<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP06133

Description Mediator of RNA polymerase II transcription subunit 24
SequenceMTLVSICEKKSDLISINIIGIPRLLSQLVAEGVPKETLLGSLRRIAASEAVLNISDTKARCNTLQAFLNVLSELGILQESEKDTLMAIRDEMRKELCVQEGQPTVNLVLRAEFTLQSIVKAFDAHQALERWPQMLNTMMSGKSLLYICAAAISIDQLNLLAERLIKITETYKEVVPVVEDAQKSVPPSHDLFDMSFLLLHRLSQYYSTTTCLRPGDPFFKTWYFSSAIDLVRNMFDPADLPQLLNNVPMDLEQARDVLSRLRVGQPGWLNIKTWYCIIDLIPSIVQLVLNEVLLDTISIEELKHIFSGLLFLNIHGVSCMCSPLLCFAQFVALQKTDEATKLANSLFSFFESITPSDAERNRQTDRQTFMVNSAKKLFSAYRELPVTLMHVLRMNRSPPQLTHSSDDHFPVIGKPENIRSFFAASERAGYLTAALIARIIVLVESDQYDSWLSAFIEALQKVNTMQGMEKWCNLNLACCFIKPKECTLALIPLLSNYVLHDDRDLFCVAPRGNILAFFLVKLYLIALRHTTVTAVDKAETADISMDDCSLQNNTNSTTADRSAVIASLRELFNCKFEVVRSGELCPTVAFVSNFLYCLSEYSTPEAELIKNEIPMHLIFSLLRADPDVLSMRTVLRLFDLKDEIQRRKALQTAFLLRRKQYL
Length662
PositionTail
OrganismTrichinella pseudospiralis (Parasitic roundworm)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Nematoda> Enoplea> Dorylaimia> Trichinellida> Trichinellidae> Trichinella.
Aromaticity0.08
Grand average of hydropathy0.116
Instability index46.10
Isoelectric point5.88
Molecular weight74921.38
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP06133
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     125.83|      37|      42|     270|     311|       1
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  220-  261 (43.96/20.14)	..KTWYfsSAIDLVrnmfdPADLPQLLNNVPMD...LEQARDVLSRL
  270-  309 (59.96/43.93)	NIKTWY..CIIDLI.....PSIVQLVLNEVLLDtisIEELKHIFSGL
  313-  331 (21.90/ 6.98)	NIHGVS..CMCSPL.....LCFAQFV.....................
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      56.49|      17|      28|     334|     350|       2
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  334-  350 (29.99/22.38)	QKTDEATKLANS...LFSFF
  362-  381 (26.50/18.87)	RQTDRQTFMVNSakkLFSAY
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     180.89|      60|     387|      18|      82|       3
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   18-   82 (80.55/71.43)	IIGIPRLLSQLVAEGVPKETLLGSLrrIAASeAVLNISDTKArcNTLQAFLNVLSELGILQESEK
  411-  470 (100.34/67.95)	VIGKPENIRSFFAASERAGYLTAAL..IARI.IVLVESDQYD..SWLSAFIEALQKVNTMQGMEK
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP06133 with Med24 domain of Kingdom Metazoa
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