<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP06196

Description Mediator of RNA polymerase II transcription subunit 24
SequenceMLFSNYSQQHEVTGQQLYFGHWARSTTTTRITVVHFPKTKLNHSLYSHLGLGLASERNVRKMIHDSYMDYMIQQNQPQKNRLKEKLLYFSSMMIPQLHHFQFPDTLMAIRDEMRKELYIQEGQPTINLVLRAEFTLQSIVKAFDAHQALERWPQMLNTMMSGKSLLYICAAAISIDQLNLLAERLIKITETYKEVVPVGEDAQKSVPPSHDLFDMSFLLLHRLSQYYSTTTCLRPGDPFFKTWYFSSAIDLVRNMFDPEDLPQLLKNVPLDLELASDVLSRLRVGQPGWLNIRTWYCIIDLIPSIVQVVLNEVLLDTISIEELKVCKQSL
Length330
PositionTail
OrganismTrichinella spiralis (Trichina worm)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Nematoda> Enoplea> Dorylaimia> Trichinellida> Trichinellidae> Trichinella.
Aromaticity0.10
Grand average of hydropathy-0.132
Instability index43.37
Isoelectric point6.60
Molecular weight38329.03
Publications

Function

Annotated function
GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro
GO - Biological Function
GO - Biological Process

Interaction

Binary Interactions

Repeat regions

Repeats

>MDP06196
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     116.34|      41|      48|      72|     119|       1
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    8-   77 (48.64/35.68)	QQHEVTGQQLYFGhwarSTTTTRITVVHFP......KTKLNHSLyshlglglasernvrkmihdsymdYMIQqNQP
   78-  124 (67.70/58.86)	QKNRLKEKLLYFS....SMMIPQLHHFQFPdtlmaiRDEMRKEL........................YIQE.GQP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      66.90|      18|      49|     233|     252|       2
---------------------------------------------------------------------------
  233-  252 (32.58/27.78)	LRPGDPFF...KTWYfsSAIDLV
  282-  302 (34.32/21.94)	LRVGQPGWlniRTWY..CIIDLI
---------------------------------------------------------------------------




Explaination for Stockholm format The "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space.

#=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00)

#=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column. It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column. This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.

#=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.

Alignment of MDP06196 with Med24 domain of Kingdom Metazoa

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