<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP06098

Description RNA polymerase II-associated protein 3
SequenceMAKLMKENFPPDRERVVTKTSELQITLIPTHNKKSASLILCLSTELDCLRIFQLTVVMQSDKNSNEAPQRIEELIGELQQLRKDIRLCFRGVDCSPEEQVHRVRVLYKELLLKDRLVKHLKQISVQLVNVQVNDSQLLNEEVFKIPDLLDVGPSTEKASSSNNNNGKKLSLSCPKCSCIILRENHGEQVTVEKELPELSLKADGTVDMKTFTEFVRVDDIYDFENIGFSRDSNGVQYLLCAACEIGPLGFHDLTTKLSYVASVRHNVNLVMLVRKERKDISEKDAQKALFEKESGNSFYVKKDYEKAIMCYSRSISADPFRPVVYCNRAMAYLKLKNYAEAYADCSKALTFDSTYVKALYRRGMASKGLNNFDDAVEDFQHVLTLDPNNDIAKKELEEIISKVKPAENDPLLVYPVENPDEKEYQKPLKVIIVRDAVKKSQFNSQQPALSDESNVTKQSEQKISDYKLNASIKITRIPKCYAELRADWISIKEEPLALADYILNIPCDCFSNLLGEFLDGEFVANLLKAFMIKVNSEPQCSISCMERLELIGKAKRFDIVVLFLSQQENMVLNVKNTWHLKTVLDKAKHVCSKDQVQRWDDLFKKYIETAINKNDNEEEASVESFPKFYPTRIYPLSRVSVNECSSALVLK
Length651
PositionMiddle
OrganismTrichinella sp. T6
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Nematoda> Enoplea> Dorylaimia> Trichinellida> Trichinellidae> Trichinella> unclassified Trichinella.
Aromaticity0.08
Grand average of hydropathy-0.362
Instability index39.62
Isoelectric point6.25
Molecular weight74362.65
Publications









Function






Annotated function


GO - Cellular Component
GO - Biological Function
guanyl-nucleotide exchange factor activity	GO:0005085	IEA:UniProtKB-KW

GO - Biological Process
protein transport	GO:0015031	IEA:UniProtKB-KW
small GTPase mediated signal transduction	GO:0007264	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP06098
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      99.18|      31|      32|     299|     330|       1
---------------------------------------------------------------------------
  299-  330 (52.73/36.33)	YVK.KDYEKAIMCYSRSISADP.FRPVVYcNRAM
  332-  364 (46.46/26.52)	YLKlKNYAEAYADCSKALTFDStYVKALY.RRGM
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      89.88|      28|      29|      23|      50|       2
---------------------------------------------------------------------------
   23-   50 (47.66/37.95)	LQITLIPTHNKKS...ASLILCLSTELDCLR
   52-   82 (42.22/32.69)	FQLTVVMQSDKNSneaPQRIEELIGELQQLR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     217.92|      74|     302|     121|     203|       3
---------------------------------------------------------------------------
  121-  203 (97.96/87.10)	KQISVQLVNVQVNDSQLlNEEVFKIPDLLDVGPSTE.KASSSNNNNGKKLSlSCPKCsciiLRENHGEQVTVeKELPeLSLkAD
  426-  500 (119.95/72.79)	KPLKVIIVRDAVKKSQF.NSQQPALSDESNVTKQSEqKISDYKLNASIKIT.RIPKC....YAELRADWISI.KEEP.LAL.AD
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP06098 with Med9 domain of Kingdom Metazoa
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