<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP06223

Description Ectonucleoside triphosphate diphosphohydrolase 1
SequenceMDEGRKNINARKAMLLKEYQVLLQRSVKSIRENFTEIIRMAKVGEEGQVSRLTEYEHELFEMQIRAANMTHAAEALIKMVTDLKQFLILNDFAYINESITTTAVHSQIAQREFRDKLIAVKEEMTFYLQEAEQEYYNTALKNSVSVLDLFEIECLRINMTLDEFGTELYVDPWQTFVSIKGKLRKRAFRSPNLAEVVKDYDALASRLLDENCTEYSALCRMNMAKCKNQLGNTDQEAVEYRTAGRLYIRAEKEKESVENRLSMECLYMAMHCYNEAIRLHLSQGQKLLAASLLIELGKELACMQHPEDAIQNFEKAIHLLDTHPHAVGHALRWKLCVETSVGFLADARRTSNFYRQIVESWPNSGFRKLHLNELEIITVMLLLALKPIKSEMNDFEKRVLQRYSDETDEALLSSYEGSLLPNDSYIISVEIYLHLKSFVLAINNNDPSAADIALTAIHHRNVKLVHSAGADASLPLRVFIKSLLYNESSVSLEVDSDFKVRDVINAYAYRTGHSEKDEEFVLRFHDHSSLNSEDVLHVLGIYNDEELIISVRGEDSRRSRNSWWWLGSVALLISLVGLTAVSVLFALSGDLPDEFGIIIDAGSSHSGLYIYTWNGRKNKTGVIKQYAPSCSTEDGISSFTDNPTDAGNSLIFCLNNASATVPSKRHSSTAMYLAATAGMRILEIRDPLSSCKITNAVSNTMHSYNFLFKNASIISGIDEGIYGWITLNFLSHRLMNSASKLNDIRPLTIGAMDLGGASTQIIFEINSSEFTERNYSLKLFGETYNLFVDSYLCCGANEVQRIIQAQIVAEDTTNQQPLHPCLPLNYTMNVTSEQIFLMPCSLNQKPNNVLPNYVFRGSSDPHSCLKKIRYMLDTSACSVKKAKIPKPRGEFMAFSGMYWTAKFFNCTSGCSYNKFFENVQNYCEKSWSSIEAAAYPYKKTFLSTYCFTGLYSLTLFKDAYRFSDAQIQKIEFVNEIDSTEIGWTLGFMLNATNQLPEEQPIEHIGLIEFSLITTICCISGEGG
Length1023
PositionHead
OrganismTrichinella britovi (Parasitic roundworm)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Nematoda> Enoplea> Dorylaimia> Trichinellida> Trichinellidae> Trichinella.
Aromaticity0.10
Grand average of hydropathy-0.180
Instability index35.96
Isoelectric point5.63
Molecular weight115855.76
Publications









Function






Annotated function


GO - Cellular Component
integral component of membrane	GO:0016021	IEA:UniProtKB-KW
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
ATP binding	GO:0005524	IEA:UniProtKB-KW
hydrolase activity	GO:0016787	IEA:UniProtKB-KW
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP06223
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      94.39|      30|      51|     873|     903|       1
---------------------------------------------------------------------------
  873-  903 (53.47/35.68)	DTSACSVKK..................AKIPKPRgEFMA...FSGMYWTAKF
  906-  956 (40.92/22.11)	CTSGCSYNKffenvqnycekswssieaAAYPYKK.TFLStycFTGLYSLTLF
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      96.57|      25|      51|     634|     658|       2
---------------------------------------------------------------------------
  606-  630 (20.03/ 7.56)	SGLYI..YTWNGRKNKTGVIkqyapSC.....
  634-  658 (43.20/24.16)	DGISS..FTDNPTDAGNSLI.....FCLNNAS
  686-  712 (33.33/17.09)	DPLSSckITNAVSNTMHSYN.....FLFKNAS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      43.32|      16|      18|     820|     836|       3
---------------------------------------------------------------------------
  827-  844 (24.98/13.39)	TMNVTSEQIF.....lmPC..SLNQ
  846-  870 (18.34/ 9.77)	PNNVLPNYVFrgssdphSClkKIRY
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      67.03|      19|      22|     234|     255|       5
---------------------------------------------------------------------------
  209-  227 (35.78/21.72)	DENCTEYSALCRMNMAKCK
  234-  252 (31.25/27.10)	DQEAVEYRTAGRLYIRAEK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      43.30|      15|      21|     485|     501|       6
---------------------------------------------------------------------------
  485-  501 (16.45/18.13)	YNESSvSlEVDSDFKVR
  509-  523 (26.85/16.85)	YRTGH.S.EKDEEFVLR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      84.86|      27|     174|      96|     148|      10
---------------------------------------------------------------------------
   96-  122 (42.93/57.70)	NESITTTAVHSQIAQREFRDKLIA..VKE
  171-  199 (41.93/12.94)	DPWQTFVSIKGKLRKRAFRSPNLAevVKD
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP06223 with Med22 domain of Kingdom Metazoa
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