<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Detailed information on MDP06054

Description Mediator of RNA polymerase II transcription subunit 23
SequenceMSVSLSDFEAKVKNLFKEHAKSGIAHFFFRPYLITSSEEYEKEIVISTANELMEIFTSLPQNLQESAFSIVISHRVLSNSANRIVDFFVRNVTQRQMLSIKCICEKLLTCAELNINSCGWNDTFAFFMENISLLDYKGVRDTLKRLLDIPIPVHLQVDQRKSVEAVEKLIKTICDRKNNLLPAYFVITEIIKNLPEQRCFSHWRMADCFTEIIESFRPLAQLNSVCGRTFMTPIPGHVGFYFNAFWKLEALSLRFPLKGLLPYSQDLLNPQMRLLTHVFMHYTYRDAIAVLLGTAKPEKSRIPYFEEVITEIILELMFTAECDHSQLNPQAWRIISTQIIYLTLQQSICFTRLVKILHTKLTHYPYRYARNQLMWCLFNFLSGGMQKYSVEEFAVILDLYRLLYTGRDIFTVSGSDSSCVLMLAPTCIWIHILKKSPSMEVELPPTVNTQRKFLQEALKNKTQFNTDNYMVAVLCNAYSSTSEIFQQDLLPILLENLDNTRGHNSTQASGNFASNATSSMPYPNGAVSEVKLRPLKLEFLDSVSVHVRMNIANSLIGTFGRFMQGKSAWPSPALVETYCRMLTYPDLEILGLKQFTSHIVLTAARHQCCEMMYICCEILNYRLFNIPSTYRVHAIVTLQQTLAFAKFQTNASLYWMLERTLLLQFQWYPHYEIFQAPFARLLNSFVAVAADGTKQSIAENEELMRIIILTLARSTVISSNCDSCFIEGVYRELLNKLPSYSWPQSTLSVFPQVFCSHYTQQQQQQQQQQQQQQQQQQQQPQQPQQQQQPQPQQSNVVVGSSQQPQQQQQSRFLLKQQVDEEYIKHRTFGSELSLIDYFTNTSTSTVYLCLLWRLVYDTGELPAVSMKILEVLGPRKVLVHLKSLADFLVYETNSADVNRCVDVLNRLIFKYAVVPLERFMLTMLLRDYEGNDAFYALLIVMLLVQRSEELRSAVADCVAMLPSDYWHCQDWNDKYQAYQIKHAERNWSQVYVELSRASLTPNDCPLPVYFGTRCLQMLPVVDLLLQKLVESPAACLKFLDSTLSILGPLYRFHPYPVSFLYSTFRFYEKRLVESPAIKQKLALAVHGACVPSRDDHWLLSAEFVGWVGQATDRGPWVPDLNYYGALVRRLIDTFSEPRQQWSRKTDLRFVEFNNFQTHALYSICIELMSLPVGVVDVGNALVTLVTHWHSLVDKNTVMYWVNAIGLIFSALPISYMEPFYQTILTTLCSDHMNSINTDVSNKLDFEKRSKLMEDCYAARILALCHAVWLHSTSGYLQLLPQALRSTWIPHVRSEEQFLYVCHLVAPFLQRFYQERTKFTMDITTDLYQMLYNVDCEVGNWKYEDLICDFFYHVKYMYVGDSVRQDTDRIIPMLRPSLQQKLRYISFAQVGKGSFEEDFTSEMINPIKLLGIQMVVWLQRLPIFGETAQHFWLAVTKLGDPVMTFSLYFPALFPFFGTAALDMVIVGAFSEISNCILKWILLDDRPYWWVHTAGVSGQLSHPLKQFQWTCETGPGSPSGHAMVSASVWFNLLYNLQSDLVLGDLCGICWLLYVVFLIAVSVSRTYISAHFPDQVILGIVVGICIALVTRSLVGHRRRRWSNLIAFMIALLLIALSVHEVHRFFGVDTHRSIELAAKYCHRAEWIHQSTTPLASFFRDVGVLISVAILLANKSMFTNNNKIASKFFSTKFAQALLGVGLNQLVAFIPIGRLPTALFYGMLFVEHFFCFFTTAVLLPVLFTNNSNKLQ
Length1745
PositionTail
OrganismTrichinella sp. T6
KingdomMetazoa
LineageEukaryota> Metazoa> Ecdysozoa> Nematoda> Enoplea> Dorylaimia> Trichinellida> Trichinellidae> Trichinella> unclassified Trichinella.
Aromaticity0.12
Grand average of hydropathy0.075
Instability index45.77
Isoelectric point7.36
Molecular weight200758.46
Publications









Function






Annotated function


GO - Cellular Component
integral component of membrane	GO:0016021	IEA:UniProtKB-KW
nucleus	GO:0005634	IEA:UniProtKB-SubCell

