binding	GO:0005524	IEA:UniProtKB-KW
hydrolase activity	GO:0016787	IEA:UniProtKB-KW
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP06224
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      67.03|      19|      22|     217|     238|       1
---------------------------------------------------------------------------
  192-  210 (35.78/20.63)	DENCTEYSALCRMNMAKCK
  217-  235 (31.25/25.73)	DQEAVEYRTAGRLYIRAEK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      40.83|      10|      21|     795|     813|       2
---------------------------------------------------------------------------
  795-  804 (21.77/15.59)	TTNQQPLHPC
  814-  823 (19.06/15.05)	TSEQIFLMPC
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      43.30|      15|      21|     468|     484|       3
---------------------------------------------------------------------------
  468-  484 (16.45/19.22)	YNESSvSlEVDSDFKVR
  492-  506 (26.85/17.85)	YRTGH.S.EKDEEFVLR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     188.44|      58|     253|     671|     733|       5
---------------------------------------------------------------------------
  671-  733 (94.00/79.39)	LSSCKITNAVSNTMHSYNFLFKNASI.....ISGIDEGIYGWiTLNFlshrLMNSASKLNDIRPLT.IG
  925-  988 (94.43/64.93)	LSTYCFTGLYSLTLFKDAYRFSDAQIqkiefVNEIDSTEIGW.TLGF....MLNATNQLPEEQPIEhIG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     100.84|      31|     198|      72|     136|       6
---------------------------------------------------------------------------
   89-  119 (51.14/84.37)	LNDFA...YINESITTTAVHSQIAQREFRDKLIA
  144-  177 (49.70/15.43)	LDEFGtelYVDPWQTFVSIKGKLRKRAFRSPNLA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      42.95|      11|     138|     851|     862|      10
---------------------------------------------------------------------------
  851-  861 (20.71/16.58)	IRYMLDTSACS
  884-  894 (22.23/11.53)	AKFFNCTSGCS
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP06224 with Med22 domain of Kingdom Metazoa
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