<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP06172

Description Mediator of RNA polymerase II transcription subunit 26 (Fragment)
SequenceLKHGDSVQANASVAGGAFKGSPVKLLGQREEGTLKFVNNVAKACEAMDAIESVVMTKESLESSRLGLLINEVRRSNQLLHPDLAKRCRLLIKKWRKLISTTPTPTPTPTTTTQPAITDNGVDTAGVAPVAADDRAIRIRIKLGSSVNEATILGGQEKKQQQQQQQQLDNCGIEQAENRRKRKHTSQNAPNNSKMNGISKTHHSAIGGNGGGSGETFSLTSTVSKPCKPPRSSSSCSRPVPLPTAPASQPRHPPPPQPPLPPPSAPTPPPPPPPPPPPQSSPPPLPPSPPPPTPPPPPPPSTSPSLTTTSSRPPKLKTTAQLVADLTKCYPEELLVNINTSIGVDSTNALQQATASNSGDDAPSPALLFSAVEHQQPSGGGGGEVNKLELLEKYLAEDADQQQQNQDHVVAGSSSGACTSSSSVDSDTSSRSSTPSRDKIVRASDDDDDDAPPRSGPGTVSSPSDGGGKPGLVDDGRRPIRRLPPVDRSMLDRLDEIPSPSKSRVSSLKYLDDYSNEPPERTRALAPFEQSLRMLPSEMRQLHSRVLVKTTDGRQVLALPYVDIGLPDFLEYDNSPATTEQLISWEAIRW
Length589
PositionUnknown
OrganismTrichinella patagoniensis
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Nematoda> Enoplea> Dorylaimia> Trichinellida> Trichinellidae> Trichinella.
Aromaticity0.03
Grand average of hydropathy-0.708
Instability index72.31
Isoelectric point7.73
Molecular weight62681.35
Publications









Function






Annotated function


GO - Cellular Component
nucleus	GO:0005634	IEA:InterPro

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP06172
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     128.67|      20|      20|     257|     276|       1
---------------------------------------------------------------------------
  243-  262 (39.80/ 9.46)	TAPASQPRHPPPPQP.PLPPP
  263-  283 (43.85/11.14)	SAPTPPPPPPPPPPPqSSPPP
  284-  303 (45.02/11.63)	LPPSPPPPTPPPPPP.PSTSP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     100.63|      30|      85|     354|     385|       2
---------------------------------------------------------------------------
  354-  385 (50.17/25.83)	ASNSGDDAPSPALLFSAVehQQPSGGGG..GEVN
  442-  473 (50.46/21.26)	ASDDDDDDAPPRSGPGTV..SSPSDGGGkpGLVD
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     128.50|      32|      75|     474|     505|       5
---------------------------------------------------------------------------
  474-  505 (56.56/29.11)	DGRRPIRRLPPVDRSMLDRL..DEIPSPSKSRVS
  526-  545 (24.20/ 8.49)	PFEQSLRMLPSEMRQLHSRV..............
  551-  583 (47.73/23.48)	DGRQ.VLALPYVDIGLPDFLeyDNSPATTEQLIS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      48.25|      14|      17|     103|     116|       6
---------------------------------------------------------------------------
  103-  116 (25.72/12.67)	TPTPTPTTTTQPAI
  123-  136 (22.53/10.16)	TAGVAPVAADDRAI
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP06172 with Med26 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) ISTTPTPTPTPTTTTQPAITDNGVDTAGVAP
2) NEATILGGQEKKQQQQQQQQLDNCGIEQAENRRKRKHTSQNAPNNSKMNGISKTHHSAIGGNGGGSGETFSLTSTVSKPCKPPRSSSSCSRPVPLPTAPASQPRHPPPPQPPLPPPSAPTPPPPPPPPPPPQSSPPPLPPSPPPPTPPPPPPPSTSPSLTTTSSRPPKLKTTAQLVADLTKCYPEELLVNINTSIGVDSTNALQQATASNSGDDAPSPALLFSAVEHQQPSGGGGGEVNKLELLEKYLAEDADQQQQNQDHVVAGSSSGACTSSSSVDSDTSSRSSTPSRDKIVRASDDDDDDAPPRSGPGTVSSPSDGGGKPGLVDDGRRPIRRLPPVDRSMLDRLDEIPS
3) SKSRVSSLKYLDDYSNEPPERTRALAPFEQSLRM
98
147
500
128
498
533










Molecular Recognition Features






MoRF SequenceStartStop




1) CRLLIKKWRKLIST
2) LLFSAV
3) RVSSLKYLDDYS
4) VNKLELLEKYLAEDA
87
366
503
384
100
371
514
398