GO - Biological Function
GO - Biological Process








Interaction





Binary Interactions











Repeat regions





Repeats

>MDP06054
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     104.16|      18|      18|     760|     777|       1
---------------------------------------------------------------------------
  760-  777 (36.82/19.71)	QQQQQQQQQQQQQQQQQQ
  778-  795 (36.43/19.43)	QQPQQPQQQQQPQPQQSN
  800-  817 (30.92/15.53)	SSQQPQQQQQSRFLLKQQ
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     155.41|      47|      80|     914|     963|       2
---------------------------------------------------------------------------
  914-  963 (77.00/58.46)	VPLERFMLT...MLLRDYEGNDAFYALLIVMLLVQRseeLRSAVADCVAMLPS
  992- 1041 (78.41/51.84)	VELSRASLTpndCPLPVYFGTRCLQMLPVVDLLLQK...LVESPAACLKFLDS
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             4|     186.89|      37|      80|    1428|    1464|       3
---------------------------------------------------------------------------
 1428- 1464 (64.77/31.26)	QHFWLAVTKLGDP....VMTFSLYFPALFPFFGTAALDMVI
 1467- 1495 (31.19/11.62)	.....AFSEISNC....ILKWILLDDRPYWWVHTAGVS...
 1504- 1540 (46.56/20.61)	QFQWTCETGPGSPsghaMVSASVWFNLLYNL....QSDLVL
 1545- 1574 (44.37/19.33)	GICWLLYVVFLIA....VSVSRTYISAHFP.......DQVI
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      57.72|      15|      85|     273|     287|       4
---------------------------------------------------------------------------
  273-  287 (28.85/18.34)	RLLTHVFMHYTYRDA
  355-  369 (28.86/18.35)	KILHTKLTHYPYRYA
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             3|     163.50|      43|      85|     112|     154|       5
---------------------------------------------------------------------------
   89-  127 (61.58/39.21)	VRNVTQRQMLSIKCICEKLLTC..........................................aELNINSC..GW..NDTF.AFF
  128-  212 (46.10/27.22)	MENISLLDYKGVRDTLKRLLDIPIPVHlqvdqrksveaveklikticdrknnllpayfviteiikNLPEQRCfsHWrmADCF.TEI
  213-  246 (55.82/34.75)	IE..SFRPLAQLNSVCGRTFMTPIPGH.........................................V.....GF....YFnAFW
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      60.87|      16|      29|     579|     595|       6
---------------------------------------------------------------------------
  579-  595 (26.75/25.89)	CRMLtYPDLEILGLKQF
  609-  624 (34.12/27.26)	CEMM.YICCEILNYRLF
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      55.05|      18|      29|     297|     319|       7
---------------------------------------------------------------------------
  297-  319 (26.53/31.53)	PEKSRIpyfeeVITEIIL.....ELMFT
  329-  351 (28.52/17.35)	PQAWRI.....ISTQIIYltlqqSICFT
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     156.52|      49|      84|    1576|    1624|       8
---------------------------------------------------------------------------
 1576- 1624 (80.14/58.07)	GIVVGICIALVTRSLVGHRRRRWSNLIAFMIALLLIALSVHEVHRFFGV
 1658- 1706 (76.38/54.95)	GVLISVAILLANKSMFTNNNKIASKFFSTKFAQALLGVGLNQLVAFIPI
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|     223.37|      73|      84|    1156|    1238|       9
---------------------------------------------------------------------------
 1156- 1238 (114.11/89.93)	QTHALYSICIELMslpvgvVDVGNALVTLVTH..W.HS......LVDKNTVMYWVNAIGlifSALPISYM....EPFYQTILTTLCSDHMNsINTD
 1240- 1325 (109.25/64.28)	SNKLDFEKRSKLM......EDCYAARILALCHavWlHStsgylqLLPQALRSTWIPHVR...SEEQFLYVchlvAPFLQRFYQERTKFTMD.ITTD
---------------------------------------------------------------------------
---------------------------------------------------------------------------
No. of Repeats|Total Score|Length  |Diagonal| BW-From|   BW-To|   Level
             2|      66.18|      21|      38|     456|     480|      12
---------------------------------------------------------------------------
  456-  480 (33.94/29.99)	EALKNKTQFN....TDNYMvavlCNAYSS
  495-  519 (32.24/19.12)	ENLDNTRGHNstqaSGNFA....SNATSS
---------------------------------------------------------------------------




































Explaination for Stockholm format
  The  "Stockholm" format is a system for marking up features in a multiple alignment. These mark-up annotations are preceded by a 'magic' label, of which there are four types. The Stockholm format is used by HMMER, Pfam, and Belvu. Mark-up lines include any characters except whitespace. Underscore ("_") is used instead of space. 

 #=GR (seqname) PP (Generic per-Sequence AND per-Column markup, exactly 1 char per column) where PP is Posterior Probability  [0-9*], (0=0.00-0.05; 1=0.05-0.15; *=0.95-1.00) 
 
 #=GC PP_cons line is Stockholm-format consensus posterior probability annotation for the entire column.  It’s calculated simply as the arithmetic mean of the per-residue posterior probabilities in that column.  This should prove useful in phylogenetic inference applications, for example, where it’s common to mask away non confidently aligned columns of a multiple alignment. The PP_cons line provides an objective measure of the confidence assigned to each column.
 
 #=GC RF line is Stockholm-format reference coordinate annotation, with an x marking each column that the profile considered to be consensus.





Alignment of MDP06054 with Med23 domain of Kingdom Metazoa
Unable to open file!