<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP06127

Description Pyrroline-5-carboxylate reductase
SequenceMSDRLTQLQDCINELASQICNSTGVLQQAAPPSNFENNDQFSTGAEDNAELFAKLVASTSSDIDMLVDLLPNEEPSQDLQKEQFSELNHLNSEAAESLRLSVERGQVLLERIKNIFITMTTQKISPSEDSFFNMNIGFVGAGKMGQAMIRGMISSGKFAAQKITASAPVEDRHYLDEISKVNINVTHSNLDLARTSDVIIFAIPPSISWTVVSEMKNTLNNDKLILSIMNGVAMNTIEQAAGKKLRIARAMPNMAATVRRSATAYALNERCTSEDEALVNGLLSCVGCAVRLPENLINSATGLSGCGPAYMFTVLEAMAEGGVKAGLPRDIAQQLAVNTMLGSAEMVIQTGKHPTILRESIESPGGSTVVGVHELEKAAFRSALINAVEAATNHAFKQDNIQI
Length403
PositionMiddle
OrganismTrichinella pseudospiralis (Parasitic roundworm)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Nematoda> Enoplea> Dorylaimia> Trichinellida> Trichinellidae> Trichinella.
Aromaticity0.04
Grand average of hydropathy-0.067
Instability index46.39
Isoelectric point4.97
Molecular weight43404.90
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
pyrroline-5-carboxylate reductase activity	GO:0004735	IEA:UniProtKB-EC

GO - Biological Process
L-proline biosynthetic process	GO:0055129	IEA:UniProtKB-UniPathway









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP06127
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     108.31|      33|      41|      17|      50|       1
---------------------------------------------------------------------------
   17-   50 (52.71/28.83)	SQICNSTGVLQQAAPPSNFEnNDQFSTGAEDNAE
   61-   93 (55.60/26.86)	SDIDMLVDLLPNEEPSQDLQ.KEQFSELNHLNSE
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     105.03|      31|      44|     235|     265|       2
---------------------------------------------------------------------------
  235-  265 (50.21/29.10)	NTIEQAAGKKLRIARAMPNMAATVRRSATAY
  280-  310 (54.82/32.34)	NGLLSCVGCAVRLPENLINSATGLSGCGPAY
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      37.65|      11|      41|     122|     132|       3
---------------------------------------------------------------------------
  122-  132 (21.04/15.12)	QKIS...PSEDSFF
  161-  174 (16.61/10.53)	QKITasaPVEDRHY
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP06127 with Med21 domain of Kingdom Metazoa
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