<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP06125

Description Transcription factor SUM-1
SequenceMATASPQQRGCGSILKPCVRAELLCRTVVRVAVAVSAFIYERYKLLLDKQGEHLTVVTSTAPLVRTVGAAEHVVFIRMNTDMAGCQYDPIYGYSSNLTQTSRLTTTTEFANLGPAPGNISAAFPNQTAATAAAAEYATITPNPYEATSLYHRYPYYNPYSTGPPTFYPDLASFTSSVHAGSQKAQEYAAVPASLLEAVEPAASKKSSTGSSSSQQYGQQQQSQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQAQQHLGAGGSTERRIKEEVLDDALHGKESLTMTDAEEHIPHVLAPSTDGHQPRRCLLWACKACKKKTVTIDRRKAATMRERRRLRKVNEAFEILKRRTCANPNQRLPKVEILRNAIEYIDSLEEMMHGAGKLGKTLAGIANPSQIPQANVSPNDTSTGDFIFQATNGGPFYQASDEKVLTVFSDVEVSAVSMQAQQQPQVPGQSQQPQQQQQQQQQQQPQQQQQQQQQQRYGNSSRGSSSGDAIFEQTNTNSGNENTAVVSSLDCLSQIVESISTKKQNHALGENGFGSNQMIELGSPATSDEVGVGGMISPNSNNGRSQADSISNDDDDVVDGEHSSHNSPQASSDQMQK
Length603
PositionTail
OrganismTrichinella pseudospiralis (Parasitic roundworm)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Nematoda> Enoplea> Dorylaimia> Trichinellida> Trichinellidae> Trichinella.
Aromaticity0.05
Grand average of hydropathy-0.774
Instability index61.65
Isoelectric point6.04
Molecular weight65953.85
Publications









Function






Annotated function


GO - Cellular Component
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
DNA binding	GO:0003677	IEA:UniProtKB-KW
protein dimerization activity	GO:0046983	IEA:InterPro

GO - Biological Process
muscle organ development	GO:0007517	IEA:InterPro
regulation of transcription, DNA-templated	GO:0006355	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP06125
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     147.66|      18|      18|     218|     235|       1
---------------------------------------------------------------------------
  218-  235 (40.49/12.30)	QQQQSQQQQQQQQQQQQQ
  237-  254 (38.76/11.51)	QQQQQQQQQQQQQQQQAQ
  449-  466 (37.50/10.92)	QPQVPGQSQQPQQQQQQQ
  467-  482 (30.91/ 7.88)	QQQQPQQQQQQQQQQR..
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      53.34|      16|      20|     124|     141|       2
---------------------------------------------------------------------------
   99-  114 (27.44/13.53)	QTSRLTTTTEFANLGP
  126-  141 (25.90/10.80)	QTAATAAAAEYATITP
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      30.45|      10|      20|     334|     347|       3
---------------------------------------------------------------------------
  334-  347 (11.97/18.88)	RRLRKVneafEILK
  356-  365 (18.48/12.28)	QRLPKV....EILR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      35.56|      10|      20|     566|     575|       4
---------------------------------------------------------------------------
  566-  575 (17.54/ 9.36)	SNNGRSQADS
  589-  598 (18.02/ 9.82)	SSHNSPQASS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      41.23|      13|      20|     171|     183|       5
---------------------------------------------------------------------------
  171-  183 (21.54/15.81)	ASFTSSVHAGSQK
  192-  204 (19.68/13.75)	ASLLEAVEPAASK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      51.35|      16|      22|     264|     280|       6
---------------------------------------------------------------------------
  264-  280 (21.91/19.06)	ERRIkEEVLDDALHGKE
  288-  303 (29.45/20.51)	EEHI.PHVLAPSTDGHQ
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP06125 with Med15 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) AAVPASLLEAVEPAASKKSSTGSSSSQQYGQQQQSQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQAQQHLGAGGSTERRIKEEVLDDALHGKESLTMTDAEEHIPHVLAPSTD
2) GKLGKTLAGIANPSQIPQANVSPNDTSTGDFIFQATNG
3) VESISTKKQNHALGENGFGSNQMIELGSPATSDEVGVGGMISPNSNNGRSQADSISNDDDDVVDGEHSSHNSPQASSDQMQK
4) VSMQAQQQPQVPGQSQQPQQQQQQQQQQQPQQQQQQQQQQRYGNSSRGSSSGDAIFEQTNTNSGNENTAVVS
188
382
522
442
300
419
603
513










Molecular Recognition Features






MoRF SequenceStartStop




1) QQQPQQQQQQQQQQRY
2) SLYHRYPYYN
468
148
483
157