<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP06180

Description Mediator of RNA polymerase II transcription subunit 23 (Fragment)
SequenceMSVSLSDFEAKVKNLFKEHAKSGNAHFFFRPYLITSSEECEKEIVISTANELMEIFTSLPQNLQESAFSIVISHRVLSNSANRIVDFFVRNVTQRQMLSIKCICEKLLTCAELNINSCGWNDTFAFFVENISLLDYKGVRDTLKRLLDIPIPVHLQVDQRKSVEAVEKLIKTICDRKNNLLPAYFVITEIIKNLPEQRCFSHWRMADCFTEIIESFRPLAQLNSVCGRTFMTPIPGHVGFYFNAFWKLEALSLRFPLKGLLPYSQDLLNPQMRLLTHVFMHYTYRDAIAVLLGTAKPEKSRIPYFEEVITEIILELMFTAECDHSQLNPQAWRIISTQIIYLTLQQSICFTRLVKILHTKLTHYPYRYARNQLMWCLFNFLSGGMQKYSVEEFAVILDLYRLLYTGRDIFTVSGSDSSCVLMLAPTCIWIHILKKSPSMEVELPPTVNTQRKFLQEALKNKTQFNTDNYMVAVLCNAYSSTSEIFQQDLLPILLENLDNTRGHNSTQASGNFASNATSSMPYPNGAVSEVKLRPLKLEFLDSVSVHVRMNIANSLIGTFGRFMQGKSAWPSPALVETYCRMLTYPDLEILGLKQFTSHIVLTAARHQCCEMMYICCEILNYRLFNIPSTYRVHAIVTLQQTLAFAKFQTNASLYWMLERTLLLQFQWYPHYEIFQAPFARLLNSFVAVAADGTKQSIAENEELMRIIILTLARSTVISSNSDSCFIEGVYRELLNKLPSYSWPQSTLSVFPQVFCSHYTQQQQQQQQQQQQQQQQQQQQPQQPQQQQQQQQQPQPQQSNVVVGSSQQPQQQQQSRFLLKQQVDEEYIKHRTFGSELSLIDYFTNTSTSTVYLCLLWRLVYDTGELPAVSMKILEVLGPRKVLVHLKSLADFLVYETNSADVNRCVDVLNRLIFKYAVVPLERFMLTMLLRDYEGNDAFYALLIVMLLVQRSEELRSAVADCVAMLPSDYWHCQDWNDKYQAYQIKHAERTWSQVYVELSRASLTPNDCPLPVYFGTRCLQMLPVVDLLLQKLVESPAACLKFLDSTLSILGPLYRFHPYPVSFLYSTFRFYEKRLVESPAIKQKLALAVHGACVPSRDDHWLLSAEFVGWVGQATDRGPWVPDLNYYGALVRRLIDTFSEPRQQWSRKTDLRFVEFNNFQTHALYSICIELMSLPVGVVDVGNALVTLVTHWYSNSNSSQSSRHSLVDKNTVMYWVNAIGLIFSALPISYMEPFYQTILTTLCSDHMNSINTDVSNKLDFEKRSKLMEDCYPARILALCHAVWLHSASGYLQLLPQALRSTWIPHVRSEGQFLYVCHLVAPFLQRFYQERTKFTMDITTDLYQMLYNVDCEVGNWKYEDLICDFFYHVKYMYVGDSVRQDTDRIIPMLRPSLQQKLRYISFAQGEQSAGTPFSEMINPIKLLGIQMVVWLQRLPIFGETAQHFWLAVTKLGDPVMTFSLYFPALFPFFGTAALDMVIVGAFSEISNCILKWILLDDRPYWWVHTAGVSGQLSHPLKQFQWTCETGPGSPSGHAMVSASVWFNLLYNLQSDLVLGDLCGICWLLYVVFLIAVSISRTYISAHFPDQVILGIVVGICMALVTRSLVGHRRRRWSNLIAFMIALLLIALSVHEAHRFFGVDTHRSIELAAKYCHRAEWIHQSTTPLASFFRDVGVLISVAILLANKSMFTNNNKIASKFFSTKFAQALLGVGLNQLVALIPIGRLPTALFYAVLLPVLFTNNSNKLQ
Length1744
PositionTail
OrganismTrichinella patagoniensis
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Nematoda> Enoplea> Dorylaimia> Trichinellida> Trichinellidae> Trichinella.
Aromaticity0.12
Grand average of hydropathy0.042
Instability index47.56
Isoelectric point7.85
Molecular weight200212.50
Publications









