<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP06159

Description Transcription factor SUM-1
SequenceMLLVIFEAIAQQRGCGSILKPCVRAELLCRTVVRVAVAVSAFIYERYKLLLDKQGEHLTVVTSTAPLVRTVGAAEHAVFIRMNTDMAGCQYDPIYGYSSNLTQTSRLTTSTEFANLGPAPGNITAAFPNQTAVTAAADYATITPNPYEATSLYHRYPYYNPYSTGPPTFYPDLASFTSSVQAGSQKAQEYAAVPASLLEAVEPAASKKSSTGSSSSQQYGQQQQAQQQQQQQQQQQQQQQQQQQAQQHLGAGGSTERRIKEEVLDDALHGKESLTMTDAEEHIPHVLAPSTDGHQPRRCLLWACKACKKKTVTIDRRKAATMRERRRLRKVNEAFEILKRRTCANPNQRLPKVEILRNAIEYIDSLEEMMHGAGKLGKTLAGIANPSQMPPANVSPNDTSTGDFIATNGGPFYQASDEKVLTVFSDVEVSAVSMQAQQQPQVPGQSQQSQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQRYGNSSRGSSSGDAIFEQTNTNNGNENTAVVSSLDCLSQIVESIITKKQNHALGENGFGSNQMIELGSPATSDEVGVGGMISPNSNNGRSQADSMSNDDDDAVDGEHSSHNSPQASSDQMQK
Length602
PositionKinase
OrganismTrichinella patagoniensis
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Nematoda> Enoplea> Dorylaimia> Trichinellida> Trichinellidae> Trichinella.
Aromaticity0.05
Grand average of hydropathy-0.730
Instability index60.50
Isoelectric point5.89
Molecular weight65906.02
Publications









Function






Annotated function


GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
DNA binding	GO:0003677	IEA:UniProtKB-KW
protein dimerization activity	GO:0046983	IEA:InterPro

GO - Biological Process
muscle organ development	GO:0007517	IEA:InterPro
regulation of transcription, DNA-templated	GO:0006355	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats
>MDP06159
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     109.89|      12|      19|     217|     228|       1
---------------------------------------------------------------------------
  217-  228 (26.97/ 7.87)	QQYGQQQQAQQQ
  229-  240 (29.59/ 9.22)	QQQQQQQQQQQQ
  441-  452 (23.73/ 6.20)	QVPGQSQQSQQQ
  462-  473 (29.59/ 9.22)	QQQQQQQQQQQQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      57.42|      19|      22|     316|     336|       3
---------------------------------------------------------------------------
  316-  336 (27.34/22.23)	RRKAATmrERRRLRKV...NEAFE
  340-  361 (30.08/17.41)	RRTCAN..PNQRLPKVeilRNAIE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      37.60|      13|      19|     174|     186|       4
---------------------------------------------------------------------------
  174-  186 (22.09/13.29)	ASFTSSVQ.AGSQK
  195-  208 (15.51/ 7.34)	ASLLEAVEpAASKK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      69.22|      20|      23|     108|     127|       6
---------------------------------------------------------------------------
  108-  127 (34.55/19.54)	TTSTEFANLGPAPGNITAAF
  134-  153 (34.67/19.63)	TAAADYATITPNPYEATSLY
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      64.62|      20|      20|     476|     495|       7
---------------------------------------------------------------------------
  476-  495 (34.79/21.05)	QQQQQRYGNSSRG.SSSGDAI
  497-  517 (29.82/16.92)	EQTNTNNGNENTAvVSSLDCL
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      55.69|      20|      24|     519|     541|       8
---------------------------------------------------------------------------
  519-  541 (29.48/23.48)	QIVE..SIITKKQnhaLGENGF...GSN
  542-  566 (26.21/12.96)	QMIElgSPATSDE...VGVGGMispNSN
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP06159 with Med12 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) AAVPASLLEAVEPAASKKSSTGSSSSQQYGQQQQAQQQQQQQQQQQQQQQQQQQAQQHLGAGGSTERRIKEEVLDDALHGKESLTMTDAEEHIPHVLAPSTD
2) AGKLGKTLAGIANPSQMPPANVSPNDTSTGDFIATNGGPF
3) ESIITKKQNHALGENGFGSNQMIELGSPATSDEVGVGGMISPNSNNGRSQADSMSNDDDDAVDGEHSSHNSPQASSDQMQK
4) VSMQAQQQPQVPGQSQQSQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQRYGNSSRGSSSGDAIFEQTNTNNGNENTAVVSS
191
373
522
432
292
412
602
513










Molecular Recognition Features






MoRF SequenceStartStop




1) LYHRYPYY
2) QQQQQQQQQQ
152
471
159
480