<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP06170

Description Forkhead box protein A2-A
SequenceMLLHSDYGHHHSGASDPNSALTYGTSTLGQAAAAAAVAGYSVQAHPSAGIGSYANLSANMNASALNNPYSNMPSFTGMNSMGGHHTLNGYGSMPSMASTMSSLTMGPSAMGSSALSPIGRTQMQVGASTNVTPNNSSVVMGNSSTSLARGGNAKNTYRRSYTHAKPPYSYISLITMAIQQSNSKMLTLSEIYQFIMDLFPYYRQNQQRWQNSIRHSLSFNDCFVKVPRTPDKPGKGSFWTLHPDCGNMFENGCYLRRQKRFKCEKRSGIAGSGGKGSRNASMSESGTFQAMVKVEEELEELQHHIQQQRSGQLNEASRGSPCEGTDSMQNHGIDLLTDERKIQSQDCAGNMLLISGDDDQQQQQQQQQQQQQQQQQQQQQQQQKQQQQQQQHVSSALIAGSPSSHGNMLNANDMAGPSADTRHSTPNTLVTTTDGGALDVNLLQQAMAENNSPNSAGASCSSPRDSLVGVGSSSLANEGLAPVISYGASPNSLPQSAVYSSFGQLPPNYTHDPFGTLAFTHPFSITNLIDSSKPDSTYNLPNCYGNGSSTAAAQLSYNSLSPMMSQIGQSSAMSDSMPYYHTLYSSNNPGSAANL
Length595
PositionTail
OrganismTrichinella patagoniensis
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Nematoda> Enoplea> Dorylaimia> Trichinellida> Trichinellidae> Trichinella.
Aromaticity0.06
Grand average of hydropathy-0.629
Instability index52.57
Isoelectric point6.54
Molecular weight63713.40
Publications









Function






Annotated function


GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
DNA-binding transcription factor activity	GO:0003700	IEA:InterPro
protein domain specific binding	GO:0019904	IEA:InterPro
sequence-specific DNA binding	GO:0043565	IEA:InterPro
transcription factor binding	GO:0008134	IEA:InterPro

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP06170
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      63.69|      15|      15|     360|     374|       1
---------------------------------------------------------------------------
  360-  374 (31.99/16.01)	QQQQQQQQQQQQQQQ
  376-  390 (31.70/15.82)	QQQQQQQQKQQQQQQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     206.23|      49|      49|     236|     284|       2
---------------------------------------------------------------------------
  197-  234 (44.78/20.11)	...........DLF...PYYRQnQQRWQNSIRHSLSFNDCfvKVPRTPDKPG
  236-  284 (87.70/45.52)	GSFWTLHPDCGNMFENGCYLRR.QKRFKCEKRSGIAGSGG..KGSRNASMSE
  286-  330 (73.74/37.26)	GTFQAMVKVEEELEELQHHIQQ.QRSGQLNEAS..RGSPC..EGT..DSMQN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     187.67|      36|      48|      39|      78|       3
---------------------------------------------------------------------------
    9-   34 (38.92/14.03)	......HHHSG.......ASDPN.SALTYGTSTLGQAAAA
   39-   78 (58.56/33.31)	GYsvqaHPSAGIGSYANLSANMNASALNNPYSNMPSFTGM
   83-  112 (50.44/21.69)	GH....HTLNGYGSMPSMASTM..SSLTMGPSAMGS....
  545-  573 (39.76/14.52)	..........GNGS.STAAAQLSYNSLSPMMSQIGQSSAM
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     106.98|      26|      28|     439|     464|       4
---------------------------------------------------------------------------
  410-  427 (32.32/13.04)	N..AN....DMA....GP..SADTRHST.PN
  439-  464 (48.10/22.71)	D..VNLLQQAMA.ENNSP.NSAGASCSS.PR
  465-  495 (26.56/ 9.51)	DslVGVGSSSLAnEGLAPvISYGASPNSlPQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      63.93|      18|      54|     522|     540|       5
---------------------------------------------------------------------------
  522-  540 (28.83/19.88)	PFSITnLIDSSKPDSTYNL
  578-  595 (35.09/19.83)	PYYHT.LYSSNNPGSAANL
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP06170 with Med15 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) DCAGNMLLISGDDDQQQQQQQQQQQQQQQQQQQQQQQQKQQQQQQQHVSSALIAGSPSSHGNMLNANDMAGPSADTRHSTPNTLVTTTDGGALDVNLLQQAMAENNSPNSAGASCSSPRDSLVGVGSS
2) RSGIAGSGGKGSRNASMSESGTFQAMVKVEEELEELQHHIQQQRSGQLNEASRGSPCEGTDSMQNHGIDLLTDERKI
346
266
473
342










Molecular Recognition Features






MoRF SequenceStartStop




1) SMPYYHTLYS
576
585