<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP06181

Description Mediator of RNA polymerase II transcription subunit 23 (Fragment)
SequenceMSVSLSDFEAKVKNLFKEHAKSGNAHFFFRPYLITSSEECEKEIVISTANELMEIFTSLPQNLQESAFSIVISHRVLSNSANRIVDFFVRNVTQRQMLSIKCICEKLLTCAELNINSCGWNDTFAFFVENISLLDYKDLLNPQMRLLTHVFMHYTYRDAIAVLLGTAKPEKSRIPYFEEVITEIILELMFTAECDHSQLNPQAWRIISTQIIYLTLQQSICFTRLVKILHTKLTHYPYRYARNQLMWCLFNFLSGGMQKYSGKSAWPSPALVETYCRMLTYPDLEILGLKQFTSHIVLTAARHQCCEMMYICCEILNYRLFNIPSTYRVHAIVTLQQTLAFAKFQTNASLYWMYRYYYYYYYFAPFARLLNSFVAVAADGTKQSIAENEELMRIIILTLARSTVISSKVLGPRKVLVHLKSLADFLVYETNSADVNRCVDVLNRLIFKYAVVPLERFMLTMLLRDYEGNDAFYALLIVMLLVQRSEELRSAVADCVAMLPSDYWHCQDWNDKYQAYQIKHAERTWSQVYVELSRASLTPNDCPLPVYFGTRCLQMLPVVDLLLQKLVESPAACLKFLDSTLSILGPLYRFHPYPVSFLYSTFRFYEKRLVESPAIKQKLALAVHGACVPSRDDHWLLSAEFVGWVGQATDRGPWVPDLNYYGALVRRLIDTFSEPRQQWSRKTDLRFVEFNNFQTHALYSICIELMSLPVGVVDVGNALVTLVTHWHSLVDKNTVMYWVNAIGLIFSALPISYMEPFYQTILTTLCSDHMNSINTDVSNKLDFEKRSKLMEDCYPARILALCHAVWLHSASGYLQLLPQALRSTWIPHVRSEGQFLYVCHLVAPFLQRFYQERTKFTMDITTDLYQMLYNVDCEVGNWKYEDLICDFFYHVKYMYVGDSVRQDTDRIIPMLRPSLQQKLRYISFAQGEQSAGTPFSEMINPIKLLGIQMVVWLQRLPIFGETAQHFWLAVTKLGDPLCFHFLAPLRWIWILLDDRPYWWVHTAGVSGQLSHPLKQFQWTCETGPGSPSGHAMVSASVWFNLLYNLQSDLVLGDLCGICWLLYVVFLIAVSISRTYISAHFPDQVILGIVVGICMALVTRSLVGHRRRRWSNLIAFMIALLLIALSVHEAHRFFGVDTHRSIELAAKYCHRAEWIHQSTTPLASFFRDVGVLISVAILLANKSMFTNNNKIASKFFSTKFAQALLGVGLNQLVALIPIGRLPTALFYAVLLPVLFTNNSNKLQ
Length1242
PositionTail
OrganismTrichinella patagoniensis
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Nematoda> Enoplea> Dorylaimia> Trichinellida> Trichinellidae> Trichinella.
Aromaticity0.13
Grand average of hydropathy0.169
Instability index42.76
Isoelectric point8.28
Molecular weight143090.04
Publications









Function






Annotated function


GO - Cellular Component
integral component of membrane	GO:0016021	IEA:UniProtKB-KW
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP06181
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      95.85|      29|      34|     786|     819|       1
---------------------------------------------------------------------------
  786-  819 (44.83/35.64)	RSKLMEDCYP.ARILALCHAVwlhsaSGYLQLLPQ
  822-  851 (51.03/27.67)	RSTWIPHVRSeGQFLYVCHLV.....APFLQRFYQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     159.35|      37|      40|     535|     571|       2
---------------------------------------------------------------------------
  466-  507 (25.57/ 9.15)	..Y.EGND..AFYAL.LIVMLLVQRseeLRSAVAdcVAMLPSDywhCQ.
  508-  544 (45.42/21.05)	..D.WNDKyqAYQIK.HAERTWSQV...YVELSR..ASLTPND...CPL
  545-  581 (60.55/30.13)	PVY.FGTR..CLQML.PVVDLLLQK...LVESPA..ACLKFLD...STL
  586-  614 (27.81/10.50)	PLYrFHPY..PVSFLySTFRFYEKR...LVESPA...............
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     103.14|      29|      31|     958|     987|       3
---------------------------------------------------------------------------
  958-  987 (49.39/38.38)	IFGETAQHFWLAVTKLGDPLCfHFLAPLRW
  990- 1018 (53.74/36.37)	ILLDDRPYWWVHTAGVSGQLS.HPLKQFQW
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      74.97|      26|      31|      49|      77|       4
---------------------------------------------------------------------------
   49-   77 (38.53/32.36)	ANELMEIFTslpQNL.QESAFSI.VISHRVL
   81-  108 (36.44/21.84)	ANRIVDFFV...RNVtQRQMLSIkCICEKLL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      67.48|      18|      31|     196|     213|       5
---------------------------------------------------------------------------
  196-  213 (32.36/16.42)	HSQLNPQAWRIISTQIIY
  230-  247 (35.12/18.35)	HTKLTHYPYRYARNQLMW
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      63.20|      19|      31|     657|     675|       6
---------------------------------------------------------------------------
  657-  675 (33.48/25.30)	DLNYYG..ALVRRLIDTFSEP
  689-  709 (29.73/21.46)	EFNNFQthALYSICIELMSLP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      48.71|      14|     252|     641|     656|       7
---------------------------------------------------------------------------
  641-  656 (25.83/22.89)	FVG.WVGQATDRgpWVP
  895-  909 (22.88/12.32)	YVGdSVRQDTDR..IIP
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP06181 with Med23 domain of Kingdom Metazoa
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