Function






Annotated function


GO - Cellular Component
integral component of membrane	GO:0016021	IEA:UniProtKB-KW
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP06180
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     104.81|      19|      19|     760|     778|       1
---------------------------------------------------------------------------
  760-  778 (40.25/21.82)	QQQQQQQQQQQQQQQQQQQ
  779-  797 (40.73/22.16)	QPQQPQQQQQQQQQPQPQQ
  806-  821 (23.83/10.18)	QQPQQQQQSRFLLKQQ...
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     155.41|      47|      80|     918|     967|       2
---------------------------------------------------------------------------
  918-  967 (77.00/49.44)	VPLERFMLT...MLLRDYEGNDAFYALLIVMLLVQRseeLRSAVADCVAMLPS
  996- 1045 (78.41/43.84)	VELSRASLTpndCPLPVYFGTRCLQMLPVVDLLLQK...LVESPAACLKFLDS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     157.95|      50|      81|    1574|    1626|       3
---------------------------------------------------------------------------
 1574- 1626 (82.13/63.40)	SRTYISAHFPDqviLGIVVGICMALVTRSLVGHRRRRWSNLIA..FMIALLLIAL
 1659- 1710 (75.82/50.50)	STTPLASFFRD...VGVLISVAILLANKSMFTNNNKIASKFFStkFAQALLGVGL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     157.68|      38|      84|     112|     154|       4
---------------------------------------------------------------------------
   79-  110 (45.79/23.78)	NSA....NRIVDFFVRNVTQRQMLSIKCICEKLLTC.....
  116-  154 (63.00/52.62)	NSCgW..NDTFAFFVENISLLDYKGVRDTLKRLLDIPIPVH
  203-  237 (48.89/29.13)	....WrmADCFTEIIE..SFRPLAQLNSVCGRTFMTPIPGH
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      57.72|      15|      84|     273|     287|       5
---------------------------------------------------------------------------
  273-  287 (28.85/17.32)	RLLTHVFMHYTYRDA
  355-  369 (28.86/17.33)	KILHTKLTHYPYRYA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     385.23|      95|     306|    1059|    1173|       6
---------------------------------------------------------------------------
 1059- 1153 (163.11/106.50)	YPVSFLY..STFRFYEKRLVE......SPAIKQKLALAVHGA....CVPSR.....DDHW........LLSAEFVGWVGQ.....ATDRGPWV................PDL.NYYG..ALVRRLIDTFSEPRQ...QWSRKTDLRF
 1226- 1333 (133.39/83.68)	LPISYME..PFYQTILTTLCSdhmnsiNTDVSNKLDFEKRSKlmedCYPARilalcHAVW........LHSASGYLQLLP.....QALRSTWI................PHV.RSEG..QFL..YVCHLVAPFL...QRFYQERTKF
 1366- 1491 (88.73/68.63)	YHVKYMYvgDSVRQDTDRIIP....mlRPSLQQKLRYISFAQ....GEQSA.....GTPFseminpikLLGIQMVVWLQRlpifgETAQHFWLavtklgdpvmtfslyfPALfPFFGtaALDMVIVGAFSEISNcilKW........
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     101.35|      34|      40|     456|     495|       7
---------------------------------------------------------------------------
  458-  495 (54.94/42.18)	LKNKTQFN....TDNYMvavlCNAYSS....TSEIFQQDLLPILLE
  497-  538 (46.41/22.38)	LDNTRGHNstqaSGNFA....SNATSSmpypNGAVSEVKLRPLKLE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     193.10|      46|      85|     545|     590|       8
---------------------------------------------------------------------------
  545-  590 (79.90/53.20)	VHVRMNIANSLIGTFGRFMQGKS.AWPSPALVETYCRMLT.YPDLEIL
  592-  626 (53.68/33.02)	LK...QFTSHIVLTAARH........QCCEMMYICCEILN.YRLFNI.
  632-  674 (59.52/37.52)	VHAIVTLQQTL..AFAKFQTNASlYW...MLERTLLLQFQwYPHYEIF
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP06180 with Med23 domain of Kingdom Metazoa
Unable to open file!