<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP06102

Description Zinc finger MIZ domain-containing protein 1 (Fragment)
SequenceLSTSKSKLHRKQHCSAGRTVSVMIDNKMISKPSMVTATQQYDELLWSRNGSPHGSAYTPSYSGMPPAYANGTTMLNYNSNPLSAATANVAGPVSGYSGDSTVVNGSKAVTQPTPNVNTCYPPQDMGAGPVPGPFNSAAASVYGPGSTAADFGPPSVAAPPVAAAVDHNQYAAATYQHQSAPQIPVYNGQQYPPVGNGPPPSYPIQGRLMQQNAMTRSQMPVSYMNSGSRVQSSNMTVGQSQSTSALRYSLQQTQQCVTNSGRPPTALPVMTPTMQAQQQQQQQQQQQQQQQQQQQQQQQSQSLSAQQSQQQSQLQQYPSNMPSIGQTGATLHHSQQTVVDPTTGAVTPYGTASQPPIVNGPYAKYPPNMPPRNTIYYGNPSSASQAAALPGKAVCNYVNQNFNPQSTMTPGYQHVQAVRQTHQMPIVPPNMVPNQRPIYPTANQYQVPTPIPALYSDVKPVILPSDDADPRMAFPVKDGVILQPFRLEHNIPVSQICFFIAPEQFGLLCSDPDLDIQLKCFHADDRLMYNNWPHNANVQIVVNNTPVVVRHIDRPLYVKTLCQPNKNTLQIAVQQCCCSHLFMLSLTTRPPVERVLSNLVRRKLLSVDNAIDKIKRSFQLAEMGDGQVADIERMSTTISLKCPITMGKITLPARCQDCRHIQCFDLKAFLILNKDRLHWQCPLCGRPAILDNLEIDQYVWGILTNLVKFPEVGEVLIDSNASWKAHASIGREQQQSLGCNPPKRAKTSEANCSTDPSVCSWNMTSVRNYASTSNNNNPVAVTGLQVPIERVPNTSISQIMDMKTTVPPNHTVKKQSQQQQQQQQQQQQQQQLQQQQQQQQQQLQQQQQQQYQYYLSPEQQQQMMHQQQQQQMMHQQQQQQMMQQQQHHHHQQQQQQQQQQQQQQQQALMNSVGSGGGAAAGGGHPTGSIENGNSRLMAEPSTPKQMLKYGPPTPATPSANPPSVGGPRSVGNPPSVEGSSGNGGGSGGNSGYVMQQCSTQANLQLNIDGNPTGSAPYTPASVGSAGSQQGSHCVNVASNEMCNTEFSDLTFDTADLLPGDTASENLGNFFADSTMPDPGEFIQYFESTNFGEFGLSTDRLDVPLFDLEDGKRKSVGILDDISSNPSKLLLDDHKKTANPKKTTHLKEEKKRSMAGDDDDDPLKPTLLSSSEMDDILSLLQS
Length1181
PositionKinase
OrganismTrichinella sp. T6
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Nematoda> Enoplea> Dorylaimia> Trichinellida> Trichinellidae> Trichinella> unclassified Trichinella.
Aromaticity0.06
Grand average of hydropathy-0.677
Instability index59.92
Isoelectric point6.86
Molecular weight129187.87
Publications









Function






Annotated function


GO - Cellular Component
GO - Biological Function
zinc ion binding	GO:0008270	IEA:InterPro

GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP06102
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             5|     161.30|      14|      15|     277|     290|       1
---------------------------------------------------------------------------
  286-  299 (34.97/10.19)	QQQQQQQ.QQQQQQQ
  822-  835 (32.50/ 9.01)	QQQQQQQ.QQQLQQQ
  836-  850 (30.57/ 8.09)	QQQQQQQlQQQQQQQ
  869-  882 (28.30/ 7.00)	QQQMMHQ.QQQQQMM
  893-  906 (34.97/10.19)	QQQQQQQ.QQQQQQQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      51.67|      17|      20|     360|     379|       2
---------------------------------------------------------------------------
  364-  383 (28.21/15.09)	KYPPNMP....PRNTiyyGNPSSA
  956-  976 (23.46/ 6.03)	TPSANPPsvggPRSV...GNPPSV
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     252.59|      59|      64|      52|     115|       3
---------------------------------------------------------------------------
   52-  110 (90.72/36.44)	...............PH.....GSAYTPSYSGMPPAYANGTTMLNYNsnPLSAATANVAGPVSGYSGDSTVVNGSKAVT
  111-  174 (76.00/30.04)	QPtpnvntcyppqdmGA.....GPVPGPFNSAAASVYGPGSTAADFG..PPSVAAPPVAAAV.....DH...NQYAAAT
  178-  238 (85.87/31.11)	QS............aPQipvynGQQYPPVGNGPPPSYPIQGRLMQ......QNAMTRSQMPVSYMNSGSRVQSSNMTVG
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     104.98|      24|      64|     403|     426|       5
---------------------------------------------------------------------------
  403-  426 (43.04/17.59)	NPQSTMTP........GYQHVQAVRQTHQMPI
  427-  449 (35.59/13.26)	VP.PNMVP........NQRPIYPTANQYQVPT
  463-  493 (26.35/ 7.88)	LPSDDADPrmafpvkdGVI.LQPFRLEHNIPV
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      90.31|      33|      65|     911|     955|       6
---------------------------------------------------------------------------
  911-  955 (53.87/46.32)	SVGS................GGGAaagGghptgsienGNSR.LMAEPSTPKQM.LK.YGPPT......PA
  963- 1020 (36.45/14.33)	SVGGprsvgnppsvegssgnGGGS...G.........GNSGyVMQQCSTQANLqLNiDGNPTgsapytPA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      60.36|      19|      20|     322|     341|       8
---------------------------------------------------------------------------
  321-  340 (28.04/17.28)	MPSiGQTGATLHHSQQTVVD
  341-  359 (32.32/15.93)	PTT.GAVTPYGTASQPPIVN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      87.08|      21|      22|    1037|    1057|      11
---------------------------------------------------------------------------
 1037- 1057 (36.88/23.68)	ASNEMCN.TEFSDLTF.DTADLL
 1062- 1082 (29.54/17.56)	ASENLGN.F.FADSTMpDPGEFI
 1083- 1101 (20.66/10.14)	QYFESTNfGEFG.LST.DRLD..
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      30.61|       9|      36|     641|     653|      14
---------------------------------------------------------------------------
  641-  653 ( 9.65/15.49)	KCPITmGKitlPA
  680-  688 (20.96/10.78)	QCPLC.GR...PA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      43.45|      10|      22|     858|     867|      15
---------------------------------------------------------------------------
  858-  867 (21.10/ 8.42)	EQQQQMMHQQ
  883-  892 (22.35/ 9.40)	QQQQHHHHQQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      72.45|      21|      36|    1108|    1128|      16
---------------------------------------------------------------------------
 1108- 1128 (35.47/23.88)	EDGKRKSVGILDDISSNPSKL
 1147- 1167 (36.98/25.23)	EEKKRSMAGDDDDDPLKPTLL
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP06102 with Med12 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) LLLDDHKKTANPKKTTHLKEEKKRSMAGDDDDDPLKPTLL
2) PQIPVYNGQQYPPVGNGPPPSYPIQGRLMQQNAMTRSQMPVSYMNSGSRVQSSNMTVGQSQSTSA
3) RVPNTSISQIMDMKTTVPPNHTVKKQSQQQQQQQQQQQQQQQLQQQQQQQ
4) VSGYSGDSTVVNGSKAVTQPTPNVNTCYPPQDMGAGPVPGPFNSAAA
5) YLSPEQQQQMMHQQQQQQMMHQQQQQQMMQQQQHHHHQQQQQQQQQQQQQQQQALMNSVGSGGGAAAGGGHPTGSIENGNSRLMAEPSTPKQMLKYGPPTPATPSANPPSVGGPRSVGNPPSVEGSSGNGGGSGGNSGYVMQQCSTQANLQLNIDGNPTGSAPYTPASVGSAGSQQGSHCV
6) YSLQQTQQCVTNSGRPPTALPVMTPTMQAQQQQQQQQQQQQQQQQQQQQQQQSQSLSAQQSQQQSQLQQYPSNMPSIGQTGATLHHSQQTVVDPTTGAVTPYGTASQPPIVNGPYAKYPPNMPPRNTIYYGNPSSA
1128
181
790
93
854
248
1167
245
839
139
1034
383










Molecular Recognition Features






MoRF SequenceStartStop




1) EFIQYFE
2) LLLDDHKKTANPKKTTHLKEEKKRSMAGDDDDDPLKPTLLSSSEMDDILSLLQS
3) QQYQYYLS
1080
1128
849
1086
1181
856