<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP06072

Description Mediator of RNA polymerase II transcription subunit 24 (Fragment)
SequenceMAESSMNAVEQLLFDAWSECWPDIIFMKQLRQRIEITNQNIEQLSSLLLYYVTLSEMPNRLMLKYIRFCLDTQVVPCVAFLNVVNSYRCYEKVGCINEILVLVIYCLDKLNCDFCDADVCVRTSILVMNTVLWILAYVEYLLTSNNFPPSAHLWSLVFTLKENKFVQFCNYFVCWELSEFHDQIKVSIVNIKVKIEENRHSFPADLLDNMLTFLSFFDIEKNSYDDLFSANPNEILAKSVRASDSRIPSVVISLSGIFAHVQSMKGIAAMVEALKVAKDIQGESWLNILYDLIMGGILQQHDDSTTLPFSVSSSYLYLRIPRLLSQLVAEGIPKETLIGSLRRIATSEAVLNVSDTKARCNTLQAFLNVLSELGILEESEKDTLMAIRDEMRKELYVQEGQPTINLVLRAEFTLQSIVKAFDAHQALERWPQMLNTMMSGKSLLYICAAAISIDQLNLLAERLIKITETYKEVVPVGEDAQKSLPPSHDLFDMSFLLLHRLSQYYSTTTCLRPGDPFFKTWYFSSAIDLVRNMFDPEDLPQLLKNVPLDLELATDVLSRLRVGQPGWLNIRTWYCIIDLIPSIVQVVLNEVLLDTISIEELKHIFSGLLFLNIHGVSCMCSPLLCFAQYVALQKTDEATKLASSLFSFFESITPSDAERNRQTDRQTFMVNSAKKLFSTYRELPVTLMHVLRMNRAPAQLNHSPDDHFPAIGKPENIRSFFAASERAGYLTAALIARIIVLVESEQYDSWLSAFIEALQKVNTMQGMEKWCNLNLACCFIRPKECTLALIPLLSNYVLHDDRDLFCVAPRGNILAFFLVKLYLIALRYTTPTAVEKAETTEFSVDECSVQNNTNSSTADRSAVITSLRELFSCKFEVVRSGELCPTVAFVSNFLYCLSEYSTPEAELIKNEIPMHLIFSLLRADPDILSMRTVLRLFDLKVDMVLFANIAITVAVKVETEFTHYSRLRYAVWLLLFQFKISVTVTSRSRKKPCWPQS
Length997
PositionTail
OrganismTrichinella sp. T6
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Nematoda> Enoplea> Dorylaimia> Trichinellida> Trichinellidae> Trichinella> unclassified Trichinella.
Aromaticity0.10
Grand average of hydropathy0.167
Instability index46.51
Isoelectric point5.40
Molecular weight113665.78
Publications









Function






Annotated function


GO - Cellular Component
mediator complex	GO:0016592	IEA:InterPro

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP06072
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      34.29|       9|      49|     520|     530|       1
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  520-  530 (13.91/12.33)	TWYfsSAIDLV
  572-  580 (20.38/10.40)	TWY..CIIDLI
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     225.66|      78|     151|     207|     288|       2
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  207-  288 (112.28/94.52)	LDNMLTFLSFFDIEKNSYDDLFSANPNEiLAKSVRASDSRiPSVVISLSGIFAhVQSM.KGIAAMvEAL....KVAKDI.QGESWLNI
  363-  446 (113.38/76.99)	LQAFLNVLSELGILEESEKDTLMAIRDE.MRKELYVQEGQ.PTINLVLRAEFT.LQSIvKAFDAH.QALerwpQMLNTMmSGKSLLYI
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      54.86|      16|     331|     298|     313|       4
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  298-  313 (28.77/19.81)	LQQHDDSTTLPFSVSS
  632-  647 (26.09/17.27)	LQKTDEATKLASSLFS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     140.10|      47|     318|     455|     509|       5
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  455-  509 (71.94/71.40)	QLNlLAERLIKITETYKEVVP.....VgedaqksLPPSHDLF.......DMSFLL..LHRLSQYYSTTT
  772-  832 (68.16/47.65)	NLN.LACCFIRPKECTLALIPllsnyV.......LHDDRDLFcvaprgnILAFFLvkLYLIALRYTTPT
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      78.52|      25|      52|     100|     124|       7
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  100-  124 (46.82/20.69)	LVLVIYCLDKLNCD......................FCDADVCVRTS
  132-  178 (31.70/12.23)	LWILAYVEYLLTSNnfppsahlwslvftlkenkfvqFCNYFVCWELS
---------------------------------------------------------------------------
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No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      91.42|      29|      64|     858|     888|      10
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  858-  888 (46.76/37.70)	ADRSavITSLR...ELFSCKFEVVRSGELCPTVA
  923-  954 (44.67/29.48)	ADPD..ILSMRtvlRLFDLKVDMVLFANIAITVA
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Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP06072 with Med24 domain of Kingdom Metazoa
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