<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP06209

Description Mediator of RNA polymerase II transcription subunit 24
SequenceMEESSMNAVEQLLFDAWSECWPDIIFMKQLRQRIEITNQNIEQLSSLLLYYVTLSEMPNRLMLKYIRFCLDTQVVPCVAFLNVVNSYRCYEKVGCINEILVLVIYCLDKLNCDFCDADVCVRTSILVMNTVLWILAYVEYLLTSNNFPPSAHLWSLVFTLKENKFVQFCNYFVCWELSEFHDQIQVSIVNIKVKIEENRHSFPADLLDNMLTFLSFFDIEKNSYDNLFSANPNEILAKSVRASDSRIPSVVISLSGIFAHVQSMKGIAAMVEALKVAKDIQGESWLNILYDLIMGGILQQHDDSTTLPFSVSSSYLYLRIPRLLSQLVAEGIPKETLIGSLRRIATSEAVLNVSDTKARCNTLQAFLNVLSELGILEESEKDTLMAIRDEMRKELYVQEGQPTINLVLRAEFTLQSIVKAFDAHQALERWPQMLNTMMSGKSLLYICAAAISIDQLNLLAERLIKITETYKEVVPVGEDAQKSVPPSHDLFDMSFLLLHRLSQYYSTTTCLRPGDPFFKTWYFSSAIDLVRNMFDPEDLPQLLKNVPLDLELATDVLSRLRVGQPGWLNIRTWYCIIDLIPSIVQVVLNEVLLDTISIEELKHIFSGLLFLNIHGVSCMCSPLLCFAQYVALQKTDEATKLASSLFSFFESITPSDAERNRQTDRQTFMVNSAKKLFSTYRELPVTLMHVLRMNRAPAQLNHSPDDHFPVIGKPENIRSFFAASERAGYLTAALIARIIVLVESEQYDSWLSAFIEALQKVNTMQGMEKWCNLNLACCFIRPKECTLALIPLLSNYVLHDDRDLFCVAPRGNILAFFLVKLYLIALRYTTPTAVEKAETTEFSVDECSVQNNTNSSTADRSAVITSLRELFSCKFEVVRSGELCPTVAFVSNFLYCLSEYSTPEAELIKNEIPMHLIFSLLRADPDILSMRTVLRLFDLKGEIQRRKALQIAFLLKRKKHL
Length961
PositionTail
OrganismTrichinella britovi (Parasitic roundworm)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Nematoda> Enoplea> Dorylaimia> Trichinellida> Trichinellidae> Trichinella.
Aromaticity0.10
Grand average of hydropathy0.141
Instability index46.85
Isoelectric point5.40
Molecular weight109608.09
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP06209
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     253.46|      77|     151|     519|     604|       1
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  205-  299 (38.38/15.35)	DLLDNMltflsfFDIEknSYDNLFSANPNEI.LAKSVrasdsripsvvislsgifahvqsmkgiaamVEALK..................VAKdiqgESWLNI..L........Y...DLImGGILQ.....................
  528-  604 (132.93/106.85)	DLVRNM......FDPE..DLPQLLKNVPLDLELATDV..............................LSRLR..................VGQ....PGWLNIRTW........YCIIDLI.PSIVQVVLNEVLLDTIS..IEELKHI
  665-  761 (82.14/51.60)	...RQT......FMVN..SAKKLFSTYR...ELPVTL..............................MHVLRmnrapaqlnhspddhfpvIGK....P..ENIRSFfaaseragYLTAALI.ARIIVLVESEQYDSWLSafIEALQKV
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     235.67|      75|     331|     435|     524|       8
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  435-  524 (111.68/135.98)	NTMmsgKSLLYICaaaisidQLNlLAERLIKITETYKEVVP.....VGEDAQK..SVPPSHDLFDMSFLLLHRLSQYYSTTTCLRPGDpffkTWYFS
  762-  843 (123.98/102.08)	NTM...QGMEKWC.......NLN.LACCFIRPKECTLALIPllsnyVLHDDRDlfCVAPRGNILAFFLVKLYLIALRYTTPTAVEKAE....TTEFS
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      82.06|      25|      52|     100|     124|       9
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  100-  124 (46.37/23.21)	LVLVIYCLDKLNCD......................FCDADVCVRTS
  132-  178 (35.69/16.50)	LWILAYVEYLLTSNnfppsahlwslvftlkenkfvqFCNYFVCWELS
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP06209 with Med24 domain of Kingdom Metazoa
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