<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP06094

Description Mediator of RNA polymerase II transcription subunit 26 (Fragment)
SequenceLFKQMQALPVERLKVRLLSCLDREKKVNNVAKACEAMDAIESVVMTKESLESSRLGLLINEVRRSNQLLHPDLAKRCRLLIKKWRKLISTTPTPTPTPTTTTQPAITDNGVDTAGVAPVAADDRAIRIRIKLGSSVNEATILGGQEKKQQQQQQLDNCGIEQAENRRKRKHISQNAPNNSKMNGISKTHLSAIGGNGGGSGETFSLASTVSKPCKPPRSSSSCSRPVPLPTAPASQPRHPPPPQPPLPPPSAPTPPPPPPPPPPPQSSPPPLPPSPPPPTPPPPPPPSTSPSLTTTSSRPPKLKTTAQLVADLTKCYPEELLVNINTSIGVDSTNALQQATASNSGDDAPSPALLFSAVEHQQPNGGGGGEGNKLELLEKYLAEDADQQQQNQDHVVAGSSSGVCTSSSSVDSDTSSRSSTPSRDKIVRASDDDDDDAPPRSGPDTVSSPSDGGGKPGLVDDGRRPIRRLPPVDRSMLDRLDEIPSPSKSRVSSLKYLDDYSNEPPERTRALAPFEQSLRMLPSEMRQLHSRVLVKTTDGRQVLALPYVDIGLPDFLEYDNSPATTEQLISWEAIRW
Length577
PositionUnknown
OrganismTrichinella sp. T6
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Nematoda> Enoplea> Dorylaimia> Trichinellida> Trichinellidae> Trichinella> unclassified Trichinella.
Aromaticity0.02
Grand average of hydropathy-0.695
Instability index72.41
Isoelectric point8.08
Molecular weight61898.86
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process
regulation of transcription by RNA polymerase II	GO:0006357	IEA:InterPro









Interaction





Binary Interactions











Repeat regions





Repeats

>MDP06094
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     105.74|      18|      19|     248|     265|       1
---------------------------------------------------------------------------
  241-  259 (39.82/10.57)	PPPQPP..lPPPSAPTPPPP.P
  260-  281 (34.98/ 8.33)	PPPPPPqssPPPLPPSPPPPtP
  282-  300 (30.95/ 6.46)	PPPPPP..sTSPSLTTTSSR.P
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|      99.77|      24|     186|     136|     159|       3
---------------------------------------------------------------------------
  136-  159 (41.68/27.26)	VNEATILGGQEKK...............QQQQQQLDNCG
  323-  346 (36.09/22.65)	VNINTSIGVDSTN...............ALQQATASNSG
  359-  394 (22.00/11.01)	VEHQQPNGGGGGEgnklellekylaedaDQQQQNQD...
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      43.23|      13|      19|     471|     483|       4
---------------------------------------------------------------------------
  471-  483 (24.48/13.07)	PPVDR.SMLDRLDE
  487-  500 (18.75/ 8.38)	PSKSRvSSLKYLDD
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      69.22|      19|     222|     216|     237|       5
---------------------------------------------------------------------------
  216-  237 (31.92/16.25)	PPRSSSSCsrpVPLPTAPASQP
  439-  457 (37.30/12.99)	PPRSGPDT...VSSPSDGGGKP
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP06094 with Med26 domain of Kingdom Metazoa


     
       
      
        
        
        


      
      
   
   

      

      














Intrinsically Disordered Regions








IDR SequenceStartStop




1) NEATILGGQEKKQQQQQQLDNCGIEQAENRRKRKHISQNAPNNSKMNGISKTHLSAIGGNGGGSGETFSLASTVSKPCKPPRSSSSCSRPVPLPTAPASQPRHPPPPQPPLPPPSAPTPPPPPPPPPPPQSSPPPLPPSPPPPTPPPPPPPSTSPSLTTTSSRPPKLKTTAQLVADLTKCYPEELLVNINTSIGVDSTNALQQATASNSGDDAPSPALLFSAVEHQQPNGGGGGEGNKLELLEKYLAEDADQQQQNQDHVVAGSSSGVCTSSSSVDSDTSSRSSTPSRDKIVRASDDDDDDAPPRSGPDTVSSPSDGGGKPGLVDDGRRPIRRLPPVDRSMLDRLDEIPS
2) SKSRVSSLKYLDDYSNEPPERTRALAPFEQSLRM
137
488
486
521










Molecular Recognition Features






MoRF SequenceStartStop




1) LLFSAV
2) NKLELLEKYLAEDAD
3) RLLIKKWRKLIS
4) RVSSLKYLDDYS
354
373
78
491
359
387
89
502