<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP06095

Description Ectonucleoside triphosphate diphosphohydrolase 1
SequenceMDEGRKNINARKAMLLKEYQVLLQRSVKSIRENFTEIIRMAKVGEEGQVSRLTEYEHELFEMQIRAANMTHAAEALIKMVTDLKQFLILNDFAYINESITTTAVHSQIAQREFRDKLIAVKEEMTFYLQEAEQEYYNTAINMTLDEFGTELYVDPWQTFVSIKGKLRKRAFRSPNLAEVVKDYDALASRLLDENCTEYSALCRMNMAKCKNQLGNTDQEAVEYRTAGRLYIRAEKEKESVENRLSMECLYMAMHCYNEAIRLHLSQGQKLLAASLLIELGKELACMQHPEDAIQNFEKAIHLLDTHPHAVGHALRWKLCVETSVGFLADARRTSNFYRQIVESWPNSGFRKLHLNELEIITVMLLLALKPIKSEMNDFEKRVLQRYSDETDEALLSSYEGSLLPNDSYIISVEIYLHLKSFVLAINNNDPSAADIALTAIHHRNVKLVHSAGADASLPLRVFIKSLFYNESSVSLEVDSDFKVRDVINAYAYRTGHSEKDEEFVLRFHDHSSLNSEDVLHVLGIYNDEELIISVRGEDSRRSRNSWWWLGSVALLISLVGLTAVSVLFALSGDLPDEFGIIIDAGSSHSGLYIYTWNGRKNKTGVIKQYAPSCSTEDGISSFTDNPTDAGNSLIFCLNNASATVPSKRHSSTAMYLAATAGMRILEIRDPLSSCKITNAVSNTMHSYNFLFKNASIISGIDEGIYGWITLNFLSHRLMNSASKLNDIRPLTIGAMDLGGASTQIIFEINSSEFTERNYSLKLFGETYNLFVDSYLCCGANEVQRIIQAQIVAEDTTNQQPLHPCLPLNYTMNVTSEQIFLMPCSLNQKPNNVLPNYVFRGSSDPHSCLKKIRYMLDTSACSVKKAKIPKPRGEFMAFSGMYWTAKFFNCTSGCSYNKFFENVQNYCEKSWSSIEAAAYPYKKTFLSTYCFTGLYSLTLFKDAYHFSDAQIQKIEFVNEIDSTEIGWTLGFMLNATNQLPEEQPIEHIGLIEFSLITTICCIVRKMVSTFLPWSQCSK
Length1017
PositionHead
OrganismTrichinella sp. T6
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Nematoda> Enoplea> Dorylaimia> Trichinellida> Trichinellidae> Trichinella> unclassified Trichinella.
Aromaticity0.10
Grand average of hydropathy-0.186
Instability index35.86
Isoelectric point5.81
Molecular weight115402.34
Publications









Function






Annotated function


GO - Cellular Component
integral component of membrane	GO:0016021	IEA:UniProtKB-KW
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
ATP binding	GO:0005524	IEA:UniProtKB-KW
hydrolase activity	GO:0016787	IEA:UniProtKB-KW
transcription coregulator activity	GO:0003712	IEA:InterPro

GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP06095
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      67.03|      19|      22|     217|     238|       1
---------------------------------------------------------------------------
  192-  210 (35.78/19.39)	DENCTEYSALCRMNMAKCK
  217-  235 (31.25/24.20)	DQEAVEYRTAGRLYIRAEK
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      41.46|      10|      22|     795|     804|       2
---------------------------------------------------------------------------
  795-  804 (22.08/15.36)	TTNQQPLHPC
  814-  823 (19.38/12.57)	TSEQIFLMPC
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      58.60|      20|      22|     463|     484|       3
---------------------------------------------------------------------------
  463-  484 (23.91/20.03)	IKSLFYNESSvSlEVDSDFKVR
  487-  506 (34.69/19.53)	INAYAYRTGH.S.EKDEEFVLR
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      61.71|      18|     174|     753|     772|       4
---------------------------------------------------------------------------
  753-  772 (26.34/27.41)	FTErNYSLKLFGETYNlFVD
  930-  947 (35.37/24.51)	FTG.LYSLTLFKDAYH.FSD
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     103.52|      32|     199|      72|     136|       7
---------------------------------------------------------------------------
   88-  119 (52.42/78.79)	ILNDFA...YINESITTTAVHSQIAQREFRDKLIA
  143-  177 (51.10/15.71)	TLDEFGtelYVDPWQTFVSIKGKLRKRAFRSPNLA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      64.74|      19|      25|     579|     597|      10
---------------------------------------------------------------------------
  579-  597 (35.62/24.88)	GII...IDAGSSHSGLYIYTWN
  604-  625 (29.13/18.89)	GVIkqyAPSCSTEDGISSFTDN
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      42.95|      11|     138|     851|     862|      12
---------------------------------------------------------------------------
  851-  861 (20.71/12.69)	IRYMLDTSACS
  884-  894 (22.23/ 8.82)	AKFFNCTSGCS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      39.35|      11|      24|      31|      41|      13
---------------------------------------------------------------------------
   31-   41 (19.58/11.57)	RENFTEIIRMA
   57-   67 (19.76/11.73)	HELFEMQIRAA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      64.80|      21|     253|     709|     733|      18
---------------------------------------------------------------------------
  709-  733 (31.10/31.00)	TLNFlshrLMNSASKLNDIRPLT.IG
  967-  988 (33.69/21.79)	TLGF....MLNATNQLPEEQPIEhIG
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP06095 with Med22 domain of Kingdom Metazoa
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