<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP06109

Description Mediator of RNA polymerase II transcription subunit 23 (Fragment)
SequenceLNSFVAVAADGTRQSIAENEELMRIIILTLARSTVISKVLGPRKVLIHLKSLADFLVYETNSADVNRCVDVLNRLIFKYAVVPLERFMLTMLLRDYEGNDAFYALLIVMLLVQRSEELRSAVADCVAMLPSDYWHCQDWNDKYQAYQLKHAERTWSQVHTELSRASLTPNDCPLPVYFGTRCLQMLPVVDLLLQKLVESPAACLKFLDSTLSILGPLYRFHPYPVSFLYSTFRFYEKRLVEAPAIKQKLALAVHGACVPSRDDHWLLSAEFVSCVGSGPVTDRGPWVPDLNYYATLVRRLMDTFSEPRQQWSRKSDLRFVEFNNFQTHALYCICIELMSLSVSVVDVGNALITLVTHWHSLVDKNTVMYWVNAIGLIFSALPISYMEPFYQTILTTLCSDHMNSMNTDVSNKLDFEKRSKLMEDCYPARILALCHAVWLHSASGYLQLLPQALRSTWIPHVRSEGQFLYVCHLVAPFLQRFYQERTKFTMDITTDLYQMLYNVDCEVSSWNYEDLICDFFYHVKYMYVGDSVRQETDRIIPMLRTSLQQKLRYISFAQGEQSGTPFSEMINPIKFLGIQMVVWLQRLPIFGETAQHFWLAVTKLGDPVMTFSLYFPALFPFFGTAAVDMVIVGAFSEICNCVLKWILLDDRPYWWVHTAGVSGQLSHPLKQFQWTCETGPGSPSGHAMVSASVWFNLLYNLQSDLVLGDFSGLCWLLYVVFLIAVSISRTYISAHFPDQVILGIVVGICIALVTRSLVGHRRRQWSNLIAFMIVLLLIALSVHEAHRFLGVDTHRSIELAAKYCHRAEWIHQSTTPLASFFRDVGVLISIAVLLANKSMLTNNNNNNSTSKPFSSKFAQALLGVGLNQLVALIPIGRLPAALFYDSHWCKHLLFCC
Length896
PositionTail
OrganismTrichinella pseudospiralis (Parasitic roundworm)
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Nematoda> Enoplea> Dorylaimia> Trichinellida> Trichinellidae> Trichinella.
Aromaticity0.12
Grand average of hydropathy0.232
Instability index40.65
Isoelectric point7.02
Molecular weight102176.73
Publications









Function






Annotated function


GO - Cellular Component
integral component of membrane	GO:0016021	IEA:UniProtKB-KW
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP06109
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     391.80|     124|     284|     138|     421|       1
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  257-  385 (211.64/236.54)	CVPSR.....DDHWLLSAE.FVSCVgsgPVTDRGPWVPDLN......YYATLVRRLMDTFSEPRQQWSR..KSDLRFVEFN......NFQTHALYC...ICIELMSLSVSVVDVGNALITLVThwHSLVDKNTVMYWVNA..IGLIFSAL..PISY
  425-  575 (180.17/130.04)	CYPARilalcHAVWLHSASgYLQLL...PQALRSTWIPHVRsegqflYVCHLVAPFLQRFYQERTKFTMdiTTDLYQMLYNvdcevsSWNYEDLICdffYHVKYMYVGDSVRQETDRIIPMLR..TSLQQKLRYISFAQGeqSGTPFSEMinPIKF
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      90.40|      26|      33|     588|     619|       2
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  588-  613 (47.45/40.85)	PIFGETAQHFWL..AVTKLGDPVMTFSL
  620-  647 (42.95/21.66)	PFFGTAAVDMVIvgAFSEICNCVLKWIL
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      50.30|      14|      34|     704|     717|       3
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  704-  717 (26.54/17.21)	DLVLGDFSGLCWLL
  739-  752 (23.76/14.61)	QVILGIVVGICIAL
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     120.80|      38|      42|     175|     215|       4
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  175-  215 (61.50/41.27)	PVY.FGTRCLQML.PVVDLLLQKLVESPAACLKFldsTLSILG
  216-  255 (59.31/32.88)	PLYrFHPYPVSFLySTFRFYEKRLVEAPAIKQKL...ALAVHG
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP06109 with Med23 domain of Kingdom Metazoa
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